Titusville, NJ · On-site
$20 - $30/hr
Operate and maintain LC-MS systems (Thermo LTQ, Thermo Orbitrap) for in-process and final QC of ... Familiarity with lipid nanoparticle (LNP) formulations of mRNA . * Strong data analysis ...
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Titusville, NJ · On-site
$20 - $30/hr
Operate and maintain LC-MS systems (Thermo LTQ, Thermo Orbitrap) for in-process and final QC of ... Familiarity with lipid nanoparticle (LNP) formulations of mRNA . * Strong data analysis ...
| Aspect | Lnp Process Development | Lnp Manufacturing Specialist |
|---|---|---|
| Credentials | Bachelor's/Master's in Pharmaceutical Sciences or Chemical Engineering | Bachelor's in related field, with experience in manufacturing |
| Work Environment | Research labs, development facilities | Production lines, manufacturing plants |
| Industry Usage | Designing and optimizing processes | Executing and monitoring manufacturing processes |
While both roles work within the pharmaceutical industry, Lnp Process Development focuses on creating and refining lipid nanoparticle processes, whereas Lnp Manufacturing Specialist handles the production and quality control of these nanoparticles on the manufacturing floor. The roles are complementary but differ mainly in scope and environment.
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$20 - $30/hr
Contractor
Re-posted 3 days ago
Location: La Jolla, California (Onsite – 100% required, no remote option)
About the RoleWe are seeking a Scientist I with expertise in oligonucleotide analytics to join our team in La Jolla, CA. This role is 100% onsite and will focus on the characterization, optimization, and QC of siRNA and other therapeutic oligonucleotides using advanced analytical chemistry techniques.
The ideal candidate has a PhD in Analytical Chemistry or related field, 1–3 years of relevant industry experience, and hands-on expertise with LC-MS (Thermo LTQ, Thermo Orbitrap), chromatography, and oligonucleotide characterization.
Operate and maintain LC-MS systems (Thermo LTQ, Thermo Orbitrap) for in-process and final QC of oligonucleotides (siRNA, ASO).
Optimize and improve analytical methods for novel oligonucleotide synthesis projects.
Apply HPLC (denaturing, non-denaturing, RP-IP, SEC, ion-exchange) and LC-MS for nucleic acid and lipid analysis (GalNAc, cholesterol, C16 phosphoramidites, LNPs).
Establish and automate high-throughput analytical workflows to support discovery and preclinical programs.
Conduct QC testing of oligonucleotides and assist in method development for assay requests from biology teams.
Present technical data and project updates at team and departmental meetings.
Ensure lab supplies are stocked and maintain high productivity in a fast-paced lab environment.
Ph.D. in Analytical Chemistry or related discipline with 1–3 years of relevant lab/research experience.
Proven expertise in oligonucleotide and/or nucleoside/nucleotide characterization.
Hands-on experience with chromatography techniques (HPLC, LC-MS, SEC, ion-exchange).
Direct experience analyzing siRNA, ASO, and oligonucleotide modifications.
Familiarity with lipid nanoparticle (LNP) formulations of mRNA.
Strong data analysis, troubleshooting, and method optimization skills.
LC-MS Operation (Thermo LTQ, Orbitrap LC/MS)
Analytical Method Development & Optimization
High-Throughput Analytics and Automation
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Formed in 1996, Infobahn Softworld is a leading Technology and Professional Services Company. For many years we have successfully served the technology needs of several customers from diverse industries and locations throughout North America. Infobahn Softworld has a reputation for addressing its clients’ complex challenges with business understanding and innovative technical solutions. Infobahn specializes in full lifecycle project efforts conducted in strategic partnership with some of the world’s most prominent companies.
Recruiting and staffing services
201 - 500 Employees
San Jose, CA, US
1996