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Cambridge, US; Gaithersburg, US; New Jersey, US   |   full time   |   Job ID: 11654 

About the Role:

At BioNTech, we are committed to revolutionizing medicine through cutting-edge science and innovation. As Associate Director, Clinical Pharmacology & Pharmacometrics, you will play a pivotal role in advancing our drug development pipeline. With limited supervision, you will lead the design and execution of clinical pharmacology studies, provide scientific expertise in pharmacokinetics (PK), pharmacodynamics (PD), and pharmacometrics (PMx), and contribute to regulatory submissions such as INDs and NDA/BLAs. Collaborating with multidisciplinary teams, you'll drive strategies that shape the future of transformative therapies for oncology, infectious diseases, and beyond.

This is an opportunity to make a meaningful impact on patient lives while mentoring the next generation of scientists in a dynamic and innovative environment.

Your Contribution:

• Lead the analysis, interpretation, and reporting of clinical pharmacokinetic data
• Drive PKPD modeling, exposure-response analyses, and translational quantitative pharmacology activities to support optimal dose and dose selection decisions 
• Plan, design, execute, and report clinical pharmacology studies (e.g., QT assessments, food effect studies, ADME investigations, DDI strategies) to support drug development and rapid product registration by working with cross-functional teams
• Collaborate with research leads on study design and data interpretation of PK, toxicokinetic and PD aspects of preclinical studies
• Provide clinical pharmacology and pharmacometrics input into regulatory documents (e.g., IBs, briefing books, NDA/BLA submissions)
• Represent BioNTech at global health authority meetings, providing clinical pharmacology and pharmacometrics expertise

A Good Match:

• Advanced scientific training (Ph.D., MD, or Pharm.D.) in pharmaceutics, pharmacokinetics, pharmacology, pharmacometrics or related discipline
• Minimum 5 years of experience in clinical pharmacology within the biotechnology or pharmaceutical industry
• Proven track record leading drug development programs from early exploratory studies through Phase 2/3 trials
• Expertise in translational research or pharmacometrics applied to oncology or infectious disease drug development
• Proficiency with modeling software such as Phoenix WinNonlin, R, NONMEM, MATLAB
• Strong communication and presentation skills with ability to lead cross-functional teams in a matrix environment
• Self-motivated with a collaborative mindset and commitment to innovation

Join us at BioNTech where your expertise will contribute directly to improving patient outcomes worldwide. Together we can shape the future of medicine.

Your benefits and remuneration:

Expected Pay Range: $146,300/year to $234,100/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
• 401(K) Plan with Company Match
• Tuition Reimbursement & Student Loan Assistance Programs
• Wellbeing Incentive Platforms & Incentives
• Professional Development Programs
• Commuting Allowance and subsidized parking
• Discounted Home, Auto & Pet Insurance

...and more! More details to be shared.
 

Home to dozens of research institutions, biopharmaceutical companies, life science incubators, venture capital firms, and over 30 million square feet of laboratory space, Cambridge, Massachusetts has earned a reputation as the #1 life science cluster in the world. As part of the Greater Boston area, the city is often referred to as the "biotech supercluster" due to its high concentration of life sciences firms. This unique ecosystem is the result of a model partnership between academia and industry, fostering collaboration and innovation and driving the development of new therapies, medical devices, and diagnostics. As Cambridge's thriving life sciences industry continues to evolve, the city remains a beacon of knowledge, innovation, and collaboration, poised to shape the future of science and technology.

Apply now - We look forward to your application!

Apply for our Cambridge, US; Gaithersburg, US; New Jersey, US location and simply send us your documents using our online form.

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider 'HireRight'. You will be informed accordingly by your BioNTech-Recruiter.