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Dna Encoded Chemistry Jobs (NOW HIRING)

$150 - $200/hr

Leveraging modern technologies like AI/ML and DNA-Encoded Libraries, you will help solve complex ... PhD in Medicinal Chemistry, Organic Chemistry, or a related discipline.* **Experience:** A minimum ...

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Dna Encoded Chemistry information

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How much do dna encoded chemistry jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for dna encoded chemistry in the United States is $22.26, according to ZipRecruiter salary data. Most workers in this role earn between $18.27 and $24.52 per hour, depending on experience, location, and employer.

What is DNA encoded chemistry?

DNA encoded chemistry is a technique used in drug discovery where small molecules are attached to unique DNA sequences, creating large libraries of compounds that can be screened simultaneously. The DNA acts as a barcode, allowing researchers to identify which compounds interact with a biological target by sequencing the DNA tags. This method accelerates the discovery of potential drug candidates and enables the efficient testing of millions to billions of molecules in a single experiment.

What are the key skills and qualifications needed to thrive in DNA encoded chemistry?

To thrive as a DNA Encoded Chemistry Scientist, you need a strong background in organic/medicinal chemistry, molecular biology, and experience with DNA-encoded library (DEL) technology, typically supported by an advanced degree in chemistry or related fields. Familiarity with high-throughput screening platforms, next-generation sequencing, and data analysis software is essential. Strong problem-solving, attention to detail, and collaboration skills help differentiate top performers in this interdisciplinary role. These competencies are crucial for designing, executing, and interpreting complex experiments that accelerate drug discovery.

What are the typical challenges faced by professionals working in DNA encoded chemistry, and how can job seekers prepare for them?

Professionals in DNA-encoded chemistry often face challenges related to the complexity of library design, synthesis fidelity, and decoding the resulting data. Maintaining high-quality control throughout chemical synthesis and robustly analyzing large datasets are critical aspects of the role. Job seekers can prepare by gaining strong laboratory skills, familiarizing themselves with automation technologies, and developing competency in data analysis tools commonly used in this field. Additionally, effective collaboration with multidisciplinary teams, including chemists, biologists, and data scientists, is vital for success.

What is the difference between Dna Encoded Chemistry vs Dna Sequencing Technician?

AspectDna Encoded ChemistryDna Sequencing Technician
Required CredentialsBiochemistry, Molecular Biology degrees, certifications in lab techniquesBiology, Molecular Biology degrees, sequencing certifications
Work EnvironmentResearch labs, biotech companies, pharmaceutical labsSequencing facilities, research labs, biotech companies
Employer & Industry UsageUsed in DNA synthesis, drug development, genetic researchPrimarily in DNA sequencing, genetic analysis, diagnostics

While both roles involve working with DNA technologies, Dna Encoded Chemistry focuses on synthesizing and encoding DNA for various applications, whereas Dna Sequencing Technicians specialize in sequencing DNA samples to analyze genetic information. Understanding these differences helps clarify career paths and job expectations in the biotech industry.

What other helpful pages are available for Dna Encoded Chemistry?

Other pages related to Dna Encoded Chemistry:

Infographic showing various Dna Encoded Chemistry job openings in the United States as of September 2026, with employment types broken down into 3% Internship, 1% As Needed, 70% Full Time, 23% Part Time, 1% Temporary, and 2% Contract. Highlights an 83% Physical, 1% Hybrid, and 16% Remote job distribution, with an average salary of $46,292 per year, or $22.3 per hour.

Senior Research Associate, DNA Encoded Library Technology ~ Contract

Brisbane, CA • On-site

$119K - $139K/yr

Full-time

Re-posted 23 days ago


Key responsibilities

  • Design and validate novel DNA-encoded library (DEL) builds.

  • Develop new DNA-compatible chemical transformations to expand DEL chemical space.

  • Construct DEL libraries to support in-house library production and collaborate with external partners on DEL synthesis and hit follow-up strategies.


Job description

Company
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix's dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease.
Senior Research Associate, DNA Encoded Library Technology - Nurix Brisbane
Position
We are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the design and synthesis of DNA-encoded libraries (DELs). This hands-on position offers the opportunity to shape Nurix's DEL-based lead discovery platform, working at the interface of chemistry, biology, and automation. Key responsibilities:
  • Design and validate novel DEL library builds.
  • Develop and bring in new DNA-compatible chemical transformations that can widen the DEL chemical space.
  • Construct DEL libraries to support the in-house library production efforts.
  • Work with external partners to support our DEL synthesis and hit follow up strategies.
  • Engage in cross-functional team discussions that support DEL screening, data analysis, machine learning and hit-optimization.
  • Contribute to platform automation and technology development efforts.
  • Present results, document workflows, and contribute to scientific and strategic planning within the Discovery Chemistry organization.

Education and Experience
  • B.S. or higher in Chemistry, Biochemistry, or Medicinal Chemistry with 5 years of industrial experience (title determined by experience).
  • Strong background in synthetic organic chemistry.
  • Hands-on laboratory experience synthesizing DNA encoded libraries.
  • Familiar with the overall DNA-Encoded Library Technology workflow operations.
  • Experience analyzing and purifying DNA-conjugates using common analytical tools (LCMS/HPLC).

Added Qualifications
  • Experience working in the drug discovery field - drug design, synthesis, and SAR based hit-to-lead optimization.
  • Experience working with high-throughput analytical and purification systems relevant to DEL-applications.
  • Experience working with molecular biology tools (PCR, qPCR, Western Blot).

Fit with Nurix Culture and Values
  • Collaborative and team-oriented, eager to share expertise and learn from others.
  • Solution-driven with a hands-on and resourceful approach.
  • Adaptable and comfortable in a fast-paced, interdisciplinary environment.
  • Committed to scientific excellence and the shared goals of the team.

Location: Brisbane, CA
Salary Range: $119K - $139K
Application Process
Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US.
Note to Employment Agencies: Please do not forward any agency resumes. Nurix will not be responsible for fees related to unsolicited resumes.
Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/).