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Hla Lab Jobs in Boston, MA (NOW HIRING)

Blood Bank Medical Director

Boston, MA · On-site

$279K - $310K/yr

Candidates with expertise and interest in other areas of laboratory medicine such as HLA/histocompatibility, hematology/hematopathology, special coagulation or molecular pathology are encouraged to ...

Hla Lab information

See Boston, MA salary details

$10

$27

$49

How much do hla lab jobs pay per hour?

As of Aug 1, 2026, the average hourly pay for hla lab in Boston, MA is $27.43, according to ZipRecruiter salary data. Most workers in this role earn between $20.91 and $30.29 per hour, depending on experience, location, and employer.

How to become an HLA technologist?

To become an HLA technologist, one typically needs a bachelor's degree in medical laboratory science, biology, or a related field, along with specialized training in histocompatibility and HLA testing. Certification from a recognized organization, such as the American Society for Histocompatibility and Immunogenetics (ASHI), is often required or preferred. Practical experience in a clinical laboratory setting and knowledge of laboratory techniques and tools are also important for this role.

What are some common challenges faced by professionals working in an HLA laboratory, and how can they be managed?

Professionals in an HLA laboratory often face challenges such as managing high sample volumes, maintaining strict quality control standards, and interpreting complex results for organ transplantation compatibility. Staying updated with rapidly evolving testing technologies and methodologies is also essential. Effective communication with clinicians and transplant teams is crucial to ensure accurate and timely reporting of critical results. These challenges are typically managed through ongoing training, robust laboratory protocols, and teamwork within a multidisciplinary environment.

What is an HLA job?

An HLA job typically involves working in laboratories or research settings focused on Human Leukocyte Antigen (HLA) testing and analysis. These roles often require knowledge of immunology, laboratory techniques, and may involve tasks such as tissue typing, genetic testing, or assisting in transplant compatibility assessments.

What is an HLA lab?

An HLA (Human Leukocyte Antigen) lab is a specialized laboratory that performs testing related to tissue typing and compatibility, primarily for organ and bone marrow transplantation. These labs analyze genetic markers on white blood cells to determine compatibility between donors and recipients, helping reduce the risk of transplant rejection. HLA labs also play a crucial role in disease association studies and monitoring for post-transplant complications. The work requires precision, advanced molecular techniques, and strict adherence to regulatory standards.

What is the difference between Hla Lab vs Histocompatibility Technician?

AspectHla LabHistocompatibility Technician
CredentialsTypically requires certification in HLA typing or histocompatibilityRequires certification in histocompatibility or related fields
Work EnvironmentLaboratory setting focused on HLA typing and tissue compatibility testingLaboratory environment performing tissue typing, crossmatching, and compatibility testing
Industry UsageUsed mainly in transplant immunology, research, and clinical labsCommonly employed in transplant centers, hospitals, and research institutions

Hla Lab and Histocompatibility Technician roles both involve tissue typing and compatibility testing, often requiring similar certifications. While Hla Lab may focus more on HLA typing techniques, the Histocompatibility Technician typically performs a broader range of tissue compatibility tests. Both roles are essential in transplant procedures and are found in similar healthcare and research settings.

What is the highest paying lab technician job?

The highest paying lab technician roles are often specialized positions such as clinical laboratory managers or senior research technicians, with salaries increasing for those with advanced certifications, extensive experience, or expertise in high-demand areas like molecular diagnostics or pharmaceutical research. These roles typically require additional training, leadership skills, and familiarity with advanced laboratory equipment.

What is an HLA technologist?

An HLA technologist is a laboratory professional who specializes in performing and analyzing human leukocyte antigen (HLA) testing, which is used for tissue typing, transplant compatibility, and disease association studies. They typically work in clinical laboratories, using techniques such as PCR and serology, and may require certification in laboratory sciences. Their role involves precise testing, data interpretation, and adherence to safety and quality standards.

What are the key skills and qualifications needed to thrive as an HLA Laboratory Technologist, and why are they important?

To thrive as an HLA Laboratory Technologist, you need a solid background in immunology, molecular biology, and laboratory science, often supported by a relevant degree and ASCP certification. Familiarity with PCR, flow cytometry, serological testing, and specialized HLA typing software is typically required. Strong attention to detail, analytical thinking, and effective teamwork are essential soft skills in this role. These competencies ensure precise genetic matching, accurate results, and effective collaboration critical to patient care, especially in transplantation medicine.
Infographic showing various Hla Lab job openings in Boston, MA as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $57,054 per year, or $27.4 per hour.

HLA Technologist / Blood Bank Technologist

KA Recruiting Inc.

Needham, MA

Full-time

Re-posted 3 days ago


Job description

HLA Technologist – Day Shift 

Seeking a full time HLT Technologist in the Great Boston area, this is a great location 30 minutes outside of Boston 


Schedule: Tuesday–Saturday, DAY SHIFT
Every third Saturday off (swap a weekday for Saturday)


Join a leading lab team performing high-complexity HLA testing and providing critical support to hospitals, transfusion services, and donor programs. This role is ideal for an experienced HLA, molecular, or blood bank professional who thrives in an independent, quality-driven environment.

Key Responsibilities
  • Perform advanced molecular and immunologic testing, including:

    • DNA extraction, PCR, sequence-based typing, STR analysis

    • Probe hybridization/detection

    • Cytotoxic crossmatching

    • Luminex and/or ELISA antibody screening

  • Recognize testing irregularities, troubleshoot issues, and determine solutions.

  • Review, interpret, and finalize test results; prepare accurate reports and maintain complete documentation.

  • Communicate with hospital and transfusion service personnel regarding patient findings and test orders.

  • Support sample receipt, coordination, transport, and reagent management.

  • Perform daily equipment checks, routine maintenance, troubleshooting, and vendor communication.

  • Perform and review quality control activities.

  • Assist with validation, implementation of new methods, and training of new team members.

  • Maintain compliance with all SOPs, federal, state, and accrediting agency standards.

Qualifications
  • Bachelor’s degree in biological science or chemistry.

  • MLS / MT / CLS (or equivalent) certification required.

  • CHT(ABHI) or CHS(ABHI) preferred (or in progress).

  • Minimum 3 years of experience in HLA, molecular diagnostics, blood bank, or clinical lab testing.

  • Strong communication skills, critical-thinking ability, and high attention to detail.

  • Ability to work independently and meet productivity standards.

Why This Role?
  • Highly specialized HLA lab work

  • Independent environment with strong technical depth

  • Opportunity to support critical patient care and transplantation services

  • Stable daytime schedule with rotating Saturday flexibility