Director Preclinical Development Jobs in Paramus, NJ

The Associate Director role involves supporting Pharmacokinetics (PK) and Pharmacokinetics/Pharmacodynamics (PK/PD) requirements for early-stage drug discovery and IND projects. Responsibilities include providing input and oversight for preclinical in vivo studies, coordinating with and influencing scientific teams conducting these studies, managing nonclinical Pharmacokinetics studies, analyzing and presenting PK/PD data to project teams and senior management, and preparing summary reports for regulatory submissions.

When & where: Work Location: Tarrytown, NY Work model/flexibility: 4 days per week onsite

Discover your role: Serving as a subject matter expert on Preclinical PK/PD within Discovery-stage project teams and guiding the design of preclinical PK/pharmacology studies. Collaborating with various internal groups such as Therapeutic Proteins, Therapeutic Function Areas, Assay Development, Precision Medicine, Preclinical Operations, and PPK/PD management to develop and execute PK strategies for projects. Effectively communicating project team queries, expectations, and timelines to management. Conducting and reporting PK/PD analyses based on data from preclinical studies. Working closely with Toxicology, Pathology, Clinical Pharmacology, and Quantitative Pharmacology teams within the Drug Safety and Pharmacometrics department to deliver data and regulatory documents supporting project progression. Maintaining current knowledge of scientific literature, regulatory guidance, and best practices related to PK/PD.

This role requires: PhD in Pharmacology, Pharmacokinetics, Biology/Molecular Biology, or Biochemistry with more than 8 to 10 years of relevant experience in biotech or pharma. Deep theoretical and applied understanding of PK and PD to interpret the pharmacology and biology of therapeutic proteins. Experience with other modalities such as siRNA, CRISPR-based therapeutics, and cell therapies is highly beneficial. Proven ability to plan, coordinate, lead PK and/or PK/PD studies, and analyze related data. Familiarity with PK/PD (e.g., WinNonLin), data visualization and AI software and experience writing scientific reports and regulatory summaries.

Does this sound like you?

Please be advised that at Regeneron, we believe we do our best work when we are together.

For that reason, many roles are required to be performed on-site.

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans


• equity awards


• pension or retirement benefits


• 401(k) company match


• health and wellness programs


• fitness centers


• insurance benefits (e.g. medical, dental, vision, life and disability)


• paid time off


• family support benefits

Salary Range (annually) $176,100.00 - $287,300.00

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.