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Lead Ai Developer Jobs (NOW HIRING)

Lead AI Engineer

Sleepy Hollow, NY · On-site

$108K - $142K/yr

Lead AI Engineer Department: Digital Transformation - AI Strategy & Execution Location: Sleepy Hollow, New York Employment Type: Full-Time Experience Required: 7-10 Years About Regeneron Regeneron is ...

Lead AI Engineer

Tarrytown, NY · On-site

$108K - $143K/yr

Lead AI Engineer Department: Digital Transformation - AI Strategy & Execution Location: Sleepy Hollow, New York Employment Type: Full-Time Experience Required: 7-10 Years About Regeneron Regeneron is ...

Lead AI Engineer

Denver, CO · On-site

$147K - $202K/yr

Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered. A day in the life The Lead AI Engineer builds ...

Lead AI Engineer

Dallas, TX · On-site

$147K - $202K/yr

Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered. A day in the life The Lead AI Engineer builds ...

Lead AI Engineer

San Francisco, CA · On-site

$147K - $202K/yr

Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered. A day in the life The Lead AI Engineer builds ...

Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered. A day in the life The Lead AI Engineer builds ...

Lead AI Engineer

Denver, CO · On-site

$147K - $202K/yr

Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered. A day in the life The Lead AI Engineer builds ...

Lead AI Engineer

Tarrytown, NY · On-site

$108K - $142K/yr

Lead AI Engineer Department: Digital Transformation - AI Strategy & Execution Location: Sleepy Hollow, New York Employment Type: Full-Time Experience Required: 7-10 Years About Regeneron Regeneron is ...

Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered. A day in the life The Lead AI Engineer builds ...

Lead AI Engineer

$104K - $138K/yr

The Lead AI Engineer will play a key role in establishing and scaling Accurate Background's emerging AI capabilities as part of a new team focused on building reusable AI platforms, AI engineering ...

Lead AI Engineer

Phoenix, AZ · On-site

$147K - $202K/yr

Job Title Lead AI Engineer Company Prologis Title Lead AI Engineer Location: Denver, CO; San Francisco, CA; Phoenix, AZ; Chicago, IL; or Dallas, TX. Other Prologis office locations may be considered.

Lead AI Engineer

Birmingham, MI · On-site

$97K - $128K/yr

Lead AI Engineer Location :Hybrid, United States Employment Type :Full-Time Benefits Offered :Vision, Medical, Life, Dental, 401K Gross Annual Base Salary :USD 151,000 - 196,000 Additional variable ...

Lead AI Engineer

Chicago, IL · On-site

$105K - $139K/yr

Lead AI Engineer Location :  Hybrid, United States Employment Type : Full-Time Benefits Offered : Vision, Medical, Life, Dental, 401K Gross Annual Base Salary : USD 151,000 - 196,000 ...

Lead AI Engineer

Irvine, CA · On-site

$110K - $144K/yr

The Lead AI Engineer will play a key role in establishing and scaling Accurate Background's emerging AI capabilities as part of a new team focused on building reusable AI platforms, AI engineering ...

Lead AI Engineer

Chicago, IL · On-site

$105K - $139K/yr

Description Lead AI Engineer Location : Hybrid, United States Employment Type : Full-Time Benefits Offered : Vision, Medical, Life, Dental, 401K Gross Annual Base Salary : USD 151,000 - 196,000 ...

Lead AI Engineer

Birmingham, MI · On-site

$97K - $128K/yr

Description Lead AI Engineer Location : Hybrid, United States Employment Type : Full-Time Benefits Offered : Vision, Medical, Life, Dental, 401K Gross Annual Base Salary : USD 151,000 - 196,000 ...

Lead AI Engineer

Fort Lauderdale, FL · On-site

$98K - $129K/yr

Lead AI Engineer Location :  Hybrid, United States Employment Type : Full-Time Benefits Offered : Vision, Medical, Life, Dental, 401K Gross Annual Base Salary : USD 151,000 - 196,000 ...

Lead AI Engineer

Manhattan, NY · On-site

$112K - $148K/yr

Description Lead AI Engineer Location : Hybrid, United States Employment Type : Full-Time Benefits Offered : Vision, Medical, Life, Dental, 401K Gross Annual Base Salary : USD 151,000 - 196,000 ...

Showing results 21-40

Lead Ai Developer information

See salary details

$10

$64

$88

How much do lead ai developer jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for lead ai developer in the United States is $64.33, according to ZipRecruiter salary data. Most workers in this role earn between $56.73 and $74.28 per hour, depending on experience, location, and employer.

What is a Lead AI Developer?

A Lead AI Developer is a senior-level professional responsible for overseeing the design, development, and implementation of artificial intelligence solutions within an organization. They lead a team of AI engineers and data scientists, guiding the technical strategy and architecture of AI projects. Their role often involves collaborating with stakeholders to understand business needs, setting project goals, and ensuring that AI systems are scalable, reliable, and ethical. Lead AI Developers also stay up-to-date with the latest advancements in AI technology and best practices to drive innovation within their teams.

What are the key skills and qualifications needed to thrive as a Lead AI Developer?

To thrive as a Lead AI Developer, you need advanced expertise in machine learning, deep learning, and programming languages like Python or Java, usually backed by a degree in computer science or a related field. Familiarity with AI frameworks (such as TensorFlow, PyTorch), cloud platforms, and experience with data engineering tools and model deployment is essential. Leadership, problem-solving, and strong collaboration skills help you manage teams and communicate complex technical ideas effectively. These capabilities are crucial for designing innovative AI solutions, leading technical teams, and driving successful project delivery.

How does a Lead AI Developer typically collaborate with cross-functional teams during a project?

As a Lead AI Developer, you’ll frequently work alongside data scientists, software engineers, product managers, and business stakeholders to ensure AI solutions align with organizational goals. Collaboration often involves translating technical AI concepts into actionable plans, guiding team members through implementation challenges, and facilitating communication between technical and non-technical team members. Effective leadership in this role means fostering an environment where feedback is encouraged and project milestones are clearly communicated, ultimately resulting in efficient, innovative AI product development.

What is the difference between Lead Ai Developer vs Data Scientist?

AspectLead Ai DeveloperData Scientist
Required CredentialsBachelor's/Master's in CS, AI, or related; experience with AI frameworksBachelor's/Master's in CS, Statistics, or related; strong analytical skills
Work EnvironmentDevelops AI models, leads AI projects, collaborates with engineering teamsAnalyzes data, builds predictive models, interprets complex datasets
Industry UsageUsed in tech companies, AI startups, R&D departmentsCommon in finance, healthcare, marketing, and research sectors

The main difference is that a Lead Ai Developer focuses on designing and leading AI development projects, while a Data Scientist emphasizes analyzing data and building predictive models. Both roles require strong technical skills and often overlap, but their primary responsibilities and work focus differ.

What cities are hiring for Lead Ai Developer jobs?

Cities with the most Lead Ai Developer job openings:

What states have the most Lead Ai Developer jobs?

States with the most job openings for Lead Ai Developer jobs include:

What are popular job titles related to Lead Ai Developer jobs?

For Lead Ai Developer jobs, the most frequently searched job titles are:

Infographic showing various Lead Ai Developer job openings in the United States as of September 2026, with employment types broken down into 56% Full Time, and 44% Contract. Highlights an 81% In-person, and 19% Remote job distribution, with an average salary of $133,813 per year, or $64.3 per hour.

Lead AI Engineer

Sleepy Hollow, NY • On-site

Regeneron Pharmaceuticals
Biotechnology Research and Development • 5 - 10K employees

$108K - $142K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 17 days ago


Key responsibilities

  • Lead end-to-end design, development, and deployment of enterprise AI applications and LLM-powered systems.

  • Design and build AI Agents and autonomous systems using frameworks such as LangChain, LangGraph, Strands, and CrewAI.

  • Lead, mentor, and manage a team of AI engineers, conduct code reviews, and set technical standards.


Regeneron rating

8.6

Company rating: 8.6 out of 10

Based on 45 frontline employees who took The Breakroom Quiz


Job description

Job Title: Lead AI Engineer

Department: Digital Transformation - AI Strategy & Execution

Location: Sleepy Hollow, New York

Employment Type: Full-Time

Experience Required: 7-10 Years

About Regeneron

Regeneron is a leading biotechnology company headquartered in Tarrytown, New York, renowned for its innovative research and development of life-changing therapies. With a strong focus on ophthalmology, oncology, inflammation, cardiovascular diseases, and infectious diseases, Regeneron has brought groundbreaking medicines to market - including EYLEA and the REGEN-COV monoclonal antibody cocktail. Our commitment to scientific excellence, cutting-edge technology, and patient impact has positioned Regeneron as a global leader in biotechnology.

Position Overview

Regeneron is seeking an experienced Lead AI Engineer to serve as a technical leader within the AI Strategy & Execution organization. In this role, you will architect and deliver enterprise-scale AI capabilities - spanning intelligent agents, LLM-powered applications, and AI platform services - that accelerate drug discovery, clinical research, and enterprise productivity. You will lead a team of engineers, drive cross-functional collaboration, and communicate AI strategy to senior stakeholders, all while maintaining a strong hands-on presence in Python development and AI systems design.

Key ResponsibilitiesAI Engineering & Intelligent Systems
  • Lead end-to-end design, development, and deployment of enterprise AI applications and LLM-powered systems, ensuring production-grade quality, security, and scalability.
  • Design and build AI Agents and autonomous systems using agentic frameworks including LangChain, LangGraph, Strands, and CrewAI, applying ReAct, tool-use, planning, and memory management patterns.
  • Develop and operate MCP (Model Context Protocol) servers for standardized, secure integration between AI agents and enterprise data sources.
  • Apply advanced LLM techniques - prompt engineering, fine-tuning, and retrieval-augmented generation (RAG) - to build intelligent, context-aware applications.
  • Architect and manage vector database solutions (Milvus DB preferred) supporting semantic search, knowledge retrieval, and RAG pipelines.
  • Architect RESTful APIs that expose AI capabilities to internal platforms and downstream business applications.
LLM & AI Platform Management
  • Administer and continuously evolve the enterprise LLM and AI Gateway platform, including model routing, access controls, rate limiting, usage observability, and multi-model orchestration.
  • Evaluate and onboard new foundation models (OpenAI, Anthropic, AWS Bedrock, and others) in alignment with enterprise security and compliance standards.
Technical Leadership & Team Management
  • Lead, mentor, and manage a team of AI engineers, conducting code reviews, setting technical standards, and fostering a culture of engineering excellence.
  • Contribute to the organization's AI roadmap through architectural design reviews, technical strategy, and proof-of-concept development.
  • Troubleshoot complex issues across AI model serving, APIs, and platform layers.
Cross-Functional Collaboration & Stakeholder Engagement
  • Partner with business units, data scientists, and clinical research teams to identify AI opportunities and translate them into scalable technical solutions.
  • Serve as the primary technical point of contact for enterprise AI platform discussions, presenting findings and recommendations to senior leadership.
  • Engage with external vendors, cloud providers, and AI research organizations to evaluate and integrate emerging capabilities.
Requirements & QualificationsEducation
  • Bachelor's, Master's, or Ph.D. in Computer Science, Computer Engineering, Artificial Intelligence or a related technical field.
Experience
  • 7-10 years of progressive software and AI engineering experience, with at least 3 years in a technical lead or senior individual contributor role.
  • Expert-level Python development skills, including production REST API development with FastAPI.
  • Proven hands-on experience building AI Agents, MCP Servers, and LLM-powered applications using frameworks such as LangChain, LangGraph, Strands, or CrewAI.
  • Hands-on experience with vector databases (Milvus DB preferred) for RAG and semantic search pipelines.
  • Experience administering LLM API gateway platforms, including model routing, observability, access governance, and multi-model orchestration.
  • Experience with foundation models from OpenAI, Anthropic, AWS Bedrock, and other major providers.
  • Working knowledge of AWS cloud services relevant to AI workloads (SageMaker, Bedrock, EKS, Lambda, S3); Kubernetes and CI/CD experience is a plus.
  • Experience in the biotechnology, pharmaceutical, or healthcare industry preferred.
Technical Competencies
  • Programming: Python (expert-level).
  • AI Frameworks & Runtimes: LangChain, LangGraph, Strands, CrewAI; AWS Bedrock AgentCore.
  • LLM Techniques: Prompt engineering, fine-tuning, RAG, vector databases (Milvus DB preferred).
  • AI Platform: LLM Gateway management, model routing, multi-model orchestration, TensorFlow, PyTorch.
  • API Development: RESTful API design, FastAPI, OpenAPI/Swagger.
  • Cloud & Infrastructure (supporting): AWS (SageMaker, Bedrock, EKS, Lambda, S3), Kubernetes, Docker, Terraform, CI/CD pipelines.
  • Data & Analytics: Databricks, Dataiku, Postgres, Redis, NoSQL databases.
  • Observability: Monitoring, logging, and distributed tracing for AI workloads.
Certifications

Required:

  • AWS Certified Machine Learning - Specialty

Nice to Have:

  • AWS Certified Solutions Architect - Professional
  • Certified Kubernetes Administrator (CKA)
Soft Skills & Leadership
  • Exceptional communication skills with the ability to present AI concepts to both engineering teams and executive stakeholders.
  • Proven track record of leading engineering teams and managing delivery across cross-functional groups.
  • Strong problem-solving mindset with a bias toward pragmatic, production-ready AI solutions.
  • Collaborative and proactive in engaging with business units, compliance, and external partners.

Joining Regeneron as a Lead AI Engineer offers a unique opportunity to shape enterprise AI strategy, build transformative platforms, and make a meaningful impact on the advancement of global healthcare. If you are a driven technical leader with deep expertise in AI systems and a passion for innovation in a regulated environment, we invite you to apply.Please copy and paste the desired job description for this role here. If you need a copy of an existing job description please reach out to TA or work with your HR Business Partner to develop one for a new role.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.


Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.


As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.


For jobs in Canada: this posting is for an existing position.


Salary Range (annually)

$109,900.00 - $179,300.00

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