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Computer System Validation Jobs in Houston, TX (NOW HIRING)

EBryit Inc

Computer Technician

Rosenberg, TX · On-site

$18 - $21/hr

Imaging, data migration, troubleshooting of computer systems. * Naming a computer and joining a ... Valid Drivers license and State minimum auto insurance. Job Type: Temporary Long term.

Sidram Technologies

Validation Engineer

Houston, TX · On-site

Client- Haliburton FPGA Design & Validation Engineer (Oil & Gas Systems) Houston, TX, USA Long term As an FPGA Engineer in our Oil & Gas division, you will develop high-reliability digital systems ...

YO AI Labs

Computer Systems Analyst - Remote

Houston, TX · Remote

$60 - $120/hr

Design UI/UX solutions and systems using Figma . * Apply strong typography, layout, and visual hierarchy principles. * Review designs and provide clear, constructive feedback. * Document design ...

Netsync Network Solutions

Computer Technician

Houston, TX · On-site

$17.50 - $23.25/hr

Manage and update support cases in Customer, Netsync and OEM systems. * Work on site hardware ... High School Diploma or Equivalent, CompTIA A+ or extensive break-fix experience, Valid Driver ...

Netsync Network Solutions

Computer Technician

Houston, TX · On-site

$17.50 - $23.25/hr

Manage and update support cases in Customer, Netsync and OEM systems. * Work on site hardware ... High School Diploma or Equivalent, CompTIA A+ or extensive break-fix experience, Valid Driver ...

Netsync Network Solutions

Computer Technician

Houston, TX · On-site

$17.50 - $23.25/hr

Manage and update support cases in Customer, Netsync and OEM systems. * Work on site hardware ... High School Diploma or Equivalent, CompTIA A+ or extensive break-fix experience, Valid Driver ...

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All JobsComputer System Validation JobsComputer System Validation Jobs in Houston, TX

Computer System Validation information

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How much do computer system validation jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for computer system validation in Houston, TX is $51.87, according to ZipRecruiter salary data. Most workers in this role earn between $39.95 and $61.54 per hour, depending on experience, location, and employer.

What is a computer system validation?

A Computer System Validation (CSV) job involves ensuring that computer systems used in regulated industries, such as pharmaceuticals and medical devices, meet compliance and regulatory requirements. CSV professionals develop and execute validation protocols to confirm that software, hardware, and processes function as intended and maintain data integrity. They work with quality assurance, IT, and regulatory teams to document compliance with standards like FDA 21 CFR Part 11 and GxP. This role is critical in maintaining system reliability, product quality, and patient safety.

What are the key skills and qualifications needed to thrive in computer system validation, and why are they important?

To excel in Computer System Validation, candidates typically need a background in computer science, engineering, or life sciences, with expertise in validating software and systems in regulated environments such as pharmaceuticals or medical devices. Familiarity with tools like validation documentation software, GAMP 5 guidelines, FDA 21 CFR Part 11 regulations, and potentially certifications like CSV Professional or Six Sigma is highly valued. Strong attention to detail, analytical thinking, and effective communication skills help professionals work collaboratively and document findings precisely. These abilities ensure compliance, data integrity, and the reliability of computerized systems critical to safety and quality.

What are some typical challenges faced in computer system validation roles?

Professionals in Computer System Validation often encounter challenges such as keeping up with evolving regulatory requirements, ensuring complete and accurate documentation, and coordinating with cross-functional teams to implement validation protocols. Balancing thoroughness with project deadlines can also be demanding, as every validation step must stand up to external audits. However, these challenges provide valuable experience, strengthen project management abilities, and emphasize teamwork—key attributes that support career advancement into validation leadership or quality assurance roles.

Is computer system validation a good field?

Computer System Validation (CSV) is a vital part of regulated industries like pharmaceuticals and biotech, ensuring that computer systems meet quality and compliance standards. It offers opportunities for professionals with skills in validation protocols, regulatory requirements, and tools like GxP and 21 CFR Part 11. The field provides steady employment, career growth, and the chance to work on critical quality assurance processes.

What are the most commonly searched types of Computer System Validation jobs in Houston, TX?

The most popular types of Computer System Validation jobs in Houston, TX are:

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For Computer System Validation jobs in Houston, TX, the most frequently searched job titles are:

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The top searched job categories for Computer System Validation jobs in Houston, TX are:

What cities near Houston, TX are hiring for Computer System Validation jobs?

Cities near Houston, TX with the most Computer System Validation job openings:

Computer System Validation jobs near you
Infographic showing various Computer System Validation job openings in Houston, TX as of August 2026, with employment types broken down into 87% Full Time, and 13% Contract. Highlights an 81% In-person, 13% Hybrid, and 6% Remote job distribution, with an average salary of $107,895 per year, or $51.9 per hour.

Quality Assurance Validation Specialist II

Immatics NV

Houston, TX • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 22 days ago

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
  • Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
  • Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
  • Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview
We are seeking a Quality Assurance Validation Specialist II to support our Global Quality Operations team. The QA Validation Specialist II will be responsible for providing QA oversight of regulated assets and business processes within the Validation Lifecycle Management System (VLMS), ensuring compliance with the Quality Management System (QMS) and GMP requirements. This role will also serve as a Subject Matter Expert (SME) in biopharmaceutical quality and as an on-site QA representative within the U.S. QA Validation team.
Schedule: 8:00 AM - 5:00 PM; Monday to Friday; On-site
Reports to: Senior Manager, Quality Assurance Validation
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477
Basic Qualifications:
  • Bachelor Degree in Engineering, Life Sciences, Computer Science or related.
  • At least three years' experience in a related role.
  • Possess scientific, technical background with experience in Biotechnology, Engineering, Computer Science or related field as well as work experience in related Biopharma industry or similar regulated settings.
  • Advanced understanding of Validation Lifecycle Pillars, which may include equipment lifecycle management, equipment qualification execution, equipment operation, equipment maintenance, workflows incl. GxP Computerized System Validation (CSV), Qualification phases such as IQ, OQ, PQ, Manufacturing Process Validation and Continued Process Verification.
  • Quality Assurance (QA) validation within a regulated biopharmaceutical environment.
  • QA release activities within regulated environments.

Preferred Qualifications: Experience in one or more of the following areas:
  • Regulatory audits and inspections.
  • Development, review, and contribution to documentation supporting the testing, validation, and release of Quality Control (QC) and production equipment within clinical and/or commercial GMP environments.
  • Cell and Gene Therapy operations, including clinical and/or commercial-stage environments.
  • Software application deployment, administration, and periodic review within regulated environments.
  • Analytical method validation.

In this role you will:
  • Review and approve asset validation documentation, including User Requirement Specifications (URS), Risk Assessments, Validation Plans, Qualification Protocols, and Validation Reports.
  • Review and approve operational, maintenance, and cleaning (OMC) procedures, ensuring compliance with quality requirements and Good Documentation Practices (GDP).
  • Ensure compliance with applicable regulations and the company's Quality Management System (QMS).
  • Serve as the QA representative for validation deliverables related to GxP-regulated computerized systems, production equipment, laboratory methods, facilities, and IT infrastructure.
  • Provide QA guidance and best practices based on industry standards and current Cell Therapy practices, including Adoptive Cell Therapy.
  • Collaborate with cross-functional stakeholders to align QA Validation activities with U.S. QA Validation Management, Global Quality Operations, and Site Leadership.
  • Provide QA support for Data Management, Digitalization, Artificial Intelligence (AI), Operational Excellence, Business Continuity, and Archival initiatives.

What do we offer?
At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join Immatics
Comprehensive Benefits:
  • Competitive rates for Health, Dental, and Vision Insurance
  • 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
  • 12 company paid holidays
  • 7 days of sick time
  • 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
  • 100% employer-paid short- and long-Term disability coverage
  • 401(k) with immediate eligibility and company match...
  • The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
  • Partially paid parental leave for eligible employees.
  • Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity
We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.
Reasonable Accommodations
We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at RecruitingUS@immatics.com.
Work Authorization
Applicants must be authorized to work in the United States without the need for current or future sponsorship.
Pre-Employment Requirements
Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.

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