Postdoctoral Associate
Job no: 536740
Work type: Research Faculty
Senior management: Vice President for Research
Department: Fralin Biomedical Res. Institute
Location: Roanoke, Virginia
Categories: Research / Scientific
Job Description
The Fralin Biomedical Research Institute at VTC in Roanoke, VA, is dedicated to the promotion of health and the prevention and treatment of lifestyle-related disease. The Mishra Laboratory at FBRI is seeking a highly motivated Postdoctoral Associate to work on AHA-funded research projects focused on cardiometabolic disease, heart failure with preserved ejection fraction (HFpEF), mitochondrial biology, cardiac remodeling, and cardiovascular physiology.
The primary responsibilities of this position include designing and conducting independent research studies using in vitro and in vivo models, analyzing and interpreting experimental data, preparing manuscripts and grant applications, and mentoring trainees within the laboratory. A major component of this position will involve mouse cardiovascular physiology and cardiac disease modeling, including small-animal cardiac surgery models such as transverse aortic constriction (TAC), myocardial infarction (MI), and related models of cardiac stress, remodeling, and heart failure. The successful candidate will also participate in mouse echocardiography, exercise interventions, tissue collection, molecular biology, biochemical analyses, and animal colony management. The candidate should be detail-oriented, self-motivated, and able to work both independently and collaboratively in a fast-paced research environment.
Required Qualifications
• PhD in Cardiovascular Physiology, Molecular Biology, Biochemistry, Exercise Physiology, Biology, Veterinary Sciences, or a related field. PhD must be awarded no more than four years prior to the effective date of appointment, with a minimum of one year eligibility remaining.
• Experience with mouse handling, animal experimentation, and in vivo cardiovascular research models.
• Hands-on experience or strong working knowledge of small-animal cardiac surgery models, including TAC, MI, or related models of cardiac injury, remodeling, or heart failure.
• Experience in molecular biology techniques including RT-PCR, western blotting, cloning, immunostaining, fluorescence microscopy, mammalian cell culture, and biochemical assays.
• Strong scientific writing skills with a demonstrated record of publications and presentations.
• Ability to work independently and manage multiple projects.
• Ability to stand, walk, stoop, bend for long periods of time.
Preferred Qualifications
• Demonstrated experience performing mouse cardiac surgeries, especially TAC, MI, ischemia-reperfusion injury, or related cardiovascular disease models.
• Experience with mouse echocardiography and in vivo cardiovascular phenotyping.
• Experience with cardiovascular physiology, heart failure, cardiac remodeling, or cardiometabolic disease research.
• Experience with metabolism, mitochondrial biology, or molecular mechanisms of cardiac dysfunction.
• Experience with exercise physiology and/or HFpEF research.
• Prior mentoring or teaching experience.
Overtime Status
Exempt: Not eligible for overtime
Appointment Type
Restricted
Salary Information
63,480-70,000
Hours per week
40+
Review Date
7/6/26
Additional Information
The successful candidate will be required to have a criminal conviction check.
About Virginia Tech
Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicine college, Graduate School, and Honors College. The university has a significant presence across Virginia, including Blacksburg, the greater Washington, D.C. area, the Health Sciences and Technology Campus in Roanoke, sites in Newport News and Richmond, and numerous Extension offices and research institutes. A leading global research institution, Virginia Tech conducts more than $650 million in research annually.
Virginia Tech endorses and encourages participation in professional development opportunities and university shared governance. These valuable contributions to university shared governance provide important representation and perspective, along with opportunities for unique and impactful professional development.
Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, ethnicity or national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law.
If you are an individual with a disability and desire an accommodation, please contact Brittany Shelton at sheltb@vtc.vt.edu during regular business hours at least 10 business days prior to the event.
Advertised: June 23, 2026
Applications close:
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