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Functional Genomics Jobs in Illinois (NOW HIRING)

Nait

Research Associate I

Campus, IL · On-site

Lead bioinformatic analysis of microbial genomic and metagenomic datasets, including sequence assembly, genome reconstruction, annotation, comparative genomics, phylogenetic analysis, and functional ...

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All JobsFunctional Genomics JobsFunctional Genomics Jobs in Illinois

Functional Genomics information

See Illinois salary details

$43.6K

$79.7K

$125.5K

How much do functional genomics jobs pay per year?

As of Sep 7, 2026, the average yearly pay for functional genomics in Illinois is $79,737.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,100.00 and $91,100.00 per year, depending on experience, location, and employer.

What is functional genomics?

A Functional Genomics job involves studying how genes and their interactions influence biological functions, often using high-throughput technologies like RNA sequencing and CRISPR screening. Professionals in this field analyze large genomic datasets to understand gene expression, regulation, and their role in health and disease. They work in academia, biotechnology, or pharmaceutical industries, contributing to drug discovery, personalized medicine, and agricultural advancements. This role requires expertise in molecular biology, bioinformatics, and computational analysis to interpret complex genomic data.

What does a functional genomics specialist do?

Professionals in functional genomics typically spend their days designing and conducting experiments to investigate gene function, analyzing large genomic datasets using bioinformatics tools, and interpreting results to advance biological understanding. Their work often involves both hands-on laboratory work and computational analysis, requiring close collaboration with research scientists, lab technicians, and data analysts. You may also participate in team meetings to discuss findings, contribute to scientific publications, and stay updated on the latest technologies in the field. This dynamic environment ensures that no two days are exactly alike and provides ongoing opportunities to develop both scientific expertise and technical skills.

What skills and qualifications are needed for functional genomics?

To excel in functional genomics, a strong background in molecular biology, genetics, bioinformatics, and often a relevant advanced degree (such as a Ph.D. or M.S.) is required. Expertise in using high-throughput sequencing technologies, data analysis platforms like R/BioConductor, and familiarity with laboratory automation tools are highly valued. Excellent problem-solving, critical thinking, teamwork, and communication skills set top candidates apart in this field. These capabilities are crucial for designing experiments, analyzing complex datasets, and collaborating effectively on multidisciplinary research projects.

Does functional genomics pay well?

Functional genomics professionals typically earn competitive salaries that vary based on experience, education, and location. Entry-level positions may start around $50,000 to $70,000 annually, while experienced researchers or specialists can earn over $100,000. Skills in bioinformatics, laboratory techniques, and data analysis can influence earning potential.

What jobs can you get with a functional genomics degree?

A degree in functional genomics can lead to roles such as research scientist, bioinformatics analyst, laboratory technician, or molecular biologist. These positions often require skills in data analysis, laboratory techniques, and familiarity with genomic tools and software.

What are popular job titles related to Functional Genomics jobs in Illinois?

For Functional Genomics jobs in Illinois, the most frequently searched job titles are:

What job categories do people searching Functional Genomics jobs in Illinois look for?

The top searched job categories for Functional Genomics jobs in Illinois are:

Functional Genomics jobs near you
Infographic showing various Functional Genomics job openings in Illinois as of August 2026, with employment types broken down into 92% Full Time, and 8% Contract. Highlights an 100% In-person job distribution, with an average salary of $79,737 per year, or $38.3 per hour.

Senior Director, Functional Genomics & Organoid Systems Biology

Tempus

Chicago, IL • On-site

Full-time

PTO

Re-posted 17 days ago

Job description

Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are seeking an exceptional Senior Director, Functional Genomics & Organoid Systems Biology to lead and expand our patient-derived organoid (PDO) biology platform. This leader will drive the wet lab component of our systems biology team, and will help define how this experimental layer will combine with computational approaches and the massive multimodal Tempus data layer to unlock new biological insights. This leader will oversee a multidisciplinary team of scientists and research associates responsible for executing large-scale functional screens-including CRISPR-based genetic perturbation screens, drug sensitivity screens, single-cell and spatial technologies, and combination therapy studies-in clinically annotated patient-derived organoid models.
The successful candidate will define and drive the scientific vision for leveraging PDOs to validate hypotheses generated from Tempus' unique real-world clinico-genomic data assets. Working closely with computational scientists, machine learning researchers, translational scientists, and clinical teams, this individual will establish an integrated discovery engine that translates patient data into experimentally validated therapeutic opportunities.
This is a highly visible leadership role that combines scientific strategy, organizational leadership, platform development, and translational research to identify novel targets, biomarkers, and therapeutic strategies for cancer patients.
This position is based in Tempus' Chicago lab: hybrid or remote candidates will not be considered.
Key Responsibilities
  • Define and execute the long-term scientific strategy for functional screening and target discovery using patient-derived organoid models.
  • Establish a world-class organoid-based discovery platform capable of validating hypotheses generated from large-scale multimodal patient datasets.
  • Serve as a scientific thought leader internally and externally, representing the company through publications, presentations, and strategic collaborations.
  • Oversee the design, execution, and interpretation of large-scale CRISPR screening campaigns, including knockout, activation, interference, and pooled screening approaches.
  • Lead drug screening efforts across diverse PDO models to identify therapeutic sensitivities, resistance mechanisms, and rational drug combinations.
  • Drive development of next-generation functional assays incorporating co-culture systems, immune components, and emerging technologies.
  • Establish rigorous experimental standards, quality systems, and reproducible workflows across the screening platform.
  • Ensure efficient scaling of laboratory operations to support discovery and translational research objectives.
  • Partner closely with computational biology and data science teams to prioritize hypotheses arising from real-world patient data.
  • Create an iterative discovery framework in which computational predictions are experimentally tested and experimental findings inform subsequent computational analyses.
  • Collaborate with clinical, molecular profiling, and translational research teams to connect experimental findings with patient outcomes and therapeutic hypotheses.
  • Build, lead, and mentor a high-performing team of scientists, research associates, and laboratory personnel.
  • Foster a culture of scientific excellence, innovation, accountability, and collaboration.
  • Recruit top-tier talent across functional genomics, organoid biology, and translational oncology.
  • Establish clear goals, development plans, and performance expectations for team members.
  • Manage departmental budgets, resource allocation, and strategic planning.

Required Qualifications
  • PhD, MD, or MD/PhD in Cancer Biology, Molecular Biology, Genetics, Functional Genomics, Bioengineering, or a related discipline.
  • 8+ years of relevant industry and/or academic experience, including substantial leadership experience.
  • Deep expertise in cancer biology, functional genomics, and target discovery.
  • Demonstrated experience leading CRISPR-based screening programs and large-scale functional biology initiatives.
  • Hands-on experience with patient-derived organoids, ex vivo models, or other clinically relevant disease model systems.
  • Track record of translating biological insights into therapeutic hypotheses, biomarkers, or drug discovery programs.
  • Experience managing and mentoring multidisciplinary scientific teams.
  • Strong publication and/or patent record demonstrating scientific impact.
  • Excellent communication skills and ability to influence across scientific and executive stakeholders.

CHI: $190,000 - $270,000
The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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