Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Scientist, Solid Tumor CAR-T
Philadelphia, PA ยท On-site
$110K - $145K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Scientist, Solid Tumor CAR-T
Philadelphia, PA ยท On-site
$110K - $145K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Scientist, Solid Tumor CAR-T
Philadelphia, PA ยท On-site
$110K - $145K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Scientist, Solid Tumor CAR-T
Philadelphia, PA ยท On-site
$110K - $145K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. Role Overview We are seeking a highly motivated Scientist to join our ...
Scientist, In Vivo CAR-T Pipeline
Philadelphia, PA ยท On-site
$96K - $126K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Legend Biotech is seeking a Scientist, In Vivo CAR-T Pipeline as part of the Research and Development team based in Philadelphia, PA . Role Overview Legend Biotech is a global leader in the ...
Scientist, In Vivo CAR-T Pipeline
Philadelphia, PA ยท On-site
$96K - $126K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Legend Biotech is seeking a Scientist, In Vivo CAR-T Pipeline as part of the Research and Development team based in Philadelphia, PA . Role Overview Legend Biotech is a global leader in the ...
Senior Data Scientist, CAR-T & Immunology Analytics (Cambridge)
Cambridge, MA ยท On-site
$130K - $170K/yr
... CAR immunology programs while collaborating with experimental scientists to translate data into actionable biological insights. The ideal candidate will have a Ph.D. and experience with CAR-T or RNA ...
Senior Data Scientist, CAR-T & Immunology Analytics (Cambridge)
Cambridge, MA ยท On-site
$130K - $170K/yr
... CAR immunology programs while collaborating with experimental scientists to translate data into actionable biological insights. The ideal candidate will have a Ph.D. and experience with CAR-T or RNA ...
Senior Scientist/Principle Scientist- Cell Biology and Immunology
Piscataway, NJ ยท On-site
$91K - $125K/yr
While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular ... Supervise associate scientists for routine laboratory work * Help group leader for general ...
Senior Scientist/Principle Scientist- Cell Biology and Immunology
Piscataway, NJ ยท On-site
$91K - $125K/yr
While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular ... Supervise associate scientists for routine laboratory work * Help group leader for general ...
While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular ... Supervise associate scientists for routine laboratory work * Help group leader for general ...
While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular ... Supervise associate scientists for routine laboratory work * Help group leader for general ...
Design and lead projects focused on understanding and augmenting CAR T cell function in specific ... The Staff Scientist must possess, at a minimum, a Ph.D. or other doctoral level degree, or ...
Design and lead projects focused on understanding and augmenting CAR T cell function in specific ... The Staff Scientist must possess, at a minimum, a Ph.D. or other doctoral level degree, or ...
... CAR T cell function in specific microenvironmental contexts, using canonical immune signaling and ... Your qualifications should include: ยท The Staff Scientist must possess, at a minimum, a Ph.D. or ...
... CAR T cell function in specific microenvironmental contexts, using canonical immune signaling and ... Your qualifications should include: ยท The Staff Scientist must possess, at a minimum, a Ph.D. or ...
The lab focuses on developing next-generation CAR-T cell therapies for autoimmune diseases ... The Staff Scientist will contribute to experimental design, execution, troubleshooting, and ...
The lab focuses on developing next-generation CAR-T cell therapies for autoimmune diseases ... The Staff Scientist will contribute to experimental design, execution, troubleshooting, and ...
The lab focuses on developing next-generation CAR-T cell therapies for autoimmune diseases ... The Staff Scientist will contribute to experimental design, execution, troubleshooting, and ...
The lab focuses on developing next-generation CAR-T cell therapies for autoimmune diseases ... The Staff Scientist will contribute to experimental design, execution, troubleshooting, and ...
The lab focuses on developing next-generation CAR-T cell therapies for autoimmune diseases ... The Staff Scientist will contribute to experimental design, execution, troubleshooting, and ...
The lab focuses on developing next-generation CAR-T cell therapies for autoimmune diseases ... The Staff Scientist will contribute to experimental design, execution, troubleshooting, and ...
Experienced Scientist, In-vivo CAR-T
Spring House, PA ยท On-site
$110 - $140/hr
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose The Experienced Scientist will support the ...
New
Experienced Scientist, In-vivo CAR-T
Spring House, PA ยท On-site
$110 - $140/hr
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose The Experienced Scientist will support the ...
New
Entry Level Car Detailer - Post Production
Hutchins, TX ยท On-site
$17 - $18/hr
Medical
Retirement
PTO
We're hiring for entry-level automotive roles at Carvana - the fastest-growing used automotive ... Our promise is simple: we won't sell a car to a customer that we wouldn't sell to our own Mom.
Entry Level Car Detailer - Post Production
Hutchins, TX ยท On-site
$17 - $18/hr
Medical
Retirement
PTO
We're hiring for entry-level automotive roles at Carvana - the fastest-growing used automotive ... Our promise is simple: we won't sell a car to a customer that we wouldn't sell to our own Mom.
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose: The Experienced Scientist will support the ...
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose: The Experienced Scientist will support the ...
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose: The Experienced Scientist will support the ...
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose: The Experienced Scientist will support the ...
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose: The Experienced Scientist will support the ...
We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. Purpose: The Experienced Scientist will support the ...
Scientist
Philadelphia, PA ยท Hybrid
The successful candidate will contribute to the development of our in vivo CAR-T platform and ... This role requires scientific excellence, strong collaboration skills, and the ability to drive ...
Scientist
Philadelphia, PA ยท Hybrid
The successful candidate will contribute to the development of our in vivo CAR-T platform and ... This role requires scientific excellence, strong collaboration skills, and the ability to drive ...
Scientist, II
South San Francisco, CA ยท On-site
$84K/yr
Medical
Dental
Vision
Retirement
PTO
AbbVie's CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist II to support the development of in vivo CAR-T platforms from concept through ...
Scientist, II
South San Francisco, CA ยท On-site
$84K/yr
Medical
Dental
Vision
Retirement
PTO
AbbVie's CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist II to support the development of in vivo CAR-T platforms from concept through ...
Entry Level Car T Scientist information
See salary details
$50.5K - $58.4K
2% of jobs
$58.4K - $66.3K
0% of jobs
$66.3K - $74.2K
5% of jobs
$74.2K - $82.1K
0% of jobs
$82.1K - $90K
1% of jobs
$93.1K is the 25th percentile. Wages below this are outliers.
$90K - $98K
42% of jobs
$98K - $105.9K
1% of jobs
$105.9K - $113.8K
1% of jobs
$113.8K - $121.7K
19% of jobs
$121.7K - $129.6K
0% of jobs
$130.4K is the 75th percentile. Wages above this are outliers.
$129.6K - $137.5K
28% of jobs
$50.5K
$111.3K
$137.5K
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Full-time
Posted 27 days ago
Job description
Legend Biotech is seeking a Scientist, Solid Tumor CAR-Tย as part of the Research and Development team based in Philadelphia, PA.ย
Role Overview
We are seeking a highly motivated Scientist to join our interdisciplinary cell therapy team at Legend Biotech, focused on advancing CAR-T cell therapies for solid tumors. This role is central to our in vivo CAR-T platform and will drive preclinical development from construct design through animal model efficacy studies.
The ideal candidate holds a PhD in Immunology, Immuno-Oncology, or a closely related discipline, with up to 3 years of postdoctoral experience. You are a rigorous scientist who thrives in a fast-paced, collaborative environment and is passionate about translating basic immunology insights into transformative oncology therapies.
Key Responsibilities
- Design and execute in vitro CAR-T functional assays.
- Perform comprehensive phenotypic analysis of T cell differentiation, activation, and memory subsets.
- Evaluate CAR-T cell trafficking and tumor infiltration in vivo using flow cytometry and immunohistochemistry.
- Handling and engineering human and murine T cells as well as various cancer cells.
- Engineering and maintaining various cancer cell lines for model development.
- Analyze and interpret data, troubleshooting, maintain detailed experimental records.ย
Requirements
- A scientist in Immunology, Immuno-Oncology, Tumor Immunology, Cancer Biology, or a closely related field.
- Candidates completing ther PhD within the past 3 years are strongly encouraged to apply.
- Primary human T cell isolation, activation, lentiviral transduction, and expansion is required.
- Multicolor flow cytometry: panel design, data acquisition (e.g., Attune,Novocyte, Cytek Aurora), and analysis (FlowJo).
- Standard molecular biology: PCR/qPCR, lentiviral vector packaging and titration, Western blot.
- Experience with humanized mouse models for in vivo CAR-T evaluation.
- Proficiency in CAR-T cell trafficking studies: IHC/IF of tumor sections, in vivo imaging.
- Familiarity with gene editing tools (CRISPR/Cas9) for cell engineering.
- Experience with in vitro Organoid cancer model establishment and expansion.
- Experience in solid tumor indications (e.g., lung, gastric, or other refractory cancers).
- Contributions to innovation in cell therapy (publications, patents, or conference presentations).
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