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Clinical Research Rn Jobs in Plano, TX (NOW HIRING)

Job Summary As a Research Nurse 1, you'll assist principal investigators with clinical trials ... Registered Nurse (RN) License. * BLS certification within 30 days. Employment Type: FULL_TIME

Active RN or LVN license in the state of Texas * Associate's or Bachelor's degree in Nursing (BSN preferred) * 0-2 years of nursing experience; clinical research experience a plus but not required

Entry Level Research Nurse

Plano, TX ยท On-site

$55 - $75/hr

Active RN or LVN license in the state of Texas * Associate's or Bachelor's degree in Nursing (BSN preferred) * 0-2 years of nursing experience; clinical research experience a plus but not required

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Clinical Research Rn information

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$17

$42

$60

How much do clinical research rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for clinical research rn in Plano, TX is $42.24, according to ZipRecruiter salary data. Most workers in this role earn between $34.76 and $50.14 per hour, depending on experience, location, and employer.

What is a clinical research RN?

Clinical Research Registered Nurses (Clinical Research RNs) are licensed nurses who specialize in conducting and coordinating clinical trials and research studies involving human participants. They collaborate with physicians, researchers, and study coordinators to ensure that research protocols are followed, participants are cared for safely, and all regulatory and ethical guidelines are met. Their duties include administering study medications, collecting data, monitoring patient responses, and educating participants about the study. Clinical Research RNs play a vital role in advancing medical knowledge and improving patient care through research.

How does a clinical research RN typically collaborate with other members of the research team?

A Clinical Research RN works closely with principal investigators, study coordinators, physicians, and data managers to ensure research protocols are followed accurately and patient safety is maintained. They are responsible for communicating patient progress, reporting adverse events, and coordinating care between departments. Regular team meetings and detailed documentation are essential to keep everyone informed and maintain compliance with regulatory standards. This collaborative environment helps ensure research studies run smoothly and efficiently.

What are the key skills and qualifications needed to thrive as a clinical research RN, and why are they important?

To thrive as a Clinical Research RN, you need a solid background in nursing, clinical trial protocols, and regulatory compliance, typically requiring an RN license and experience in research settings. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and Good Clinical Practice (GCP) certification is often expected. Excellent organizational, communication, and critical thinking skills help you coordinate studies, interact with participants, and collaborate with multidisciplinary teams. These competencies ensure the integrity of research data, patient safety, and successful execution of clinical trials.

What is the difference between Clinical Research Rn vs Clinical Research Coordinator?

AspectClinical Research RnClinical Research Coordinator
CredentialsRN license, possibly specialized certificationsTypically bachelor's degree, certifications like CCRP beneficial
Work EnvironmentHospitals, clinics, research institutionsResearch sites, hospitals, clinics
Job FocusPatient care, protocol adherence, data collectionStudy coordination, participant recruitment, data management

While both roles are involved in clinical research, the Clinical Research Rn primarily provides patient care and ensures protocol compliance from a nursing perspective. The Clinical Research Coordinator manages study logistics, participant recruitment, and data collection. Both roles require strong organizational skills, but the RN's focus is more on patient interaction, whereas the Coordinator handles study operations.

How to get into clinical research as a registered nurse?

To become a clinical research RN, obtain a valid nursing license and gain experience in patient care. Additional certifications such as Certified Clinical Research Professional (CCRP) or Good Clinical Practice (GCP) training can improve job prospects, and familiarity with research protocols and data management is beneficial.

What do clinical research RNs do in clinical research?

Clinical research RNs coordinate and monitor clinical trials by recruiting participants, collecting data, administering treatments, and ensuring compliance with study protocols and regulations. They often work closely with investigators, maintain accurate documentation, and may require certification such as CCRP. Their role is essential for the safe and effective conduct of research studies.

What cities near Plano, TX are hiring for Clinical Research Rn jobs?

Cities near Plano, TX with the most Clinical Research Rn job openings:

Infographic showing various Clinical Research Rn job openings in Plano, TX as of August 2026, with employment types broken down into 2% As Needed, 80% Full Time, 12% Part Time, and 6% Contract. Highlights an 85% Physical, 1% Hybrid, and 14% Remote job distribution, with an average salary of $88,234 per year, or $42.4 per hour.

Full-time

Posted 9 days ago


Key responsibilities

  • Perform protocol-specific clinical procedures such as PIV line placement, blood draws, infusions, injections, and specimen collection.

  • Oversee day-to-day study operations across multiple sites, ensuring protocol implementation and quality standards.

  • Supervise and train research personnel, delegate responsibilities, and monitor performance to ensure compliance and efficiency.


Job description

Position Summary

The Clinical Research Nurse (RN) provides clinical, administrative, and operational leadership for clinical trials conducted in outpatient clinic and hospital settings. This role is responsible for performing protocol-required clinical procedures, overseeing multi-site study execution, ensuring regulatory compliance, and supervising research personnel. The Clinical Research Nurse plays a critical role in maintaining study integrity, participant safety, regulatory compliance, and operational efficiency while providing care to pediatric and adult populations, including individuals with developmental disabilities.

Primary Responsibilities

Clinical Trial Implementation

  • Perform protocol-specific procedures, including peripheral intravenous (PIV) line placement in pediatric and adult participants, infusions, injections, blood draws, venipuncture, specimen collection, and fluid administration.

  • Prepare, handle, and administer investigational products in accordance with protocol and safety standards.

  • Monitor participants for adverse events and ensure appropriate documentation and follow-up.

  • Conduct clinical assessments and support protocol-driven evaluations.

  • Assist physicians and clinical investigators during procedures requiring patient sedation or anesthesia, ensuring patient safety and protocol compliance.

  • Provide nursing care and support for pediatric and adult participants with developmental disabilities, utilizing appropriate communication and behavioral support techniques.

  • Provide participant education and ensure adherence to study requirements.

Administrative & Regulatory Management

  • Maintain essential regulatory documents, study binders, and source documentation.

  • Ensure compliance with Good Clinical Practice (GCP), Institutional Review Board (IRB) requirements, sponsor protocols, and institutional policies.

  • Coordinate study start-up activities, protocol amendments, continuing reviews, and study close-out processes.

  • Maintain investigational product accountability and study supply records.

  • Track enrollment, study milestones, and reporting requirements.

Multi-Site & Operational Oversight

  • Oversee day-to-day study operations across outpatient and hospital-based sites.

  • Ensure consistent protocol implementation and quality standards across locations.

  • Coordinate scheduling, staffing, and resource allocation to meet study timelines.

  • Serve as the primary liaison with investigators, sponsors, CROs, monitors, and institutional departments.

  • Lead preparation for monitoring visits, audits, and inspections.

Personnel Leadership

  • Supervise and mentor research coordinators, nursing staff, and support personnel.

  • Train staff on study protocols, clinical procedures, and compliance standards.

  • Delegate responsibilities and monitor performance and workflow efficiency.

  • Evaluate staff performance and implement process improvements to enhance productivity and compliance.

Qualifications

  • Active, unrestricted Registered Nurse (RN) license required.

  • Bachelor of Science in Nursing (BSN) preferred.

  • Minimum of three (3) years of clinical nursing experience, including infusion therapy, PIV placement, and venipuncture.

  • Demonstrated experience performing blood draws and peripheral intravenous (PIV) line placement in pediatric and adult populations.

  • Experience assisting physicians with procedures involving patient sedation and anesthesia preferred.

  • Experience working with pediatric and adult patients with developmental disabilities preferred.

  • Current Advanced Cardiac Life Support (ACLS) certification required.

  • Current Pediatric Advanced Life Support (PALS) certification preferred.

  • Clinical research experience required.