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Genomic Variant Analyst Jobs in Oregon (NOW HIRING)

OR

$126K - $166K/yr

The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant interpretation, clinical review, and ...

Genomic Variant Analyst information

What does a Genomic Variant Analyst do?

A Genomic Variant Analyst is a specialist who examines genetic data to identify and interpret variations within genomes, such as mutations or structural changes in DNA. Their work is crucial for understanding genetic contributions to diseases, guiding clinical decision-making, and advancing personalized medicine. They use bioinformatics tools and databases to analyze sequencing data, annotate variants, and assess their significance. Genomic Variant Analysts often collaborate with clinicians, researchers, and laboratory staff to ensure accurate and meaningful interpretation of genomic information.

What are the key skills and qualifications needed to thrive as a Genomic Variant Analyst, and why are they important?

To thrive as a Genomic Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genomics or computational biology. Experience with genomic data analysis tools (like GATK, VEP, or IGV), next-generation sequencing (NGS) platforms, and familiarity with databases such as ClinVar are essential. Attention to detail, problem-solving skills, and effective communication are important soft skills for interpreting results and collaborating with multidisciplinary teams. These capabilities ensure accurate variant identification, meaningful clinical interpretations, and successful integration of genomic data into research or healthcare.

What are some common challenges faced by Genomic Variant Analysts when interpreting complex genetic data, and how are they addressed?

Genomic Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large volumes of sequencing data, and staying updated with rapidly evolving databases and guidelines. To address these, analysts rely on established variant classification frameworks, utilize collaborative review with clinical teams, and leverage specialized bioinformatics tools. Continuous professional development and participation in case discussions help ensure accurate interpretations and effective collaboration with genetic counselors and physicians.

How to become a genome analyst?

To become a genomic variant analyst, typically a bachelor's degree in genetics, biology, bioinformatics, or a related field is required, often followed by specialized training or a master's degree. Skills in data analysis, programming languages like Python or R, and experience with genomic databases and tools are essential. Certifications in bioinformatics or genomics can enhance job prospects, and familiarity with laboratory techniques and sequencing technologies is beneficial.

What is the highest paying job in genetics?

In genetics, roles such as genetic counselors, clinical geneticists, and research directors tend to have the highest salaries, often exceeding $150,000 annually. Senior positions requiring advanced degrees, certifications, and extensive experience typically command the highest compensation in the field.

What does a variant analyst do?

A genomic variant analyst examines genetic data to identify and interpret variations in DNA sequences that may be linked to diseases or traits. They use bioinformatics tools, databases, and statistical methods to analyze sequencing data, often working with next-generation sequencing technologies and requiring attention to detail and knowledge of genetics. Their work supports research, diagnostics, and personalized medicine efforts.

What does a genomic analyst do?

A genomic analyst studies genetic data to identify variations and mutations that may impact health or disease. They analyze DNA sequences using bioinformatics tools, interpret results, and often work in research or clinical laboratories, requiring knowledge of genetics, programming, and data analysis. Their work supports diagnostics, personalized medicine, and genetic research.

What is the difference between Genomic Variant Analyst vs Bioinformatics Technician?

AspectGenomic Variant AnalystBioinformatics Technician
Required CredentialsBachelor's or Master's in Genetics, Bioinformatics, or related field; experience with genomic data analysisAssociate's or Bachelor's in Bioinformatics, Computer Science, or related field; basic scripting skills
Work EnvironmentLaboratories, research institutions, biotech companiesResearch labs, hospitals, biotech firms, computational environments
Employer & Industry UsageGenomics research, clinical labs, pharmaceutical companiesData processing, supporting genomic research, data management

The Genomic Variant Analyst focuses on interpreting genetic variations and analyzing sequencing data, often requiring advanced bioinformatics skills. In contrast, the Bioinformatics Technician typically handles data management, basic analysis, and supporting research activities. While both roles work within genomics and bioinformatics, the analyst role involves more complex data interpretation and analysis, whereas the technician provides essential support functions.

What are popular job titles related to Genomic Variant Analyst jobs in Oregon? For Genomic Variant Analyst jobs in Oregon, the most frequently searched job titles are:
What job categories do people searching Genomic Variant Analyst jobs in Oregon look for? The top searched job categories for Genomic Variant Analyst jobs in Oregon are:
What cities in Oregon are hiring for Genomic Variant Analyst jobs? Cities in Oregon with the most Genomic Variant Analyst job openings:
Senior Product Manager, Clinical Genomics

Senior Product Manager, Clinical Genomics

Natera

OR

$126K - $166K/yr

Other

Posted 3 days ago


Natera rating

7.6

Company rating: 7.6 out of 10

Based on 37 frontline employees who took The Breakroom Quiz

60th of 120 rated laboratories


Job description

Senior Product Manager, Clinical Genomics Engineering

Natera offers genetic risk assessment and diagnostic tests to patients through medical providers. The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant  interpretation, clinical review, and reporting. As Natera scales across Women's Health, Oncology, and Organ Health, delivering  cohesive, reliable, and compliant software experiences is foundational to clinical quality and commercial success.

Natera is seeking a Senior Product Manager to define and drive strategy for core components of the Results, Interpretation, and Reporting (RIR) platform. This role is responsible for shaping scalable, compliant, and cohesive clinical software systems that support complex genomics workflows across multiple business units. The Lead PM will operate as a platform-level owner, ensuring long-term architectural soundness, regulatory robustness, and measurable clinical and operational outcomes.

Initial Focus and Scope Evolution

The Senior Product Manager will lead cross-functional alignment across engineering, clinical, quality, and downstream systems to ensure RIR components operate as a cohesive, scalable platform. This role will identify systemic gaps, resolve cross-team tradeoffs, and drive architectural and workflow decisions that support long-term growth and regulatory compliance.

This role will initially own one or more RIR software components or initiatives, with responsibility for defining long-term strategy, aligning cross-component workflows, and ensuring scalable architecture across user-facing applications, data contracts, and backend services. The Lead PM will drive strategic investment decisions, establish standards for usability and reliability, and ensure systems meet evolving clinical, operational, and regulatory requirements.

As business needs evolve, this role will expand to influence and coordinate across multiple RIR components, driving cohesive workflow design, shared data standards, and platform-level scalability across Women's Health, Oncology, and Organ Health.

Primary Responsibilities
  • Define and drive multi-year product strategy and roadmap across one or more RIR components, ensuring alignment to clinical quality, regulatory requirements, and commercial scale objectives

  • Influence platform-level technical direction in partnership with engineering leadership 

  • Partner closely with software engineering, bioinformatics, clinical domain experts, quality, regulatory, and other product teams

  • Translate business, clinical, and operational needs into clear, actionable product requirements

  • Define and evolve end-to-end user workflows, including UI/UX requirements and supporting backend functionality

  • Drive cross-team alignment on shared data contracts and workflow standards

  • Mentor and raise the bar for product management within the RIR organization

  • Own measurable improvements in clinical workflow efficiency, reliability, and operational scalability

  • Establish prioritization frameworks that balance regulatory risk, clinical impact, technical scalability, and business outcomes across RIR investments.

  • Develop and track quantitative metrics related to usability, performance, reliability, and adoption

  • Lead delivery teams with clear strategic direction, ensuring requirements reflect long-term platform goals, validation readiness, and system interoperability.

  • Proactively identify systemic risks, architectural constraints, and workflow inefficiencies that may limit scale or regulatory robustness, and lead cross-functional initiatives to resolve them

  • Partner with Quality and Regulatory leadership to shape validation strategy, risk classification, traceability, and audit readiness for RIR software systems.

  • Create clear, data-driven written proposals and presentations to support stakeholder alignment and decision-making

  • Act as a subject matter expert for owned components, supporting design, testing, validation, rollout, and ongoing use

QualificationsRequired
  • Bachelor's degree in life sciences, engineering, computer science, statistics, or equivalent experience

  • 5+ years of experience in software product management, including ownership of complex, multi-team or platform-level initiatives

  • 5+ years experience working on production software in healthcare, clinical genomics, or other regulated lifesciences domains, with demonstrated impact on validation, compliance, and system scalability

  • Demonstrated experience influencing engineering architecture and long-term technical investment decisions

  • Proven ability to drive alignment across highly matrixed organizations without direct authority
    Track record of independently operating in ambiguous environments and establishing product direction

Preferred
  • Experience with clinical genomics and variant processing and interpretation workflows

  • Experience owning user-facing applications, tools, or operational software

  • Familiarity working with backend services, APIs, or data-driven systems

Knowledge, Skills, and Abilities
  • Ability to operate effectively at both tactical and strategic levels, connecting detailed execution to broader platform vision.

  • Strong analytical skills with attention to quality, reliability, and user outcomes

  • Leads technical design discussions and critically evaluates architectural tradeoffs to ensure scalability, reliability, and regulatory integrity

  • Proven ability to influence without authority and drive alignment across teams

  • Clear, concise written and verbal communication skills across technical and non-technical audiences

  • Ability to manage multiple initiatives in a fast-paced, regulated environment

  • Familiarity with Next Generation Sequencing concepts is beneficial


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