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Hpc Performance Engineer Jobs in Missouri (NOW HIRING)

$55K - $100K/yr

... Performance Computing (HPC), Java (Programming Language), Linux, Machine Learning (ML), Omics, Perl Programming, Probabilistic Modeling, Python (Programming Language), R Programming, Statistical ...

Data Center IT Manager

Kansas City, MO · On-site

$146K - $220K/yr

... of AI, high-performance computing (HPC), and hyperscale cloud services . Our data centers host ... center engineering . This is a highly collaborative, innovation-driven environment where best ...

Data Center IT Manager

Kansas City, MO · On-site

$146K - $220K/yr

... of AI, high-performance computing (HPC), and hyperscale cloud services . Our data centers host ... center engineering . This is a highly collaborative, innovation-driven environment where best ...

$97K - $145K/yr

Strong programming skills in languages relevant to biological data analysis (e.g., Python, R) and ... Experience with HPC-scale computing and optimization methods for experimental design, including ...

... data on an HPC system. * Directly assist individual students and clinical researchers in ... Assists System Manager in maintaining system performance, system security, hardware/software ...

... Engineering):* Lead the design, curation, and application of high-quality chemistry and ... Critically assess model performance and limitations, guiding appropriate interpretation and use in ...

Showing results 41-59

Hpc Performance Engineer information

What is an HPC performance engineer?

HPC Performance Engineers are specialists who focus on optimizing the performance of high-performance computing (HPC) systems and applications. They analyze system bottlenecks, tune software and hardware configurations, and work with researchers and developers to ensure applications run efficiently on supercomputers or large computing clusters. Their work is essential for maximizing computational resources and improving the speed and scalability of scientific, engineering, or data-intensive workloads.

What are the key skills and qualifications needed to thrive as an HPC performance engineer?

To thrive as an HPC Performance Engineer, you need a strong background in computer science or engineering, with expertise in parallel programming, high-performance computing architectures, and performance analysis. Familiarity with tools like MPI, OpenMP, profiling software (e.g., Intel VTune, GNU gprof), and experience with job schedulers and Linux systems are essential. Analytical thinking, problem-solving, and effective communication are crucial soft skills for identifying bottlenecks and collaborating with multidisciplinary teams. These skills are vital for optimizing computational workflows, maximizing resource utilization, and driving efficiency in complex HPC environments.

What are the typical challenges HPC performance engineers face when optimizing large-scale computational workloads?

HPC Performance Engineers often encounter challenges such as identifying bottlenecks in parallel code, managing resource contention, and optimizing data movement across distributed systems. They must balance maximizing throughput with minimizing latency, all while ensuring applications scale efficiently as cluster sizes grow. Collaboration with software developers, system administrators, and research teams is common to align application requirements with hardware capabilities and to implement effective performance improvements.

What is the difference between Hpc Performance Engineer vs Hpc System Administrator?

AspectHpc Performance EngineerHpc System Administrator
Primary FocusOptimizing HPC system performance and efficiencyManaging and maintaining HPC infrastructure
Skills & CertificationsPerformance tuning, parallel computing, Linux, scriptingSystem setup, network management, user support
Work EnvironmentResearch labs, data centers, high-performance computing facilitiesData centers, IT departments, research institutions
Common TasksPerformance analysis, bottleneck resolution, code optimizationSystem installation, user account management, hardware troubleshooting

The Hpc Performance Engineer focuses on enhancing system performance and efficiency, often working on optimization and tuning. In contrast, the Hpc System Administrator manages the day-to-day operation and maintenance of HPC systems. Both roles are essential in high-performance computing environments but serve different core functions.

What cities in Missouri are hiring for Hpc Performance Engineer jobs?

Cities in Missouri with the most Hpc Performance Engineer job openings:

Solutions Architect - Drug Discovery

California, MO • On-site

NVIDIA Gruppe
Computer and Electronic Product Manufacturing • 10K+ employees

$56.50 - $74.25/hr

Other

Posted 6 days ago


Nvidia rating

9.6

Company rating: 9.6 out of 10

Based on 18 frontline employees who took The Breakroom Quiz

6th of 247 rated software companies


Job description

NVIDIA is seeking a Senior Solutions Architect to help redefine drug discovery and biological research through GPU-accelerated AI. This role will focus on enabling pharmaceutical and techbio customers to train, optimize, and deploy large biological foundation models using NVIDIA’s accelerated computing platform, models and libraries. Our Solutions Architects are elite developers, scientists, and technical leaders who thrive at the intersection of science, AI, and customer engagement. As a trusted technical advisor, you will work with leading organizations across North America to accelerate AI/ML workflows in areas such as genomics, quantum chemistry, biomaterials science, and structural biology. You will help customers integrate accelerated libraries, scalable training frameworks, and high-performance computing techniques to improve training efficiency, reduce time to insight, and unlock new scientific capabilities.

What you will be doing:
  • Partner with business and account teams to understand customer goals, scientific workflows, technical needs, and platform adoption strategies.
  • Architect and optimize AI/ML pipelines for training large biological foundation models, with a focus on BioNeMo libraries and GPU-accelerated software that improve training efficiency.
  • Build proof-of-concept demonstrations that show how NVIDIA software and hardware accelerate scientific discovery.
  • Collaborate across NVIDIA with subject matter experts, engineering, product, and field teams to bring the right technical expertise to customer engagements and deliver high-impact solutions.
  • Document best practices and teach others through technical enablement, partner training, whitepapers, blogs, internal wiki articles, and hands‑on customer workshops.
  • Serve as a trusted technical advisor for integrating NVIDIA technologies into advanced biopharma and diagnostics applications.
What we need to see:
  • MS or PhD in Computational Biology, Computational Chemistry, Computational Physics, Chemical Engineering, Biophysics, Computer Science, or a related technical field (or equivalent experience).
  • 5+ years of experience in software development for deep learning, GPU acceleration, or scientific computing applications.
  • Hands‑on experience applying ML to at least one of these domains: genomics, quantum chemistry, biomaterials science, or structural biology.
  • Experience profiling and optimizing training workflows for large AI models, including performance tuning, distributed training, data pipelines, and GPU utilization.
  • Proficiency with Linux environments and experience working in HPC or accelerated computing environments, including Slurm and/or Kubernetes‑based clusters.
  • Excellent communication skills, especially for presenting highly technical material to scientists, engineers, executives, and customer stakeholders.
  • A passion for working with forward‑thinking customers, learning continuously, and staying at the forefront of AI for life sciences.
Ways to stand out from the crowd:
  • Background with BioNeMo, NeMo, or related NVIDIA frameworks for training large biological or scientific foundation models.
  • Experience with Parabricks, RAPIDS‑singlecell, ALCHEMI, cuEquivariance, cuEST, or related accelerated libraries.
  • Experience working with pharmaceutical or biotech companies
  • Demonstration of customer‑facing technical leadership, including architecture reviews, executive briefings, technical workshops, or deployments at lighthouse accounts.

NVIDIA is widely considered to be one of the technology world's most desirable employers. We have some of the most forward‑thinking and hardworking people in the world working for us. If you're creative and autonomous, we want to hear from you!

Your base salary will be determined based on your location, experience, and the pay of employees in similar positions. The base salary range is 152,000 USD - 241,500 USD for Level 3, and 184,000 USD - 287,500 USD for Level 4.

You will also be eligible for equity and benefits.

Applications for this job will be accepted at least until September 4, 2026.

This posting is for an existing vacancy.

NVIDIA uses AI tools in its recruiting processes.

NVIDIA is committed to fostering an inclusive work environment and proud to be an equal opportunity employer. As we highly value diversity in our current and future employees, we do not discriminate (including in our hiring and promotion practices) on the basis of race, religion, color, national origin, gender, gender expression, sexual orientation, age, marital status, veteran status, disability status or any other characteristic protected by law.

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About Nvidia

Sourced by ZipRecruiter

NVIDIA has been transforming computer graphics, PC gaming, and accelerated computing for more than 25 years. It's a unique legacy of innovation that's fueled by great technology--and amazing people. Today, we're tapping into the unlimited potential of AI to define the next era of computing. An era in which our GPU acts as the brains of computers, robots, and self-driving cars that can understand the world. Doing what's never been done before takes vision, innovation, and the world's best talent.

Industry

Computer and electronic product manufacturing

Company size

10,000+ Employees

Headquarters location

Santa Clara, CA, US