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The Associate Researcher I will support research projects focused on stem cell disease modeling, gene engineering, and molecular/cellular biology. The individual will work closely with laboratory investigators and trainees to perform routine and advanced experimental procedures, maintain laboratory operations, and assist with data collection and analysis.

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About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

• Bachelors or Masters degree in science or related field (Biology, Neuroscience, Molecular Biology, Cell Biology, Biomedical Sciences, or a related scientific discipline) required 
• No experience required. One year of research experience preferred.
• Experience with human iPSC culture, neuronal differentiation, and stem cell-based disease modeling.
• Experience with CRISPR/Cas9 genome engineering, cloning, and lentiviral techniques.
• Familiarity with molecular and biochemical techniques including PCR, qPCR, western blotting, immunocytochemistry, and protein/RNA analyses.
• Experience with fluorescence microscopy and image analysis software is preferred.
• Strong quantitative and analytical skills with ability to interpret experimental data.

• Bachelors or Masters degree in science or related field (Biology, Neuroscience, Molecular Biology, Cell Biology, Biomedical Sciences, or a related scientific discipline) required 
• No experience required. One year of research experience preferred.
• Experience with human iPSC culture, neuronal differentiation, and stem cell-based disease modeling.
• Experience with CRISPR/Cas9 genome engineering, cloning, and lentiviral techniques.
• Familiarity with molecular and biochemical techniques including PCR, qPCR, western blotting, immunocytochemistry, and protein/RNA analyses.
• Experience with fluorescence microscopy and image analysis software is preferred.
• Strong quantitative and analytical skills with ability to interpret experimental data.

Compensation Statement

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58,661.00 - $80,211.02 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

Non-Bargaining Unit, 867 - Neurosciences - ISM, Icahn School of Medicine

• Maintenance, expansion, quality control, and differentiation of human induced pluripotent stem cells (iPSCs) and neuronal cultures.
• Performing gene engineering experiments, including CRISPR/Cas9 genome editing, cloning, transfection, lentiviral production, and validation of engineered cell lines.
• Conducting molecular biology experiments, including RNA extraction, qPCR, PCR, western blotting, immunocytochemistry, and protein/RNA analyses.
• Performing cellular and biochemical assays to characterize disease phenotypes and evaluate experimental outcomes.
• Assisting with experimental design, data collection, record keeping, and analysis of research results.
• Preparing reagents, maintaining laboratory inventories, ordering supplies, and ensuring proper laboratory organization and compliance with institutional safety protocols.
• Maintaining accurate laboratory notebooks and experimental records.
• Assisting in optimization and troubleshooting of experimental protocols.
• Collaborating with other laboratory personnel on ongoing research projects and contributing to general laboratory operations.
• Performs other related duties