Director Portfolio Operations Jobs in Delaware (NOW HIRING)

Location: US, Wilmington
Function: Marketing
Travel: Approximately 10-20%
At AstraZeneca, we are driven by the opportunity to transform patients' lives through science. We are seeking a Director of Life Cycle Marketing to join our growing Immunology business in a highly visible strategic role supporting the future of our expanding portfolio.
This is an exciting opportunity for a seasoned marketing leader who combines strong commercial insight with a passion for innovation, launch excellence, and cross-functional collaboration. As a member of the US Immunology Marketing Leadership Team, you will help shape brand strategy, drive US launch readiness, and translate clinical and scientific opportunity into meaningful commercial impact.
In this role, you will serve as the strategic lead for AstraZeneca's immunology pipeline, with responsibility for shaping brand strategy and US launch readiness efforts for all future formulations and indications for the treatment of Lupus.
Reporting to the Senior Marketing Director, Immunology, you will partner closely with colleagues across US Medical, Commercial, Insights, Operations, and Global teams to ensure successful pre-launch and launch execution across the portfolio.
What you'll do
You will lead the development and execution of pre-launch through commercial launch strategies for new and upcoming indications within the US immunology portfolio. This includes setting strategy, building milestone-based plans, and coordinating key activities across the business to support successful launches.
Your responsibilities will include developing the US brand market plan, shaping HCP commercial strategy, guiding patient journey and engagement planning, and driving insight generation through qualitative and quantitative research with healthcare professionals, patients, and payers. You will also support advisory board development, forecasting, and supply chain readiness.
A key aspect of the role will be serving as the liaison between the US and Global organizations, ensuring plans are aligned, timely, and connected to the broader immunology portfolio strategy. You will also lead recommendations for the go-to-market model, partnering with marketing and field leadership on customer segmentation, field deployment, and execution planning.
Working across a highly matrixed organization, you will collaborate with teams in Marketing, Sales, GPPS, Pricing & Market Access, Medical Affairs, Regulatory, and Operations to deliver integrated and effective launch plans. You will also build and present business cases to support Phase 3, real-world evidence, and post-launch studies, as well as broader commercial investment decisions through insight generation, market analysis, forecasting, and commercial modeling.
In addition, you will represent AstraZeneca at congresses and conferences, helping shape the roadmap for HCP engagement across pipeline assets, while partnering with in-line marketing teams to ensure that key milestones, deliverables, and launch activities are seamlessly integrated across the organization.
Minimum Qualifications

• Bachelor's degree in business or a related field.
• 8+ years of experience in the pharmaceutical or healthcare industry, including 5+ years in pharmaceutical marketing or a related function such as managed markets, pharmaceutical sales, market research/analytics, strategic planning, or relevant agency experience.
• Experience supporting or leading work across the pharmaceutical product development-to-commercialization process.
• Ability and willingness to travel 10-20%.

Preferred Qualifications

• Advanced degree in Business, Marketing, or a scientific discipline.
• 4+ Years of immunology experience
• 2+ years of Rheumatology or Dermatology experience
• Experience in cross-channel and cross-customer marketing.
• Experience leading or supporting early brand lifecycle or launch strategy.
• 3+ years of people leadership experience.
• Experience with budget management and/or platforms such as Veeva, Coupa, or Viewpoint.

Pay Transparency
The annual base pay for this position could range from $180,693 - $233,000 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employees will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca, we are driven by our commitment to deliver accelerated growth for AstraZeneca and make people's lives better. We thrive in our often-intense environment by seeking out new challenges and working towards innovative solutions. Here you can build a long-term career with global knowledge opportunities while positively impacting local communities.
Ready to step up? Apply now to join our team!
Why AstraZeneca
At AstraZeneca, you'll join a team that is committed to scientific excellence, collaborative leadership, and meaningful innovation. This role offers the chance to influence critical launch decisions, partner with senior leaders across the business, and play a direct role in helping bring important medicines to patients.
If you are a strategic and commercially minded marketing leader looking to shape the future of Immunology at AstraZeneca, we would welcome your interest.
Date Posted
16-Jul-2026
Closing Date
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.