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Machine Learning Computational Chemistry Jobs in Delaware

R&D Hardware Engineer

Wilmington, DE · On-site

$116K - $182K/yr

Most projects require mechanical, electrical and firmware engineers, as well as chemists and ... Material processing techniques such as precision machining, sheet metal, casting/molding, ceramics ...

R&D Hardware Engineer

Wilmington, DE · On-site

$116K - $182K/yr

Most projects require mechanical, electrical and firmware engineers, as well as chemists and ... Material processing techniques such as precision machining, sheet metal, casting/molding, ceramics ...

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Machine Learning Computational Chemistry information

What is machine learning computational chemistry?

Machine learning computational chemistry is a field that combines machine learning techniques with computational chemistry to accelerate the discovery and design of molecules and materials. By training algorithms on large datasets of chemical information, researchers can predict molecular properties, simulate chemical reactions, and optimize compounds more efficiently than traditional methods. This approach helps reduce the time and cost required for research in drug discovery, materials science, and related fields.

What are some common challenges faced by professionals working in machine learning computational chemistry roles?

One common challenge in Machine Learning Computational Chemistry roles is integrating large and often complex chemical datasets with appropriate machine learning models, which requires a solid understanding of both domains. Professionals may also encounter difficulties in ensuring that their models are both interpretable and generalizable to new data, as overfitting is a frequent issue. Additionally, collaboration with chemists and data scientists is essential, so clear communication across disciplines is key to success. Staying up to date with the latest developments in both computational chemistry and machine learning is crucial for ongoing professional growth.

What are the key skills and qualifications needed to thrive as a machine learning computational chemist, and why are they important?

To thrive as a Machine Learning Computational Chemist, you need a solid background in chemistry, mathematics, and computer science, typically supported by an advanced degree in computational chemistry, cheminformatics, or a related field. Proficiency with programming languages (such as Python), machine learning frameworks (like TensorFlow or PyTorch), and molecular modeling software is essential. Strong analytical thinking, problem-solving skills, and effective collaboration are key soft skills that help drive innovation and teamwork. These skills and qualifications are critical for developing accurate models, advancing research, and translating computational insights into real-world chemical solutions.

What is the difference between Machine Learning Computational Chemistry vs Computational Chemist?

AspectMachine Learning Computational ChemistryComputational Chemist
Required CredentialsAdvanced degrees in chemistry, computer science, or related fields; knowledge of machine learning and programmingDegree in chemistry, chemical engineering, or related fields; strong background in chemical theory and modeling
Work EnvironmentResearch labs, tech companies, academia; focus on algorithm development and data analysisLaboratories, research institutions, industry; focus on chemical modeling and simulation
Employer & Industry UsageTech firms, pharmaceutical companies, research institutions applying AI/ML techniquesPharmaceutical, chemical, and materials industries conducting chemical research and development

Machine Learning Computational Chemists specialize in applying machine learning algorithms to chemical data, enhancing predictive models and simulations. Computational Chemists focus on traditional chemical modeling and simulations using computational methods. Both roles require strong chemistry backgrounds, but Machine Learning Computational Chemists emphasize data science and AI skills, while Computational Chemists focus on chemical theory and modeling techniques.

What are popular job titles related to Machine Learning Computational Chemistry jobs in Delaware?

For Machine Learning Computational Chemistry jobs in Delaware, the most frequently searched job titles are:

What job categories do people searching Machine Learning Computational Chemistry jobs in Delaware look for?

The top searched job categories for Machine Learning Computational Chemistry jobs in Delaware are:

Infographic showing various Machine Learning Computational Chemistry job openings in Delaware as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 24% Part Time, 1% Temporary, and 2% Contract. Highlights an 87% Physical, 3% Hybrid, and 10% Remote job distribution.

Data Domain Architect Lead

Wilmington, DE

JP Morgan Chase
Finance and Insurance • 10K+ employees

Full-time

Medical, Retirement

Re-posted 10 days ago


JPMorgan Chase & Co. rating

7.9

Company rating: 7.9 out of 10

Based on 500 frontline employees who took The Breakroom Quiz


Job description

Machine Learning and Artificial Intelligence play a critical role in transforming Consumer and Community Banking Operations. The ability to utilize data in meaningful ways allows us to develop solutions which both our customers and employees can benefit from. Customers expect tailored servicing and Chase is looking to deliver personalization to meet their needs. This is powered by high-quality annotated data and detailed annotation schemes that are the backbone of impactful  Artificial Intelligence/Machine Learning ( AI/ML)L algorithms and applications.

As a Data Domain Architect Lead within the Data  Annotation team , you will use your domain expertise and people-leading experience to partner your team closely with teams in Data Science, Analytics, and Engineering to develop machine learning solutions. This will involve the collection, curation, annotation, enrichment, and validation of data and the development of taxonomies and other linguistic resources to help train machine learning models, drive insight, analysis, and possible content creation.

Job responsibilities

  • Manage and coach a team of Machine Learning Data Domain analysts to support data annotation and label data/content using annotation tools and analysis

  • Partner with leads in Data Science, Engineering, and Analytics to develop strategies to optimize training data for machine learning models
  • Lead efforts to identify patterns and trends in conversational data through Natural Language Processing and/or other computational linguistic approaches
  • Collaborate with stakeholders on evaluating the quality of machine learning classification and other output
  • Actively contribute to the team's continuous learning mindset by bringing in new ideas and perspectives that stretch the thinking of the group

Required qualifications, capabilities, and skills

  • 6+ years of related experience in development of machine learning solutions
  • Familiar with industry annotation and labeling methods
  • Experience with various data modeling techniques and tools
  • Familiar with Finance and Banking products
  • Broad expertise in data technologies; i.e., data warehousing, data processing, data quality concepts, Business Intelligence tools and analytical tools, unstructured data, machine learning
  • Excellent analytical and problem-solving skills and the ability to pay close attention to detail
  • Experience using Python in working with and analyzing large real-world datasets
  • Working knowledge of information and data retrieval
  • Working knowledge of machine learning and artificial intelligence paradigms and libraries
  • Familiar with  Large Language Models (LLMs) and prompt engineering

Preferred qualifications, capabilities, and skills

  • Masters or PhD in a related field, or Bachelors 
  • Technical understanding of common relational database systems; i.e., Teradata and Oracle
  • Excellent command of the Structured Query Language (SQL)
  • Knowledge of SAS or Scala, and Python languages
  • Knowledge of Advanced Statistics
  • Advanced analytical thinking and problem-solving skills
  • Strong interpersonal & communication skills

Chase is a leading financial services firm, helping nearly half of America's households and small businesses achieve their financial goals through a broad range of financial products. Our mission is to create engaged, lifelong relationships and put our customers at the heart of everything we do. We also help small businesses, nonprofits and cities grow, delivering solutions to solve all their financial needs. 

We offer a competitive total rewards package including base salary determined based on the role, experience, skill set and location. Those in eligible roles may receive commission-based pay and/or discretionary incentive compensation, paid in the form of cash and/or forfeitable equity, awarded in recognition of individual achievements and contributions.  We also offer a range of benefits and programs to meet employee needs, based on eligibility. These benefits include comprehensive health care coverage, on-site health and wellness centers, a retirement savings plan, backup childcare, tuition reimbursement, mental health support, financial coaching and more. Additional details about total compensation and benefits will be provided during the hiring process. 

We recognize that our people are our strength and the diverse talents they bring to our global workforce are directly linked to our success. We are an equal opportunity employer and place a high value on diversity and inclusion at our company. We do not discriminate on the basis of any protected attribute, including race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, marital or veteran status, pregnancy or disability, or any other basis protected under applicable law. We also make reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as mental health or physical disability needs. Visit our FAQs for more information about requesting an accommodation.

Equal Opportunity Employer/Disability/Veterans

Our Consumer & Community Banking division serves our Chase customers through a range of financial services, including personal banking, credit cards, mortgages, auto financing, investment advice, small business loans and payment processing. We're proud to lead the U.S. in credit card sales and deposit growth and have the most-used digital solutions - all while ranking first in customer satisfaction.

The CCB Data & Analytics team responsibly leverages data across Chase to build competitive advantages for the businesses while providing value and protection for customers. The team encompasses a variety of disciplines from data governance and strategy to reporting, data science and machine learning. We have a strong partnership with Technology, which provides cutting edge data and analytics infrastructure. The team powers Chase with insights to create the best customer and business outcomes.

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