1

Machine Learning Computational Chemistry Jobs in Delaware

R&D Engineer

Wilmington, DE · On-site

$116K - $182K/yr

Most projects require mechanical, electrical and firmware engineers, as well as chemists and ... Material processing techniques such as precision machining, sheet metal, casting/molding, ceramics ...

R&D Engineer

Wilmington, DE · On-site

$116K - $182K/yr

Most projects require mechanical, electrical and firmware engineers, as well as chemists and ... Material processing techniques such as precision machining, sheet metal, casting/molding, ceramics ...

next page

Showing results 1-20

Machine Learning Computational Chemistry information

What is the difference between Machine Learning Computational Chemistry vs Computational Chemist?

AspectMachine Learning Computational ChemistryComputational Chemist
Required CredentialsAdvanced degrees in chemistry, computer science, or related fields; knowledge of machine learning and programmingDegree in chemistry, chemical engineering, or related fields; strong background in chemical theory and modeling
Work EnvironmentResearch labs, tech companies, academia; focus on algorithm development and data analysisLaboratories, research institutions, industry; focus on chemical modeling and simulation
Employer & Industry UsageTech firms, pharmaceutical companies, research institutions applying AI/ML techniquesPharmaceutical, chemical, and materials industries conducting chemical research and development

Machine Learning Computational Chemists specialize in applying machine learning algorithms to chemical data, enhancing predictive models and simulations. Computational Chemists focus on traditional chemical modeling and simulations using computational methods. Both roles require strong chemistry backgrounds, but Machine Learning Computational Chemists emphasize data science and AI skills, while Computational Chemists focus on chemical theory and modeling techniques.

What is machine learning computational chemistry?

Machine learning computational chemistry is a field that combines machine learning techniques with computational chemistry to accelerate the discovery and design of molecules and materials. By training algorithms on large datasets of chemical information, researchers can predict molecular properties, simulate chemical reactions, and optimize compounds more efficiently than traditional methods. This approach helps reduce the time and cost required for research in drug discovery, materials science, and related fields.

What are some common challenges faced by professionals working in Machine Learning Computational Chemistry roles?

One common challenge in Machine Learning Computational Chemistry roles is integrating large and often complex chemical datasets with appropriate machine learning models, which requires a solid understanding of both domains. Professionals may also encounter difficulties in ensuring that their models are both interpretable and generalizable to new data, as overfitting is a frequent issue. Additionally, collaboration with chemists and data scientists is essential, so clear communication across disciplines is key to success. Staying up to date with the latest developments in both computational chemistry and machine learning is crucial for ongoing professional growth.

What are the key skills and qualifications needed to thrive as a Machine Learning Computational Chemist, and why are they important?

To thrive as a Machine Learning Computational Chemist, you need a solid background in chemistry, mathematics, and computer science, typically supported by an advanced degree in computational chemistry, cheminformatics, or a related field. Proficiency with programming languages (such as Python), machine learning frameworks (like TensorFlow or PyTorch), and molecular modeling software is essential. Strong analytical thinking, problem-solving skills, and effective collaboration are key soft skills that help drive innovation and teamwork. These skills and qualifications are critical for developing accurate models, advancing research, and translating computational insights into real-world chemical solutions.
What are popular job titles related to Machine Learning Computational Chemistry jobs in Delaware? For Machine Learning Computational Chemistry jobs in Delaware, the most frequently searched job titles are:
What cities in Delaware are hiring for Machine Learning Computational Chemistry jobs? Cities in Delaware with the most Machine Learning Computational Chemistry job openings:
Infographic showing various Machine Learning Computational Chemistry job openings in Delaware as of May 2026, with employment types broken down into 1% Internship, 3% As Needed, 14% Full Time, 81% Part Time, and 1% Contract. Highlights an 84% Physical, 1% Hybrid, and 15% Remote job distribution.
Computational Linguist, Generative AI - Sr. Associate

Computational Linguist, Generative AI - Sr. Associate

JPMorgan Chase & Co

Wilmington, DE • Hybrid

Full-time

Medical, Retirement

Posted 21 days ago


JPMorgan Chase & Co. rating

8.1

Company rating: 8.1 out of 10

Based on 468 frontline employees who took The Breakroom Quiz

46th of 141 rated banks


Job description

We're looking for a versatile Computational Linguist to join our team focused on evaluating and supporting Generative and Agentic AI systems. This role combines linguistic expertise, data analysis, and hands-on experimentation with large language models.  
This role is ideal for someone who can move between qualitative language analysis and quantitative evaluation. You'll work cross-functionally with Machine Learning Engineers, Analytics team and annotators to design innovative, rigorous, and scalable evaluation processes for LLM-powered workflows.   


Core Responsibilities 
    Serve as a subject matter expert, engaging with various stakeholders throughout the product lifecycle, and maintain a strong understanding of the Chase Digital Assistant's model from both customer and technical perspectives. 
    Manage, monitor, and evaluate and version the Chase Digital Assistant's intent and entity taxonomy and the model training; Enforce taxonomy versioning practices to ensure traceability and rollback capability 
    Work closely on the adaptation to LLM-driven workflows, ensuring seamless integration of LLMs with existing conversational AI architectures and event tracking systems. 
    Implement and evolve metrics and KPIs across Model Correctness, Customer Experience, AI Assurance, and Business Metrics and ensure evaluation is transparent, repeatable, and release-decision-ready 
    Maintain established metrics and introduce new guardrail metrics for LLM and generative use cases 
    Manage full artifact suite for LLM models including  descriptions, prompts, evaluation rubrics, LLM-as-judge prompts, guidelines, calibration data, data statistics & reliability measures.  
    Apply ontology design principles to improve semantic reasoning and data integration aligned to business standards. 
    Design frameworks to incorporate knowledge graphs within classification and extraction model architectures. 
    Align knowledge models with RAG pipelines and agent orchestration to enhance AI functionality. 
    Work with data scientists, software engineers, and business stakeholders to translate requirements into robust solutions. 
    Identifying optimization opportunities across teams, supporting continuous improvement across model performance, data quality, and feature coverage for improving customer experience. 
Required Qualifications, Capabilities, and Skills 
    Master's degree in Computational Linguistics, NLP, Linguistics, or related field 
    2+ experience  in Computational Linguistics or NLP applied to chatbot or conversational AI development 
    Hands-on experience with Generative AI and Agentic AI frameworks and evaluation (e.g., AutoGen, LangGraph, CrewAI, Sierra) 
    Linguistic background in discourse & pragmatics 
    Advanced knowledge of conversational AI product development lifecycle - training, design, conversation analysis 
    Hands-on experience with LLM integration, prompt engineering, evaluation, and performance monitoring 
    Proficient in Python, Git, Linux, and Bash scripting 
    Fluent with NLP/data science libraries: pandas, numpy, scikit-learn, NLTK 
    Experience with transformer-based models (e.g., BERT, GPT) - fine-tuning and application 
    Experience with generative AI SDKs and frameworks (e.g., OpenAI, Google, Anthropic, LangChain) 
    Comfortable with JSONL, CSV, and Jupyter notebook workflows 
    Experience with ontologies/taxonomies and knowledge graphs 
    Solid understanding of evaluation methodologies including human-AI comparison and red teaming 
    Direct experience with financial institutions, financial products, and customer-facing queries 
    Chase customer service experience highly desirable 
    Strong written communication for documenting experiments, results, and processes

Preferred Qualifications 
    Experience with hybrid conversational architectures, generative AI, and LLM-driven flow design 
    Familiarity with LLM safety, bias, and compliance 
    Demonstrated success in a highly matrixed organization 
    Awareness of current GenAI trends and evaluation challenges in subjective NLP tasks 
    Solve the cold start problem via synthetic data generation for new intents, flows, and low-resource scenarios. 

Chase is a leading financial services firm, helping nearly half of America's households and small businesses achieve their financial goals through a broad range of financial products. Our mission is to create engaged, lifelong relationships and put our customers at the heart of everything we do. We also help small businesses, nonprofits and cities grow, delivering solutions to solve all their financial needs. 

We offer a competitive total rewards package including base salary determined based on the role, experience, skill set and location. Those in eligible roles may receive commission-based pay and/or discretionary incentive compensation, paid in the form of cash and/or forfeitable equity, awarded in recognition of individual achievements and contributions.  We also offer a range of benefits and programs to meet employee needs, based on eligibility. These benefits include comprehensive health care coverage, on-site health and wellness centers, a retirement savings plan, backup childcare, tuition reimbursement, mental health support, financial coaching and more. Additional details about total compensation and benefits will be provided during the hiring process. 

We recognize that our people are our strength and the diverse talents they bring to our global workforce are directly linked to our success. We are an equal opportunity employer and place a high value on diversity and inclusion at our company. We do not discriminate on the basis of any protected attribute, including race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, marital or veteran status, pregnancy or disability, or any other basis protected under applicable law. We also make reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as mental health or physical disability needs. Visit our FAQs for more information about requesting an accommodation.

Equal Opportunity Employer/Disability/Veterans

Our Consumer & Community Banking division serves our Chase customers through a range of financial services, including personal banking, credit cards, mortgages, auto financing, investment advice, small business loans and payment processing. We're proud to lead the U.S. in credit card sales and deposit growth and have the most-used digital solutions - all while ranking first in customer satisfaction.

The CCB Data & Analytics team responsibly leverages data across Chase to build competitive advantages for the businesses while providing value and protection for customers. The team encompasses a variety of disciplines from data governance and strategy to reporting, data science and machine learning. We have a strong partnership with Technology, which provides cutting edge data and analytics infrastructure. The team powers Chase with insights to create the best customer and business outcomes.

What JPMorgan Chase & Co. employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom