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Genome Mapping Jobs in Arizona (NOW HIRING)

Genome Mapping information

Is genome mapping a good career?

Genome mapping is a specialized field within genetics and bioinformatics that involves analyzing DNA sequences to understand genetic structures. It offers opportunities in research, healthcare, and biotechnology, often requiring skills in molecular biology, data analysis, and laboratory techniques. The career can be rewarding for those interested in scientific discovery and innovation, with job prospects growing as genomics advances.

What is genome mapping?

Genome mapping is the process of determining the locations of genes and genetic markers within the chromosomes of an organism. It helps scientists understand the structure and organization of the genome, which can be crucial for identifying genes associated with diseases, traits, and evolutionary history. Genome mapping is used in research, medicine, and agriculture to support genetic analysis and improve breeding or treatment strategies. The process involves various techniques, including sequencing, molecular markers, and computational analysis.

What are the key skills and qualifications needed to thrive as a genome mapping specialist?

To thrive as a Genome Mapping Specialist, you need a solid background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in biology or genomics. Familiarity with genomic sequencing technologies, laboratory information management systems (LIMS), and data analysis software like BLAST or Genome Browser is essential. Strong analytical thinking, attention to detail, and effective collaboration skills set top performers apart in this field. These skills are crucial for accurately mapping genetic sequences, interpreting complex data, and driving meaningful insights in genomic research.

How to become a genome mapping analyst?

To become a genome mapping analyst, typically a bachelor's degree in genetics, biology, bioinformatics, or a related field is required. Gaining experience with genome sequencing tools, data analysis software, and programming languages like Python or R is important, along with knowledge of molecular biology and genetics. Advanced roles may require a master's or Ph.D. and certifications in bioinformatics or related areas.

What is the difference between Genome Mapping vs Genetic Technician?

AspectGenome MappingGenetic Technician
Required CredentialsAdvanced degrees in genetics or genomics, specialized trainingAssociate's or Bachelor's degree in biology or genetics
Work EnvironmentResearch labs, biotech companies, academic institutionsLaboratories, hospitals, research facilities
Industry UsageGenomics research, personalized medicine, biotech developmentSample processing, data collection, assisting in genetic testing

Genome Mapping involves advanced research and analysis of entire genomes, often requiring specialized degrees and working in research-focused environments. Genetic Technicians support genetic testing and data collection, typically with less formal education, working in clinical or lab settings. Both roles are essential in genetics but differ in scope, credentials, and work environment.

What job involves genome mapping?

A genome mapping technician or scientist is responsible for analyzing and constructing detailed maps of an organism's genome using laboratory techniques and bioinformatics tools. These roles often require knowledge of genetics, molecular biology, and specialized software, and may involve working in research laboratories or biotech companies.

What are some common challenges faced by professionals in genome mapping, and how can they be addressed?

Professionals in genome mapping often encounter challenges such as managing vast amounts of genomic data, ensuring data accuracy, and keeping up with rapidly evolving sequencing technologies. Collaborating closely with bioinformaticians, geneticists, and IT specialists can help address data management and analysis hurdles. Staying current with industry advancements through workshops and professional networks is also important for overcoming technical challenges and maintaining best practices.

Postdoctoral Research Associate, Cellular and Molecular Medicine

University of Arizona

Tucson, AZ • On-site

Other

Re-posted 10 days ago


University Of Arizona rating

7.2

Company rating: 7.2 out of 10

Based on 67 frontline employees who took The Breakroom Quiz

383rd of 614 rated colleges and universities


Job description

The laboratory combines human endothelial cell culture andperturbation systems with genomic discovery tools to dissect how geneticvariation at CAD-associated loci operates through the vessel wall.

Activeresearch areas include:

  • eQTL and splicing QTL (sQTL) mapping in human aortic and microvascular endothelial cells under physiological flow conditions.
  • Single-cell RNA sequencing and chromatin accessibility profiling across genetically diverse donor populations.
  • Colocalization of endothelial molecular QTLs with GWAS signals for CAD, blood pressure, and related vascular traits.
  • Integration with population-scale biobanks including UK Biobank, MVP, and All of Us.
  • Functional characterization of candidate effector genes emerging from colocalization, including surface proteins and splicing regulators operating through the hemodynamic flow-regulated transcriptional program.

Primary Job Duties Include:

  • Design and execute experiments using primary human endothelial cells hemodynamicshear stress conditions.
  • Prepare and QC sequencing libraries including bulk RNA-seq, small RNA-seq, ATAC-seq, and single-cell libraries.
  • Perform genome-scale quantiative trait locus (QTL) mapping analyses and genetic colocalization with genome wide association study (GWAS) summary statistics.
  • Analyze single-cell and bulk genomics datasets using standard and custom bioinformatics pipelines.
  • Contribute to grant writing, manuscript preparation, and presentations at national conferences.
  • Mentor and support graduate students and other members of the laboratory.

Knowledge, Skills & Abilities:

  • Ability operating shear stress devices (cone-and-plate and parallel-plate systems) in a laboratory setting.
  • Proficiency in sequencing library preparation, including bulk RNA-seq, small RNA-seq, ATAC-seq, and single-cell sequencing protocols (10x Genomics and sci-RNA-seq3).
  • Knowledge of genetic colocalization methods using GWAS and molecular QTL summary statistics.
  • Working knowledge of large-scale biobank resources, particularly the All of Us Research Program and phenome-wide association study (PheWAS) frameworks.   
  • Biological knowledge of vascular cell types, endothelial function, and the pathobiology of atherosclerosis. 

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