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Downstream Manufacturing Associate Jobs in Riverside, CA

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ob description Upstream, Formulation & Downstream Manufacturing Associate Location: Tustin, CA Industry: Biopharmaceutical Manufacturing Schedule: 5:00PM - 2:00AM Employment Type: Full-Time Position ...

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ob description Upstream, Formulation & Downstream Manufacturing Associate Location: Tustin, CA Industry: Biopharmaceutical Manufacturing Schedule: 5:00PM - 2:00AM Employment Type: Full-Time Position ...

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Downstream Manufacturing Associate information

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How much do downstream manufacturing associate jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for downstream manufacturing associate in Riverside, CA is $21.74, according to ZipRecruiter salary data. Most workers in this role earn between $17.07 and $24.33 per hour, depending on experience, location, and employer.

What is a downstream manufacturing associate?

Downstream Manufacturing Associates are professionals who work in the later stages of biopharmaceutical and biotechnology manufacturing processes. Their main responsibilities involve purifying and processing biological products after the initial production phase, often using techniques like filtration and chromatography. They ensure the quality and safety of the final product by following strict protocols and maintaining detailed documentation. Downstream associates often work in cleanroom environments and collaborate with other teams to meet production goals.

What are the key skills and qualifications needed to thrive as a downstream manufacturing associate?

To thrive as a Downstream Manufacturing Associate, you need a solid understanding of bioprocessing, protein purification, and GMP (Good Manufacturing Practice) standards, often gained through a degree in life sciences or related field. Familiarity with chromatography systems, filtration technologies, and process automation tools is typically required, alongside relevant safety certifications. Attention to detail, teamwork, and strong problem-solving skills are valued soft skills in this role. These qualifications are essential for ensuring the efficient, safe, and compliant production of biopharmaceutical products.

What are some typical challenges faced by downstream manufacturing associates, and how can they be addressed?

Downstream Manufacturing Associates often encounter challenges such as maintaining strict adherence to GMP (Good Manufacturing Practices), troubleshooting equipment issues, and ensuring consistent product quality during purification and filtration processes. These challenges can be addressed through thorough training, clear documentation, and effective communication within the team. Collaborating closely with upstream teams and quality control helps resolve issues quickly and ensures smooth workflow. Staying detail-oriented and proactive in identifying potential bottlenecks also contributes to success in this role.

What is the difference between Downstream Manufacturing Associate vs Upstream Manufacturing Associate?

AspectDownstream Manufacturing AssociateUpstream Manufacturing Associate
Primary ResponsibilitiesPurifies, filters, and processes final product batchesPrepares raw materials and manages initial production stages
Work EnvironmentCleanroom, laboratory, manufacturing floorManufacturing plant, laboratory, production line
Required CertificationsGMP training, OSHA safety certificationsGMP training, OSHA safety certifications
Industry UsagePharmaceutical, biotech manufacturingPharmaceutical, biotech manufacturing

Downstream Manufacturing Associates focus on final product purification and processing, while Upstream Manufacturing Associates handle raw material preparation and initial production. Both roles are essential in biopharmaceutical manufacturing, often requiring similar certifications and working in related environments.

What cities near Riverside, CA are hiring for Downstream Manufacturing Associate jobs?

Cities near Riverside, CA with the most Downstream Manufacturing Associate job openings:

Infographic showing various Downstream Manufacturing Associate job openings in Riverside, CA as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 28% Part Time, 1% Temporary, and 2% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $45,217 per year, or $21.7 per hour.

Biopharmaceutical Manufacturing Associate

Tustin, CA • On-site

Kinetic Personnel Group
Recruiting and Staffing Services • 501 - 1,000 employees

$20 - $21/hr

Full-time

Posted 4 days ago

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Job description

ob description

Job description

Upstream, Formulation & Downstream Manufacturing Associate

Location: Tustin, CA
Industry: Biopharmaceutical Manufacturing
Schedule: 5:00PM – 2:00AM
Employment Type: Full-Time

Position Summary

A leading biopharmaceutical manufacturing company in Tustin, CA is seeking motivated Manufacturing Associates to support Upstream, Formulation, and Downstream manufacturing operations. These positions are responsible for executing manufacturing activities in a controlled GMP environment while following established procedures, safety requirements, and quality standards.

Multiple shifts are available, including 1st, 2nd, and 3rd shifts. Candidates with a degree in Biology, Biochemistry, Biotechnology, Microbiology, or another related Life Science discipline are encouraged to apply.

Key Responsibilities

Upstream Manufacturing

  • Support cell culture and upstream bioprocessing activities.
  • Prepare and stage materials, equipment, and solutions for manufacturing operations.
  • Assist with media and buffer preparation.
  • Monitor and document manufacturing processes and equipment readings.
  • Perform sampling and in-process testing as required.
  • Follow SOPs, batch records, GMP requirements, and safety procedures.
  • Maintain clean and organized manufacturing areas.
  • Accurately document manufacturing activities in accordance with GMP requirements.

Formulation Manufacturing

  • Support formulation and preparation of biopharmaceutical products.
  • Weigh, measure, and prepare raw materials and components according to approved procedures.
  • Operate manufacturing equipment following established SOPs.
  • Perform equipment setup, cleaning, and sanitization.
  • Conduct in-process checks and sampling.
  • Complete batch documentation and manufacturing records accurately.
  • Follow aseptic and GMP practices as required.

Downstream Manufacturing

  • Support downstream purification and processing activities.
  • Assist with filtration, chromatography, centrifugation, and related manufacturing processes.
  • Prepare and stage materials and equipment for production.
  • Monitor equipment and process parameters.
  • Collect and document process samples.
  • Perform equipment setup, cleaning, and sanitization.
  • Follow SOPs, batch records, GMP requirements, and safety procedures.

Qualifications

  • Bachelor's degree in Biology, Biochemistry, Biotechnology, Microbiology, Chemistry, or another related Life Science discipline required.
  • Manufacturing, laboratory, pharmaceutical, biotechnology, or biopharmaceutical experience preferred.
  • Understanding of basic biological and laboratory principles.
  • Ability to accurately follow written procedures and SOPs.
  • Strong attention to detail and documentation skills.
  • Ability to work effectively in a team-oriented manufacturing environment.
  • Ability to work multiple shifts, including evenings, nights, weekends, or overtime as required.
  • Ability to work in a controlled/GMP manufacturing environment.
  • Strong communication and organizational skills.
  • Ability to learn manufacturing equipment, processes, and procedures quickly.

Preferred Experience

  • GMP or cGMP experience.
  • Biopharmaceutical or pharmaceutical manufacturing experience.
  • Cell culture or upstream processing experience.
  • Formulation or solution preparation experience.
  • Downstream purification experience.
  • Experience with batch records and manufacturing documentation.
  • Experience working in a cleanroom or controlled manufacturing environment.

Physical Requirements

  • Ability to stand and walk for extended periods.
  • Ability to wear required PPE and cleanroom garments.
  • Ability to lift and move materials and equipment as required.
  • Ability to perform repetitive manufacturing activities.
  • Ability to work in a controlled manufacturing environment.

Why Join Us?

This is an excellent opportunity for a Life Science graduate to build hands-on experience in biopharmaceutical manufacturing and develop expertise across Upstream, Formulation, or Downstream processing. Successful candidates will work in a regulated GMP environment supporting the production of high-quality biopharmaceutical products.