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Internship Downstream Process Development Scientist Jobs in San Rafael, CA

DutchTech

Analytical Scientist I

Emeryville, CA · On-site

$120 - $140/hr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R& ... and downstream process development. * Execute, summarize, and interpret routine and complex ...

Prolific Machines

Analytical Scientist I

Emeryville, CA · On-site

$120K - $140K/yr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R& ... and downstream process development. * Execute, summarize, and interpret routine and complex ...

Prolific Machines

Analytical Scientist I

Emeryville, CA · On-site

$120K - $140K/yr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R& ... and downstream process development. * Execute, summarize, and interpret routine and complex ...

Prolific Machines

Analytical Scientist I

Emeryville, CA · On-site

$120K - $140K/yr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R& ... and downstream process development. * Execute, summarize, and interpret routine and complex ...

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All JobsDownstream Process Development Scientist JobsInternship Downstream Process Development Scientist JobsInternship Downstream Process Development Scientist Jobs in San Rafael, CA

Internship Downstream Process Development Scientist information

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How much do internship downstream process development scientist jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for internship downstream process development scientist in San Rafael, CA is $43.10, according to ZipRecruiter salary data. Most workers in this role earn between $31.63 and $51.44 per hour, depending on experience, location, and employer.

What does an internship downstream process development scientist do?

An Internship Downstream Process Development Scientist works in the biopharmaceutical industry, assisting with the development and optimization of processes that purify biological products such as proteins, antibodies, or vaccines after they are produced by cells. Their role often involves supporting laboratory experiments, analyzing samples, and documenting results to improve the efficiency and scalability of downstream processes like filtration and chromatography. Interns in this position gain hands-on experience with cutting-edge technologies and learn about regulatory requirements and industry standards. This role helps prepare students or recent graduates for a career in process development or biomanufacturing.

What types of projects and responsibilities can an internship downstream process development scientist expect to work on?

As an Internship Downstream Process Development Scientist, you can expect to be involved in hands-on laboratory work focusing on the purification and characterization of biopharmaceutical products. Typical responsibilities include preparing buffer solutions, operating chromatography and filtration systems, analyzing samples using various analytical techniques, and documenting experimental results. Interns often collaborate with experienced scientists and engineers, contributing to process optimization and troubleshooting. The role provides valuable exposure to industry-standard procedures and the opportunity to develop technical skills in a team-oriented environment.

What are the key skills and qualifications needed to thrive as an internship downstream process development scientist, and why are they important?

To thrive as an Internship Downstream Process Development Scientist, you need foundational knowledge in biochemistry, molecular biology, or chemical engineering, often supported by ongoing or recent enrollment in a relevant degree program. Familiarity with laboratory techniques such as chromatography, filtration, and analytical instruments, as well as experience with lab management software, is typically expected. Attention to detail, problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills and qualifications are crucial for conducting reliable experiments, analyzing data, and contributing to the optimization of bioprocesses in a collaborative research environment.

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Internship Downstream Process Development Scientist jobs near you
Infographic showing various Internship Downstream Process Development Scientist job openings in San Rafael, CA as of July 2026, with employment types broken down into 1% As Needed, 77% Full Time, 18% Part Time, and 4% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $89,645 per year, or $43.1 per hour.

Principal Scientist, Commercial and Late-Stage Purification Process Development

Denali Therapeutics

South San Francisco, CA • On-site

$159K - $207K/yr

Full-time

Medical, Retirement

Re-posted yesterday

Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
This position is responsible for driving downstream technical activities for commercial and late-stage process development for Denali's commercial and near-commercial biologics portfolio.
Key Accountabilities/Core Job Responsibilities:
  • Serve as downstream purification technical lead for commercial manufacturing including continued process verification, investigations, deviation support, and cross-site alignment.
  • Support lifecycle management activities for commercial products, including process improvements, tech transfer validation activities, local and cross-site change management, regulatory filing updates (CBE, PAS, Ex-US expansion), and responses to health authority questions.
  • Drive technical continuity and alignment across CDMO and internal manufacturing sites by ensuring process understanding, lessons learned and technical decisions are consistently captured and applied.
  • Design, oversee, and interpret small-scale process development studies that inform large-scale manufacturing decisions, support root-cause investigations, and enable lifecycle improvements.
  • Build and maintain technical risk assessments (e.g., FMEA) and process history files to support robust commercial manufacturing and future late-stage programs.
  • Support the incoming late-stage process development pipeline and commercial programs by applying best practices, platform knowledge, and prior manufacturing experience while contributing to standardization of lifecycle management practices.

Qualifications/Skills:
  • Typically requires a PhD in Biology, Biochemistry, Chemical Engineering, or a related scientific discipline, plus 10+ years of related work experience.
  • Strong experience with commercial process support and technology transfers, downstream purification process characterization, and process validation.
  • Experience managing post-approval changes as a technical SME in collaboration with site, regulatory, supply chain and quality.
  • Experience reviewing batch records, supporting deviation investigations, and assessing process performance during manufacturing campaigns.
  • Proven track record of representing bioprocess functions in cross-functional teams and working effectively with CDMOs.
  • Broad experience in process characterization, design of experiments, and analytics.
  • Experience developing downstream purification processes to support early- or late-stage clinical production.
  • Expertise in AKTA protein purification systems, antibody characterization methods, and other biophysical techniques.
  • Excellent critical thinking, scientific problem-solving, and communication skills
  • Familiarity with BLA authoring and post-approval regulatory support is preferred.

Salary Range: $159,000.00 to $207,000.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers
This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

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