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Downstream Process Jobs in Calabasas, CA (NOW HIRING)

Baker Hughes

Sales Advisor

Los Angeles, CA · On-site

Sales Advisor Are you passionate about driving process technology excellence in downstream refining? Do you enjoy solving complex technical challenges and partnering with customers to optimize ...

Baker Hughes

Sales Advisor

Los Angeles, CA · On-site

Sales Advisor Are you passionate about driving process technology excellence in downstream refining? Do you enjoy solving complex technical challenges and partnering with customers to optimize ...

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All JobsDownstream Process JobsDownstream Process Jobs in Calabasas, CA

Downstream Process information

See Calabasas, CA salary details

$14

$26

$37

How much do downstream process jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for downstream process in Calabasas, CA is $26.14, according to ZipRecruiter salary data. Most workers in this role earn between $20.87 and $29.81 per hour, depending on experience, location, and employer.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What job categories do people searching Downstream Process jobs in Calabasas, CA look for?

The top searched job categories for Downstream Process jobs in Calabasas, CA are:

What cities near Calabasas, CA are hiring for Downstream Process jobs?

Cities near Calabasas, CA with the most Downstream Process job openings:

Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Calabasas, CA as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 19% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $54,362 per year, or $26.1 per hour.

Sr. Technical Sales Specialist, Downstream Bioproduction (CA)

Thermo Fisher Scientific

Gardena, CA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 18 days ago

Key responsibilities

  • Meet or exceed assigned sales goals for downstream workflow products by maintaining growth and actively searching for new business opportunities within the territory.

  • Travel to customer sites for sales calls and presentations, and work closely with applications counterparts to move sales from evaluation to close.

  • Collaborate with customers and product management to forecast and communicate large order and shipment details.

Thermo Fisher Scientific rating

7.8

Company rating: 7.8 out of 10

Based on 430 frontline employees who took The Breakroom Quiz

171st of 547 rated manufacturers

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

Sell Thermo Fisher’s Downstream Workflow products to biotech and biopharma accounts for process development and manufacturing.

This highly valued individual contributor will model and act in alignment with Thermo Fisher Scientific’s values! This is an incredible opportunity for someone looking to play a key role in collaborating with an outstanding team in a high-growth, innovative Life Sciences company. Interested? Join us today!

Impact:

Successful sales performance directly contributes to achieving sales revenue targets; accurate forecasting through strong customer relationships permits accurate and timely production planning.

Territory:   This covers a territory that includes CA (southern california), UT, AZ, and NV. Given the primary location of the accounts, residency within soutthern california is required to facilitate customer engagement. No relocation assistance is provided.

Job Duties:

Meet or exceed assigned sales goals for downstream workflow products, including POROS, CaptureSelect and GIBCO products by maintaining growth and actively searching for new business opportunities within the territory.

Travel to customer sites for sales calls and presentations. Work closely with applications counterparts to move sales from evaluation to close.

Introduce/seed downstream workflow products in new processes in accounts while working closely with existing accounts to identify new opportunities.

Collaborate with customers and product management to forecast and communicate large order and shipment details.

Maintain and improve sales skills through technical and sales training. Proactively update SalesForce and Business Plans.

Attend tradeshows, conferences, and read trade journals to learn about company products.

Collaborate with sales colleagues in the territory that represents Thermo’s other BioProduction products, including Gibco Cell Culture Products, Single Use Products, and PCR and Sequencing-based Analytics Products, to help grow Thermo’s overall Bioproduction business.

Qualifications:

To perform this job optimally, an individual must satisfactorily perform each essential job duty. The requirements below represent the required knowledge, skills, and/or ability. Reasonable accommodations may be made to enable individuals with disabilities to perform essential functions.

Education:

  • Bachelor's or advanced degree (B.S, M.A, PhD. or equivalent experience) in Chemistry or related field.
  • Experience within Bioproduction or chromatography workflows is preferred
  • 5 plus years sales experience in biopharmaceutical market required.

Business Insight:

Seek sales opportunities and provide innovative solutions to customer needs using effective strategies.

Other Knowledge:

Positive technical skills are needed to discuss and support chromatography resins for biopharmaceutical process development and manufacturing groups. An ability to develop and maintain positive relationships by learning the background of the accounts and key customers, interpreting customers' needs, and providing solutions. Positive analytical skills are essential to analyze territory sales data and technical information. Requires the ability to perform independently and as part of a team.

Established sales history and relationships with the downstream process development

  • Demonstrated technical expertise across the downstream bioprocessing workflow, including chromatography resins, process liquids and production solutions, and production chemicals and services supporting biopharmaceutical process development and manufacturing applications
  • Proven ability to build and maintain strong customer relationships through:
  • Developing a comprehensive understanding of customer accounts, manufacturing processes, and stakeholder priorities
  • Assessing and interpreting customer process and operational needs
  • Delivering tailored technical and commercial solutions across the downstream workflow
  • Strong analytical capabilities with experience evaluating:
  • Territory sales performance, market dynamics, and growth opportunities
  • Technical data, manufacturing workflows, and application-specific information
  • Self-motivated professional with the ability to work effectively both independently and within cross-functional and matrixed team environments
  • Established track record of sales success and strategic relationship management within downstream bioprocessing, process development, and biopharmaceutical manufacturing organizations

Ability to effectively position integrated downstream solutions spanning chromatography, buffers and process liquids, production chemicals, and manufacturing support services to optimize customer process performance and scalability

Compensation and Benefits

The salary range estimated for this position based in California is $131,150.00–$168,650.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs

  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement

  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

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