... physical properties of the API required for the drug product and designing crystallization ... and mass transfer, thermodynamics, crystallization and precipitation kinetics, solid-liquid ...
... physical properties of the API required for the drug product and designing crystallization ... and mass transfer, thermodynamics, crystallization and precipitation kinetics, solid-liquid ...
Process Engineer
Shirley, IN · On-site
... metallurgical properties * Interface with metallurgical lab for chemistry verification ... internship or co-op experience in a foundry environment considered) * Basic understanding of ...
Process Engineer
Shirley, IN · On-site
... metallurgical properties * Interface with metallurgical lab for chemistry verification ... internship or co-op experience in a foundry environment considered) * Basic understanding of ...
Process Engineer
Shirley, IN · On-site
$65K - $75K/yr
... metallurgical properties * Interface with metallurgical lab for chemistry verification ... internship or co-op experience in a foundry environment considered) * Basic understanding of ...
Quick apply
Process Engineer
Shirley, IN · On-site
$65K - $75K/yr
... metallurgical properties * Interface with metallurgical lab for chemistry verification ... internship or co-op experience in a foundry environment considered) * Basic understanding of ...
Senior Process Engineer
Edwardsport, IN · On-site
$98K - $126K/yr
A Senior Process Engineer is responsible for daily oversight of process equipment with emphasis on ... Proficient understanding of thermodynamic principles, heat and mass balances, and steam properties.
Senior Process Engineer
Edwardsport, IN · On-site
$98K - $126K/yr
A Senior Process Engineer is responsible for daily oversight of process equipment with emphasis on ... Proficient understanding of thermodynamic principles, heat and mass balances, and steam properties.
Senior Process Engineer
Edwardsport, IN · On-site
$110 - $160/hr
A Senior Process Engineer is responsible for daily oversight of process equipment with emphasis on ... Proficient understanding of thermodynamic principles, heat and mass balances, and steam properties.
Senior Process Engineer
Edwardsport, IN · On-site
$110 - $160/hr
A Senior Process Engineer is responsible for daily oversight of process equipment with emphasis on ... Proficient understanding of thermodynamic principles, heat and mass balances, and steam properties.
Thermal Systems Engineer
Bloomington, IN · On-site
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
Quick apply
Thermal Systems Engineer
Bloomington, IN · On-site
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
Thermal Systems Engineer
Bloomington, IN · On-site
$90 - $130/hr
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
Thermal Systems Engineer
Bloomington, IN · On-site
$90 - $130/hr
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
New
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
New
... properties, internal ballistics pressure-time curves, and aerodynamic flight loads. * Execute ... Conduct trade studies and optimization to minimize structural mass while maintaining required ...
New
... properties, internal ballistics pressure-time curves, and aerodynamic flight loads. * Execute ... Conduct trade studies and optimization to minimize structural mass while maintaining required ...
New
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
New
Conduct trade studies and design optimization to balance TPS mass, thermal margin, structural ... Correlate analytical thermal models against measured test data to refine material property decks ...
New
Knowledge and/or experience with security tools and concepts, programming languages, malware ... the property of Elevance Health. Who We Are Elevance Health is a health company dedicated to ...
Knowledge and/or experience with security tools and concepts, programming languages, malware ... the property of Elevance Health. Who We Are Elevance Health is a health company dedicated to ...
... properties, internal ballistics pressure-time curves, and aerodynamic flight loads. * Execute ... Conduct trade studies and optimization to minimize structural mass while maintaining required ...
New
... properties, internal ballistics pressure-time curves, and aerodynamic flight loads. * Execute ... Conduct trade studies and optimization to minimize structural mass while maintaining required ...
New
$13 - $17.50/hr
Supporting topographic and engineering surveys. * Operating survey equipment and GPS data ... Recording field measurements and identifying property boundaries. * Assisting with utility locating ...
$13 - $17.50/hr
Supporting topographic and engineering surveys. * Operating survey equipment and GPS data ... Recording field measurements and identifying property boundaries. * Assisting with utility locating ...
PE Engineer I, IPM
Greenfield, IN · On-site
... requirements for mass production. This will be a fully onsite role to best support our ... No direct reports * Guide and support other engineers, interns, EIT's, TS's, MA's, and TA ...
PE Engineer I, IPM
Greenfield, IN · On-site
... requirements for mass production. This will be a fully onsite role to best support our ... No direct reports * Guide and support other engineers, interns, EIT's, TS's, MA's, and TA ...
PE Engineer I, IPM
Greenfield, IN · On-site
... requirements for mass production. This will be a fully onsite role to best support our ... No direct reports * Guide and support other engineers, interns, EIT's, TS's, MA's, and TA ...
PE Engineer I, IPM
Greenfield, IN · On-site
... requirements for mass production. This will be a fully onsite role to best support our ... No direct reports * Guide and support other engineers, interns, EIT's, TS's, MA's, and TA ...
NCAA Postgraduate Internships
Indianapolis, IN · On-site
$14.75 - $19/hr
Launch your career in collegiate athletics through the NCAA Postgraduate Internship Program ... Legal Affairs - Support the NCAA's office of legal affairs across contracts, intellectual property ...
NCAA Postgraduate Internships
Indianapolis, IN · On-site
$14.75 - $19/hr
Launch your career in collegiate athletics through the NCAA Postgraduate Internship Program ... Legal Affairs - Support the NCAA's office of legal affairs across contracts, intellectual property ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Indianapolis, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Indianapolis, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Valparaiso, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Valparaiso, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Westfield, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Westfield, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Westfield, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
Returning Intern Engineer - Summer 2027 - Great Lakes Division (For Current/Former HNTB Interns O...
Westfield, IN · On-site
$23.18 - $34.76/hr
This position is for current/former HNTB Interns only. What You'll Do: * Assists engineer teams in ... property of HNTB. HNTB will have the right to hire that applicant at its discretion and without any ...
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Engineer - Drug Substance Synthetic Molecule Design and Development
Indianapolis, IN
Full-time
Medical, Dental, Vision, Life, Retirement, PTO
Posted 12 days ago
Eli Lilly and Company rating
8.9
Based on 64 frontline employees who took The Breakroom Quiz
9th of 86 rated pharmaceutical
Job description
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work-but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
Synthetic Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre-clinical phases through commercialization of drug substances and drug products. Our scientists and engineers develop key technical and business solutions across the portfolio using their deep technical expertise to accelerate testing of the clinical hypothesis and overall drug development. SMDD delivers on these responsibilities by recognizing diverse talent and cultures are necessary to bring the next generation of life changing medicines to patients.
Our team is looking for creative and energetic candidates to facilitate unit operation development and process optimization of synthetic drug candidates to support clinical trials, regulatory submission, and product commercialization. The position presents an opportunity to work on dynamic teams comprised of process chemists, analytical chemists, formulation scientists, and engineers.
Position Responsibilities
- Generate process design and unit operation knowledge based on engineering principles for small molecules, and other emerging therapeutic modalities.
- Ensure successful scale-up of processes through fundamental engineering principles and equipment knowledge.
- Design and execute laboratory experiments, including manual and automated high- and low-throughput reactors, in support of crystallization process design and optimization.
- Develop drug substance processes and manufacturing technologies, with a focus on defining the physical properties of the API required for the drug product and designing crystallization processes to fulfill physical property and chemical purity requirements.
- Leverage and develop process analytical technology (PAT), continuous processing, mechanistic models, and novel formulation platforms to develop well-understood and robust crystallization processes capable of enhancing or tailoring API physical properties.
- Apply fundamental engineering and business principles to design and characterize synthetic processes. Use numerical engineering modeling tools to characterize reaction kinetics, reaction mechanisms, and process separations.
- Engage in generating creative solutions for improving existing processes and the creation of novel ones.
- Transfer process technical information to internal and external manufacturing sites. Provide technical oversight to external collaboration partners for laboratory and manufacturing activities.
- Author and maintain documentation such as laboratory notebooks and technical reports.
- Design effective and efficient process and equipment flow strategies, ensuring equipment is selected which is suitable and appropriate for its intended use, given the specific needs of the process.
- Stay informed about new technology and best practices. Propose, justify, evaluate, and implement new equipment, processing techniques, and technologies.
- Utilize technology to improve safety, quality, and productivity, both in development and manufacturing.
- Publish and share original research externally through peer-reviewed articles and conferences.
Minimum Qualifications:
- B.S or M.S. in chemical engineering or closely related engineering field.
- Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1
Additional Skills/Preferences
- Strong technical skills in synthetic organic chemistry with experience as a hands-on technical contributor in a laboratory environment.
- Utilization of chemical engineering fundamentals towards crystallization process design: heat and mass transfer, thermodynamics, crystallization and precipitation kinetics, solid-liquid separations, drying, particle size reduction (milling), mixing theory, and experimental design.
- Experience with online and offline analytical techniques and PAT such as image analysis tools, IR, Raman, FBRM, and solid-state characterization techniques such as XRPD, DSC, TGA, particle size analysis, and microscopy.
- Demonstrated problem solving skills.
- Strong verbal and written communication skills and ability to collaborate in a team environment.
- Ability to prioritize multiple activities and handle ambiguity.
Additional Information
- Travel: 0 to 10%.
- Location: Indianapolis, IN; Lilly Technology Center - North (LTC-N)
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$66,000 - $171,600Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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About Eli Lilly
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Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.
Industry
Pharmaceutical product wholesalers
Company size
10,000+ Employees
Headquarters location
Indianapolis, IN, US
Year founded
1876