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Fluorescent In Situ Hybridization Jobs (NOW HIRING)

Provide interpretation of in-situ hybridization (ISH) stains. * Review batch and instrument quality control stains as needed. * Evaluate pathology specimens and render insightful and comprehensive ...

Process and prepare fixed and unfixed tissue and cytology specimens using histologic, frozen sectioning, immunohistochemical, in situ hybridization, and tissue microarray techniques. * Competitive ...

Cytogenetic Technologist

Rosemont, IL · On-site

$35.50 - $53.25/hr

Proficiently and independently performs chromosome analysis, Fluorescent in situ Hybridization (FISH) analysis, and Microarray analysis in accordance with the department's procedure manual and proper ...

Provide interpretation of in-situ hybridization (ISH) stains. * Review batch and instrument quality control stains as needed. * Evaluate pathology specimens and render insightful and comprehensive ...

Basic understanding of molecular biology, immunology, immunohistochemistry, flow cytometry, fluorescent in situ hybridization * Familiarity with statistical analysis * Strong communication ...

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Fluorescent In Situ Hybridization information

What are the key skills and qualifications needed to thrive as a Fluorescent In Situ Hybridization (FISH) technologist, and why are they important?

To thrive as a Fluorescent In Situ Hybridization (FISH) technologist, you need a background in molecular biology, cytogenetics, or a related life sciences field, often supported by a bachelor's degree or higher. Familiarity with laboratory information systems, fluorescence microscopy, and FISH-specific software, along with certifications like CG(ASCP), is highly valuable. Attention to detail, strong analytical thinking, and effective communication skills help ensure accurate analysis and reporting of results. These competencies are critical for producing reliable genetic data that inform patient diagnoses and treatment decisions.

What is the difference between Fluorescent In Situ Hybridization vs Cytogenetic Technologist?

AspectFluorescent In Situ HybridizationCytogenetic Technologist
CredentialsTypically requires a biology or medical laboratory science degree, often with specialized training in FISH techniquesRequires a cytogenetics certification or a related degree in genetics or molecular biology
Work EnvironmentLaboratory settings focusing on molecular and genetic analysis using fluorescence microscopyClinical labs performing chromosome analysis and karyotyping
Industry UsageUsed in genetic testing, cancer diagnostics, and researchPrimarily employed in clinical genetics and cytogenetics laboratories

While both roles involve genetic analysis, Fluorescent In Situ Hybridization specializes in detecting specific DNA sequences using fluorescence, whereas Cytogenetic Technologists focus on analyzing chromosomes and karyotypes. Both require specialized training and are vital in genetic diagnostics, but they differ in techniques and focus areas.

What is Fluorescent In Situ Hybridization (FISH)?

Fluorescent In Situ Hybridization (FISH) is a laboratory technique used to detect and localize specific DNA or RNA sequences in cells or tissue sections using fluorescent probes. This method allows researchers and clinicians to visualize genetic abnormalities, such as chromosomal rearrangements, duplications, or deletions, directly on the chromosomes or within tissues. FISH is widely used in genetic research, cancer diagnosis, and prenatal screening because of its high sensitivity and ability to provide spatial information about genetic material within cells.

What are some common challenges faced by Fluorescent In Situ Hybridization (FISH) technologists, and how can they be addressed?

FISH technologists often encounter challenges such as ensuring probe specificity, minimizing background fluorescence, and interpreting complex or borderline results. Working in a laboratory setting, technologists must maintain strict adherence to protocols, troubleshoot technical issues, and collaborate closely with pathologists and other laboratory staff to ensure accurate diagnoses. Continuous training, participation in quality assurance programs, and staying updated with advancements in FISH methodologies can help overcome these challenges and enhance both efficiency and accuracy in the role.

Oncologic Pathologist

Caris Life Sciences

Phoenix, AZ • On-site

Full-time

Posted 10 days ago


Job description

At Caris, we understand that cancer is an ugly word-a word no one wants to hear, but one that connects us all. That's why we're not just transforming cancer care-we're changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day:"What would I do if this patient were my mom?"That question drives everything we do.

But our mission doesn't stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare-driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

The Pathologist, with expertise in Oncology and/or Molecular Pathology, will analyze and understand the laboratory and clinical aspect of high complexity tests, as offered by Caris Life Sciences, to provide up to date clinically relevant pathological diagnoses, interpret immunohistochemical and in situ hybridization tests, select areas of tumor for molecular analyses, and explain the clinical and pathological significance of his/her interpretations.

Job Responsibilities

  • Conduct pathologic examination of submitted specimens.

  • Evaluate adequacy of specimens for testing and make recommendations when limited specimen is available.

  • Provide interpretation of immunohistochemical (IHC) stains.

  • Provide interpretation of in-situ hybridization (ISH) stains.

  • Review batch and instrument quality control stains as needed.

  • Evaluate pathology specimens and render insightful and comprehensive diagnoses to enable clinicians to best treat their patients.

  • Review all elements of a tumor profiling and sign-out the report.

  • Consult with peer Pathologists on cases as requested or needed.

  • Participate in Quality Assurance programs, i.e., serve as reviewer for cases and participate in intradepartmental conferences to ensure and improve accuracy of diagnoses and quality of care.

  • May train and supervise pathology assistants, residents and fellows engaged in specialty training.

  • Follow established policies, procedures, and objectives, continuous quality improvement objectives, safety, environmental, and/or control standards.

  • Promote and work to improve relationships with clinicians and the pathology community.

  • Assist with projects from Pharma Services.

  • Assist as needed to perform other related duties and special projects as required.

Required Qualifications

  • The Pathologist must be a M.D. or D.O. with AP or AP/CP Board certification (if candidate has more than 2 yrs. of experience) or Board eligibility.

  • Eligibility for licensure in Arizona and other states to satisfy needs of the national referral laboratory providing services across the USA.

  • Ability to provide the highest level of tumor profiling support for cancer patients and advancement of science of oncology.

  • Ability to learn internal software programs for diagnosis purposes.

  • Knowledge and experience using diagnostic equipment (microscope, computer).

  • Ability to communicate effectively.

  • Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.

Preferred Qualifications

  • Additional subspecialty fellowship training (with Board eligibility or certification) in Molecular Pathology and/or other surgical pathology subspecialties is preferred but not required.

  • Additional advantage will be given to applicants with publications using immunohistochemistry, in-situ hybridization, or molecular genetic testing methods particularly in cancer investigations.

Training

  • All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

  • This is a full-time on-site position in Phoenix, AZ.

  • One weekend day per week required.

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check( applicable for certain positions) and reference verification.

This job description reflects management's assignment of essential functions. Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.