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Hpc Postdoc Jobs in Raleigh, NC (NOW HIRING)

Maintain and optimize computational pipelines and model training workflows in HPC environments. * Collaborate with the PI, postdoctoral fellows, and students to advance research objectives and ...

Maintain and optimize computational pipelines and model training workflows in HPC environments. * Collaborate with the PI, postdoctoral fellows, and students to advance research objectives and ...

Hpc Postdoc information

What is an HPC postdoc?

HPC Postdocs, or High Performance Computing Postdoctoral Researchers, are scientists who have completed their PhD and are conducting advanced research that leverages powerful computational systems to solve complex problems. They often work at universities, research institutes, or national laboratories, focusing on developing new algorithms, optimizing code for supercomputers, or applying computational methods to scientific challenges. HPC Postdocs collaborate with interdisciplinary teams and may also provide support or training in HPC techniques for other researchers. Their work is essential for pushing the boundaries of science in fields such as physics, climate modeling, computational biology, and engineering.

What skills and qualifications are needed to thrive as an HPC postdoc?

To thrive as an HPC Postdoc, you need advanced knowledge in computational science, parallel programming, and a relevant doctoral degree, often in fields like physics, computer science, or engineering. Expertise in programming languages (such as C/C++, Fortran, Python), experience with high-performance computing systems, and familiarity with tools like MPI, OpenMP, or GPU computing frameworks are typically required. Strong analytical thinking, problem-solving, and collaboration skills set outstanding candidates apart in research environments. These competencies are crucial for conducting cutting-edge research, optimizing complex simulations, and advancing scientific discovery using supercomputing resources.

What are common challenges faced by an HPC postdoc when optimizing scientific applications for supercomputing environments?

HPC Postdocs often encounter the challenge of adapting complex scientific codes to efficiently utilize advanced supercomputing architectures. This may involve addressing issues such as parallel scalability, memory bottlenecks, and compatibility with different hardware or software environments. Collaborating closely with domain scientists, software engineers, and IT staff is essential to troubleshoot performance issues and implement effective solutions. Staying up-to-date with emerging HPC technologies and optimization techniques is also crucial for success in this role.

What are popular job titles related to Hpc Postdoc jobs in Raleigh, NC?

For Hpc Postdoc jobs in Raleigh, NC, the most frequently searched job titles are:

What cities near Raleigh, NC are hiring for Hpc Postdoc jobs?

Cities near Raleigh, NC with the most Hpc Postdoc job openings:

Infographic showing various Hpc Postdoc job openings in Raleigh, NC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 80% In-person, and 20% Hybrid job distribution.

Associate in Research

Duke University

Durham, NC • On-site

Full-time

Re-posted 18 days ago


Duke University rating

6.7

Company rating: 6.7 out of 10

Based on 55 frontline employees who took The Breakroom Quiz

485th of 618 rated colleges and universities


Job description

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.
Be You
The Department of Biostatistics and Bioinformatics at Duke University School of Medicine is seeking an Associate in Research to join an interdisciplinary research group developing advanced machine learning and transformer-based models for large-scale biological data.
In this role, you will work closely with the Principal Investigator Dr. Wenpin Hou and her research team to develop computational models that analyze single-cell multi-omics and perturbation datasets. Your work will contribute to cutting-edge projects at the intersection of artificial intelligence, genomics, and biomedical discovery.
You will help design and implement machine learning models, maintain computational pipelines, and analyze complex biological datasets using high-performance computing environments. This position offers the opportunity to contribute directly to grant-funded research projects, scientific publications, and new computational tools for the biomedical research community.
Minimum Requirements
  • Master's degree in Computer Science, Statistics, Biostatistics, Bioinformatics, Computational Biology, or a related quantitative field.
  • Strong programming skills.
  • Experience with machine learning frameworks such as PyTorch or TensorFlow.
  • Experience working with large-scale datasets and computational workflows.

Preferred Qualifications
  • Experience with transformer models or foundation models.
  • Experience analyzing single-cell or other high-dimensional biological datasets.
  • Familiarity with GPU computing and high-performance computing (HPC) environments.

Other Requirements
  • Ability to work collaboratively with researchers across computational and biomedical disciplines.
  • Strong organizational and documentation skills to support reproducible research workflows.
  • This position is hybrid eligible. The employee must reside in a Duke University-approved state.

Be Bold
Key responsibilities include:
  • Develop and implement transformer-based and deep learning models for large-scale biological datasets.
  • Process, curate, and analyze single-cell and multi-omics datasets, including perturbation data.
  • Maintain and optimize computational pipelines and model training workflows in HPC environments.
  • Collaborate with the PI, postdoctoral fellows, and students to advance research objectives and project milestones.
  • Support reproducible research, including workflow documentation, manuscript preparation, and grant-related deliverables.

Choose Duke
The Department of Biostatistics and Bioinformatics at Duke University School of Medicine is a globally recognized leader in biostatistics, data science, and AI-driven biomedical research. Our faculty collaborate widely across Duke's medical and data science communities to develop innovative computational methods that advance precision medicine and biological discovery.
By joining our team, you will work on cutting-edge AI and genomics research, collaborate with a diverse group of scientists and trainees, and contribute to impactful projects that translate computational advances into real-world biomedical insights.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions:
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

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About Duke University

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Duke is regarded as one of America's leading research universities. Located in Durham, North Carolina, Duke is positioned in the heart of the Research Triangle, which is ranked annually as one of the best places in the country to work and live. Duke has more than 15,000 students who study and conduct research in its 10 undergraduate, graduate, and professional schools. With about 40,000 employees, Duke is the third largest private employer in North Carolina, and it now has international programs in more than 150 countries.

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Colleges, universities, and professional schools and hospitals

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10,000+ Employees

Headquarters location

Durham, NC, US