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Clinical Research Rn Jobs in Missouri (NOW HIRING)

Clinical Research Registered Nurse (RN) Position Summary The Clinical Research RN coordinates and conducts clinical trial activities while ensuring participant safety, protocol compliance, and ...

New

$60K - $99K/yr

This position is in the Pediatric Clinical Research Unit (PCRU), an outpatient research unit ... Current RN licensure in the state of Missouri and/or Illinois, depending on location. * Basic Life ...

$60K - $99K/yr

This position is in the Pediatric Clinical Research Unit (PCRU), an outpatient research unit ... Current RN licensure in the state of Missouri and/or Illinois, depending on location. * Basic Life ...

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Clinical Research Rn information

See Missouri salary details

$17

$41

$59

How much do clinical research rn jobs pay per hour?

As of Aug 23, 2026, the average hourly pay for clinical research rn in Missouri is $41.40, according to ZipRecruiter salary data. Most workers in this role earn between $34.04 and $49.13 per hour, depending on experience, location, and employer.

What is a clinical research RN?

Clinical Research Registered Nurses (Clinical Research RNs) are licensed nurses who specialize in conducting and coordinating clinical trials and research studies involving human participants. They collaborate with physicians, researchers, and study coordinators to ensure that research protocols are followed, participants are cared for safely, and all regulatory and ethical guidelines are met. Their duties include administering study medications, collecting data, monitoring patient responses, and educating participants about the study. Clinical Research RNs play a vital role in advancing medical knowledge and improving patient care through research.

How does a clinical research RN typically collaborate with other members of the research team?

A Clinical Research RN works closely with principal investigators, study coordinators, physicians, and data managers to ensure research protocols are followed accurately and patient safety is maintained. They are responsible for communicating patient progress, reporting adverse events, and coordinating care between departments. Regular team meetings and detailed documentation are essential to keep everyone informed and maintain compliance with regulatory standards. This collaborative environment helps ensure research studies run smoothly and efficiently.

What are the key skills and qualifications needed to thrive as a clinical research RN, and why are they important?

To thrive as a Clinical Research RN, you need a solid background in nursing, clinical trial protocols, and regulatory compliance, typically requiring an RN license and experience in research settings. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and Good Clinical Practice (GCP) certification is often expected. Excellent organizational, communication, and critical thinking skills help you coordinate studies, interact with participants, and collaborate with multidisciplinary teams. These competencies ensure the integrity of research data, patient safety, and successful execution of clinical trials.

What is the difference between Clinical Research Rn vs Clinical Research Coordinator?

AspectClinical Research RnClinical Research Coordinator
CredentialsRN license, possibly specialized certificationsTypically bachelor's degree, certifications like CCRP beneficial
Work EnvironmentHospitals, clinics, research institutionsResearch sites, hospitals, clinics
Job FocusPatient care, protocol adherence, data collectionStudy coordination, participant recruitment, data management

While both roles are involved in clinical research, the Clinical Research Rn primarily provides patient care and ensures protocol compliance from a nursing perspective. The Clinical Research Coordinator manages study logistics, participant recruitment, and data collection. Both roles require strong organizational skills, but the RN's focus is more on patient interaction, whereas the Coordinator handles study operations.

How to get into clinical research as a registered nurse?

To become a clinical research RN, obtain a valid nursing license and gain experience in patient care. Additional certifications such as Certified Clinical Research Professional (CCRP) or Good Clinical Practice (GCP) training can improve job prospects, and familiarity with research protocols and data management is beneficial.

What do clinical research RNs do in clinical research?

Clinical research RNs coordinate and monitor clinical trials by recruiting participants, collecting data, administering treatments, and ensuring compliance with study protocols and regulations. They often work closely with investigators, maintain accurate documentation, and may require certification such as CCRP. Their role is essential for the safe and effective conduct of research studies.

What are popular job titles related to Clinical Research Rn jobs in Missouri?

For Clinical Research Rn jobs in Missouri, the most frequently searched job titles are:

What cities in Missouri are hiring for Clinical Research Rn jobs?

Cities in Missouri with the most Clinical Research Rn job openings:

Infographic showing various Clinical Research Rn job openings in Missouri as of August 2026, with employment types broken down into 79% Full Time, 17% Part Time, and 4% Contract. Highlights an 100% In-person job distribution, with an average salary of $86,106 per year, or $41.4 per hour.

Clinical Research RN in Springfield, MO

Vivian Health

Springfield, MO โ€ข On-site

Other

Medical, Dental, Vision, Retirement, PTO

Posted yesterday

New


Job description

Clinical Research Nurse - Mercy Springfield
Find your calling at Mercy! The Clinical Research Nurse (CRN) is responsible for coordination of research studies conducted by Mercy Research. The Clinical Research Nurse is responsible for the day-to-day operational tasks related to clinical trials and performs a variety of duties including, but not limited to, volunteer recruitment, drug/device/supply inventory maintenance, interaction with physicians, nurses, office staff, patients, and clinical monitors. Duties also include the collection, compilation, documentation and analysis of clinical research data while following local, state and federal regulations. The Clinical Research Nurse will assist in training and preceptor duties. The study load and complexity will increase from the Associate Clinical Research Nurse responsibility, thereby increasing the overall number of enrollments and visits. The Clinical Research Nurse will assist with communication and relationship building with sponsors and CROs.
Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards. Position Details: Clinical Research Registered Nurse (RN) Position Summary

The Clinical Research RN coordinates and conducts clinical trial activities while ensuring participant safety, protocol compliance, and accurate data collection. This role works closely with investigators, sponsors, and study participants to support successful research outcomes.

Key Responsibilities
  • Coordinate clinical research activities and patient visits.
  • Screen, consent, educate, and monitor study participants.
  • Administer investigational products and perform protocol-required procedures.
  • Ensure compliance with study protocols, GCP, and regulatory requirements.
  • Collect, document, and maintain accurate study data and source records.
  • Process laboratory specimens and maintain study supplies.
  • Monitor participant safety and report adverse events as required.
  • Collaborate with investigators, sponsors, CROs, and research staff.
  • Support patient recruitment efforts and community outreach activities.
  • Assist with training and mentoring research team members.
  • Attend study meetings and perform other duties as assigned.
Minimum Qualifications
  • Nursing Diploma, ADN, or BSN.
  • Current RN license in the state of practice.
  • BSN: 2+ years of nursing experience.
  • ADN/Diploma: 3+ years of nursing experience.
  • Experience performing patient assessments, vital signs, ECGs, spirometry, phlebotomy, or willingness to learn.
  • Strong communication, organizational, and problem-solving skills.
  • Proficiency with Microsoft Office and computer applications.
Preferred Qualifications
  • 2+ years of clinical research experience.
  • Phlebotomy experience.
  • Knowledge of clinical trial protocols, GCP, and regulatory requirements.
Key Competencies
  • Clinical judgment
  • Patient-focused care
  • Attention to detail
  • Time management
  • Communication and collaboration
  • Regulatory compliance
  • Critical thinking
Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.