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Director Engineering Cell Therapy Jobs (NOW HIRING)

System One

Biologist

Boston, MA · On-site

$48.69 - $57.28/hr

Design and engineer novel cell lines in iPSCs, tumor cell lines, and other immortalized and primary cell types to support allogeneic cell therapy programs * Generate stable engineered cell lines ...

System One

Biologist

Boston, MA · On-site

$48.69 - $57.28/hr

Design and engineer novel cell lines in iPSCs, tumor cell lines, and other immortalized and primary cell types to support allogeneic cell therapy programs * Generate stable engineered cell lines ...

Bayer

$22 - $24.50/hr

... Therapy Cell Culture, you are a subject matter expert (SME) responsible for the clinical ... Bachelor's degree in a relevant life science or engineering discipline (e.g., Biotechnology, Cell ...

Bayer

$22 - $24.50/hr

... Therapy Cell Culture, you are a subject matter expert (SME) responsible for the clinical ... Bachelor's degree in a relevant life science or engineering discipline (e.g., Biotechnology, Cell ...

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Director Engineering Cell Therapy information

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$73K

$194.7K

$254K

How much do director engineering cell therapy jobs pay per year?

As of Sep 14, 2026, the average yearly pay for director engineering cell therapy in the United States is $194,709.00, according to ZipRecruiter salary data. Most workers in this role earn between $141,500.00 and $253,000.00 per year, depending on experience, location, and employer.

What does a director engineering cell therapy do?

A Director of Engineering in Cell Therapy oversees the development, optimization, and implementation of processes and technologies used in cell therapy manufacturing and research. They lead engineering teams, ensure regulatory compliance, and collaborate with scientists and other departments to scale up production while maintaining product quality and safety. Their role is critical in bringing innovative cell therapy treatments from the laboratory to clinical and commercial settings.

What are the key skills and qualifications needed to thrive as a director engineering cell therapy?

To thrive as a Director of Engineering in Cell Therapy, you need advanced knowledge of cell therapy manufacturing, leadership experience, and a degree in engineering, biotechnology, or a related field. Familiarity with GMP regulations, bioprocessing equipment, automation systems, and quality management certifications (such as Six Sigma or Lean) is often required. Strategic thinking, strong communication, and the ability to lead multidisciplinary teams are crucial soft skills for this role. These competencies ensure the safe, efficient, and compliant development of innovative cell-based therapies in a highly regulated environment.

What are the main challenges a director engineering cell therapy typically faces when scaling up manufacturing processes?

A Director of Engineering in Cell Therapy often encounters challenges related to transitioning processes from small-scale laboratory settings to large-scale, compliant manufacturing environments. This includes ensuring product consistency, meeting strict regulatory requirements, and managing cross-functional teams to coordinate technology transfer. Additionally, keeping up with rapid advancements in cell therapy technologies and integrating automated systems while maintaining high quality standards can be demanding. Success in this role requires excellent project management skills and effective collaboration with R&D, quality assurance, and operations teams.

What are popular job titles related to Director Engineering Cell Therapy jobs?

For Director Engineering Cell Therapy jobs, the most frequently searched job titles are:

Biologist

Boston, MA • On-site

System One
Business Consulting Services • 5 - 10K employees
Learn more about System Oneexternal

$48.69 - $57.28/hr

Contractor

Medical, Dental, Vision, Life, Retirement

Re-posted 29 days ago

Job description

Job Title: Biologist Location: Boston, MA Contractor Work Model: Onsite – onsite Hours: M-F 9am-5pm Compensation: $48.69 - $57.28/hr Type: Contract, Potential for extension or conversion to permanent Overview As a Scientist in Cell Engineering and Assay Development, you will engineer novel cell lines and develop the in vitro assays used to characterize them in support of our allogeneic cell therapy programs. You will design genetic constructs and mRNA, generate engineered cell lines using viral vectors and transient mRNA-based expression, and build cell-based assays to evaluate the function of engineered cells. You will work closely with cross-functional teams to advance cell therapy programs from discovery through preclinical development. Responsibilities

  • Design and engineer novel cell lines in iPSCs, tumor cell lines, and other immortalized and primary cell types to support allogeneic cell therapy programs
  • Generate stable engineered cell lines using lentiviral transduction and other viral vector systems
  • Design genetic constructs and mRNA for stable and transient gene expression, including knock-in, knockout, and reporter strategies
  • Perform transient mRNA-based expression to rapidly prototype and validate cell engineering strategies
  • Establish clonal engineered cell lines through cell sorting (FACS) and single-cell cloning
  • Develop, optimize, and execute cell-based assays to characterize engineered cells, including live-cell analysis on the Incucyte platform
  • Design and run in-depth, multi-parameter flow cytometry panels to phenotype engineered cells and assess immune checkpoint receptor expression
  • Evaluate the functional impact of genetic modifications on engineered cell phenotype and function
  • Design and execute experiments, analyze data, and interpret results to evaluate the performance of engineered cells in vitro
  • Communicate experimental data effectively through written reports and oral presentations.
  • Demonstrate flexibility and motivation to learn and apply new technologies for cell engineering and assay development.
Qualifications Required:
  • Bachelor’s degree in Cell Biology, Molecular Biology, Immunology, or a related field plus 5 years of relevant experience in biotechnology, pharmaceutical industry, or academic research.
  • Master’s degree in Cell Biology, Molecular Biology, Immunology, or a related field plus 2 years of relevant experience in biotechnology, pharmaceutical industry, or academic research.
  • Hands-on experience with lentiviral cell line generation is required.
Additional Skills/Preferences:
  • Experience engineering iPSCs and tumor cell lines
  • Proficiency in construct design and mRNA design
  • Experience with cell engineering using viral vectors and transient mRNA-based expression
  • In-depth flow cytometry expertise, including panel design, cell sorting (FACS), and multi-parameter data analysis
  • Working knowledge of immune checkpoint receptor biology
  • Experience with live-cell analysis platforms such as Incucyte and xCELLigence
  • Proficient in developing in vitro cell-based assays, including work with human cell lines and primary cells
  • Strong analytical, problem-solving, and decision-making skills.
  • Excellent interpersonal and communication skills.
  • Ability to work independently and collaboratively within a team environment.

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. #M- #LI- Ref: #558-Scientific

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About System One

Sourced by ZipRecruiter

System One helps employers get work done more efficiently and economically without compromising quality. Over our 35+ year history, we've helped connect thousands of talented people with innovative companies. The excitement of a perfect fit motivates us every single day.

Industry

Business consulting services and recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Pittsburgh, PA, US

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