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Director Of Research Informatics I information

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How much do director of research informatics i jobs pay per year?

As of Sep 9, 2026, the average yearly pay for director of research informatics i in the United States is $117,282.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,000.00 and $136,000.00 per year, depending on experience, location, and employer.

What is a director of research informatics I?

A Director of Research Informatics I is a leadership role responsible for overseeing the development, implementation, and management of informatics solutions to support research activities within an organization. This person coordinates teams that handle data collection, analysis, storage, and sharing for research projects, ensuring compliance with regulatory standards and data integrity. They work closely with researchers, IT professionals, and administrators to optimize research workflows and leverage technology to advance scientific goals. The 'I' typically designates an entry or first-level director position in a larger informatics leadership structure.

What are the key skills and qualifications needed to thrive as a director of research informatics I?

To thrive as a Director Of Research Informatics I, you need a strong background in biomedical informatics, data management, and leadership, typically with an advanced degree in a related field. Familiarity with research data platforms (such as REDCap), database systems, and compliance certifications like HIPAA are commonly required. Outstanding project management, communication, and problem-solving skills help drive collaboration across research teams and ensure alignment with institutional goals. These competencies are crucial for overseeing complex research data operations and supporting high-impact scientific discovery.

What are the typical challenges faced by a director of research informatics I when implementing new data systems within research teams?

A Director of Research Informatics I often encounters challenges such as aligning diverse research teams on standardized data practices, integrating new informatics platforms with legacy systems, and ensuring data security and compliance with regulations. Navigating varying technical proficiency among team members and managing stakeholder expectations also require strong communication and change management skills. Success in this role depends on fostering collaboration between IT, researchers, and leadership to ensure smooth adoption and maximize the value of informatics solutions.

What are popular job titles related to Director Of Research Informatics I jobs?

For Director Of Research Informatics I jobs, the most frequently searched job titles are:

Director, Research Informatics

South San Francisco, CA • On-site

Denali Therapeutics
Scientific Research and Development Services • 201 - 500 employees
Learn more about Denali Therapeuticsexternal

$204K - $265K/yr

Full-time

Medical, Retirement

Re-posted 13 hours ago

Key responsibilities

  • Owns the strategy, roadmap, and operational delivery of Research Informatics platforms and AI integration.

  • Leads and develops a team responsible for platform support, configuration, validation, and continuous improvement.

  • Partners with scientists and lab operations to translate requirements into scalable platform solutions.

Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Research Informatics is responsible for the scientific data platforms and internal software that underpin the full research and development pipeline at Denali Therapeutics. This function owns the strategy, implementation, and ongoing support of the digital tools that enable scientists to register molecular entities and to track, analyze, and document associated experimental data across the full lifecycle, from early discovery through translational and development handoffs. These tools include Denali's Electronic Laboratory Notebook (ELN), the internal experiment data management platforms that underpin our scientific documentation, and the AI capabilities that unlock the full value of our data.
The Director of Research Informatics will lead this function, serving as the strategic and operational owner of our scientific data platforms, including Benchling, Dotmatics, and our internal software and AI tool integration. This individual will define the informatics roadmap, drive stakeholder alignment behind it, and build a high-caliber engineering team, while serving as a trusted technical partner to Discovery, enterprise IT, and other operational leadership. This is a hands-on leadership role: the Director will set technical direction and make software architecture and design-space decisions, not simply manage from a distance.
Key Accountabilities / Core Job Responsibilities
  • Owns the strategy, roadmap, and operational delivery of Research Informatics, including Benchling, Dotmatics, internal software systems, and AI integration.
  • Leads and grows a team responsible for platform support, configuration, validation, and continuous improvement across Discovery, Development, and Technical Operations.
  • Partners with scientists and lab operations leads to translate business and scientific requirements into scalable, well-engineered platform solutions.
  • Serves as subject matter expert on ELN capabilities and experiment data workflows, advising on platform selection and integration strategy.
  • Communicates platform strategy, status, and risk clearly to senior stakeholders, from group leaders to senior management.
  • Engages hands-on in configuration and platform build work, alongside strategic oversight.
  • Drives vendor relationships and manages platform migrations, escalations, and contract performance.
  • Explores and integrates next-generation, AI-driven experiment capture concepts, including passive documentation architectures that reduce manual interface dependency while preserving compliant, attributable records.
  • Owns roadmap prioritization and backlog decisions, balancing input from scientific, engineering, and IT stakeholders.
  • Leads direct report(s) through annual goal setting, growth planning, adherence to company policies, maintains training compliance, and provides ongoing feedback on growth, development, and areas of improvement.

Qualifications/Skills
  • Typically requires a Bachelor's degree in a technical field (computer science, data science, engineering, or related); advanced degree preferred.
  • Typically requires 10+ years building and delivering software solutions, including 7+ years in pharma, biotech, or life sciences supporting laboratory informatics or scientific platforms.
  • Typically requires 8+ years of people management experience, including building and growing engineering teams.
  • Hands-on expertise with scientific data platforms (e.g., Benchling, Dotmatics) and experience leading ELN/registry migrations preferred.
  • Experience partnering with enterprise IT on security, licensing, and infrastructure, and familiarity applying AI/ML workflows to biological or chemical data, preferred.

Salary Range: $204,000.00 to $265,000.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers
This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

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