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Infrastructure Building Jobs in Pennsylvania (NOW HIRING)

Seakeeper

Head of Infrastructure & Security

Leesport, PA · On-site

Building organizational capability while reducing key-person dependencies Managing Technology Investments * Owning infrastructure and security budgets, vendor relationships, licensing strategies, and ...

JLL

Building Engineer

Philadelphia, PA

As a Building Engineer at JLL, you will support the safe, reliable, and efficient operation of building systems and facility infrastructure. This role is responsible for performing preventive ...

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Infrastructure Building information

What is an infrastructure building job?

Infrastructure building jobs involve the planning, design, construction, and maintenance of essential public systems and facilities, such as roads, bridges, water supply, power grids, and telecommunications. These roles can include engineers, construction workers, project managers, and inspectors, all working together to create and sustain the foundational structures of a community or nation. The goal of infrastructure building is to support economic growth, public safety, and quality of life by ensuring that critical services and systems are reliable and efficient.

What are some common challenges faced by professionals working in infrastructure building projects?

Professionals in infrastructure building often encounter challenges such as coordinating multidisciplinary teams, adhering to tight project deadlines, and ensuring compliance with regulatory requirements. Unexpected issues like weather delays, supply chain disruptions, and changes in project scope can also arise, requiring adaptability and problem-solving skills. Collaborating effectively with engineers, contractors, and government officials is essential to keep projects on track and within budget.

What are the key skills and qualifications needed to thrive as an infrastructure building professional, and why are they important?

To excel in Infrastructure Building, you need expertise in civil engineering principles, construction management, and project planning, often backed by a relevant degree or certification such as PMP or PE. Familiarity with design software like AutoCAD, project management tools, and compliance with safety regulations is essential. Strong leadership, problem-solving abilities, and effective communication distinguish top professionals in this field. These skills and qualifications ensure infrastructure projects are completed safely, efficiently, and to required standards.

What is the difference between Infrastructure Building vs Network Technician?

AspectInfrastructure BuildingNetwork Technician
Required CredentialsCertifications like Cisco CCNA, CompTIA Network+Certifications like Cisco CCNA, CompTIA Network+
Work EnvironmentDesigning, planning, and constructing network infrastructureInstalling, maintaining, and troubleshooting network hardware and software
Employer & Industry UsageTelecom, IT, construction companiesIT departments, service providers, corporate networks

While both roles involve networking skills and certifications, Infrastructure Building focuses on designing and constructing network systems, whereas Network Technicians primarily handle installation and maintenance. Understanding these differences helps clarify career paths and job expectations in the networking industry.

What are popular job titles related to Infrastructure Building jobs in Pennsylvania?

For Infrastructure Building jobs in Pennsylvania, the most frequently searched job titles are:

What job categories do people searching Infrastructure Building jobs in Pennsylvania look for?

The top searched job categories for Infrastructure Building jobs in Pennsylvania are:

What cities in Pennsylvania are hiring for Infrastructure Building jobs?

Cities in Pennsylvania with the most Infrastructure Building job openings:

Infrastructure Building jobs near you
Infographic showing various Infrastructure Building job openings in Pennsylvania as of June 2026, with employment types broken down into 81% Full Time, 17% Part Time, and 2% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution.

Senior Infrastructure Engineer

Cabaletta Bio Inc.

Philadelphia, PA

$109K - $148K/yr

Full-time

PTO

Re-posted 28 days ago

Job description

Position: Senior Infrastructure Engineer

 

Philadelphia, PA (Hybrid)

Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. The company recently presented final phase 1/2 data for rese-cel in myositis and expects to initiate the pivotal myositis trial this year. Cabaletta Bio's headquarters and labs are based in Philadelphia, PA. For more information, please visit www.cabalettabio.com and connect with us on LinkedIn.

At Cabaletta, we are driven by the shared mission of developing cures, where a patient's own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. And we're proud that for 3 years in a row, we've been nationally recognized by Great Place to Work and Fortune as one of the Top 10 Best Small/Medium Workplaces in Biopharma!

Senior Infrastructure Engineer Position Summary

The Senior Infrastructure Engineer is responsible for the administration, maintenance, security, and continuous improvement of Cabaletta Bio's infrastructure and cloud platforms. This role provides hands-on technical support for AWS, Windows and Linux server environments, networking, firewalls, cybersecurity controls, backup and disaster recovery capabilities, and emerging platform technologies.

The ideal candidate combines strong technical skills with excellent communication and customer service abilities, partnering effectively with scientific and business stakeholders, managed service providers, cloud partners, and internal IT resources within a regulated biotechnology environment. This position will help mature Cabaletta's infrastructure capabilities while supporting business growth, operational readiness, and future technology initiatives.

Essential Duties and Responsibilities Infrastructure Administration
  • Administer and support AWS cloud infrastructure, including EC2, VPCs, security groups, storage services, monitoring, and related cloud resources.
  • Administer, maintain, and troubleshoot Windows Server and Linux server environments.
  • Monitor infrastructure performance, availability, capacity, and reliability, and participate in planning, upgrades, patching, lifecycle management, and continuous improvement initiatives.
  • Maintain infrastructure documentation, architecture diagrams, technical standards, and operating procedures, and assist with development and implementation of operational processes and technical best practices.
Network and Connectivity
  • Support, maintain, and troubleshoot network infrastructure, including firewalls, VPN connectivity, routing, DNS, DHCP, and wireless networking services, across cloud, server, and application environments.
  • Assist with network design reviews and infrastructure improvements, and collaborate with managed service providers and infrastructure vendors to resolve complex technical issues.
Cloud and Platform Services
  • Design and support cloud-native and containerized workloads utilizing technologies such as Docker, ECS, EKS, and related platforms.
  • Assist with application hosting, platform administration, and infrastructure services supporting internal business systems and scientific computing workloads, and participate in cloud modernization, infrastructure automation, and platform engineering initiatives.
  • Support infrastructure requirements for data platforms, internal applications, and future AI-enabled solutions.
Cybersecurity and Risk Management
  • Implement and maintain infrastructure security controls and cybersecurity best practices.
  • Support vulnerability remediation, system hardening, patch management, access controls, and security monitoring activities.
  • Review infrastructure security recommendations and assist with implementation of corrective actions, collaborating with internal and external security resources to address identified risks.
  • Support security audits, assessments, and compliance initiatives as required.
Business Continuity and Disaster Recovery
  • Support backup administration, recovery procedures, disaster recovery planning, and infrastructure resilience initiatives, including participation in DR exercises, testing activities, and business continuity planning.
  • Maintain documentation supporting recovery procedures and infrastructure continuity requirements.
Vendor and Service Coordination
  • Serve as a technical point of contact for managed service providers, cloud partners, and infrastructure vendors.
  • Coordinate technical activities, projects, escalations, and support requests across external partners, reviewing vendor and partner recommendations to provide technical input and implementation support.
Customer Service and Collaboration
  • Communicate effectively with business users, scientific teams, and technology partners, providing technical guidance and support during infrastructure-related incidents, projects, and technology initiatives.
  • Partner closely with the Senior IT Systems Administrator and broader IT team to support enterprise technology services.
Qualifications Required Qualifications
  • Bachelor's degree in Information Technology, Computer Science, Engineering, or a related field, or equivalent experience.
  • 5+ years of progressive infrastructure administration experience.
  • Experience supporting biotechnology, pharmaceutical, or life sciences organizations, including work within GxP-regulated environments and experience with computer system validation (CSV), change control processes, and compliance-driven operations.
  • Experience administering AWS cloud environments.
  • Strong experience administering Linux and Windows Server environments.
  • Experience supporting network infrastructure, firewalls, VPNs, DNS, and related technologies.
  • Foundational cybersecurity experience, including vulnerability remediation, system hardening, access management, and security best practices.
  • Experience supporting backup, recovery, and disaster recovery processes.
  • Strong troubleshooting, root cause analysis, and problem-solving skills.
  • Strong written and verbal communication skills with the ability to work effectively with both technical and non-technical stakeholders.
  • Ability to work independently while collaborating effectively with internal teams, vendors, and external partners.
Preferred Qualifications
  • Experience supporting scientific, laboratory, clinical, manufacturing, quality, or regulatory business functions, including validated applications and infrastructure platforms.
  • Experience with Docker, containerized workloads, ECS, EKS, or Kubernetes.
  • Experience with infrastructure automation and scripting using PowerShell, Bash, Python, or similar technologies.
  • Experience supporting hybrid cloud environments.
  • AWS, Microsoft, Linux, networking, or security certifications.
Physical Requirements
  • Ability to sit and work at a computer for extended periods of time.
  • Ability to occasionally lift and move technology equipment weighing up to 25 pounds.
  • Ability to travel occasionally between company locations, data centers, or vendor sites as needed.
Reporting Structure

Reports to the Director, Information Technology and Data Sciences.

Our name - Cabaletta - is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, where the second act is designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression.

For more information, please visit https://www.cabalettabio.com/join-our-crew

Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.

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