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Clinical R Programmer Jobs in Durham, NC (NOW HIRING)

GSK

Principal Statistical Programmer

Durham, NC · On-site

Expertise in R programming. * 6+ years of clinical programing experience * 5+ years of experience in the Pharmaceutical or Biotechnology industry. * Experience using generative AI tools and coding ...

WiTH Collective

Senior Statistical Programmer (Remote)

Cary, NC · On-site

$104.75 - $128/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

WCG's clinical solutions are built on a foundation of best-in-class clinical services companies. We ... R programming experience highly preferred. * 2 years of macro programming experience required. * At ...

LivaNova

Statistical Programmer II

Raleigh, NC

$90K - $100K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Experience with R, Python, SQL, Git, or other modern programming/version control tools. * Experience with SAS Enterprise Guide or other SAS-based clinical programming environments. * Experience ...

Duke University

Clinical Data Manager

Durham, NC · On-site

  • Medical

  • Dental

  • Retirement

  • PTO

Completion of the DOCR North Carolina state approved Clinical Research Apprenticeship program may ... using R, python, and other programming tools; maintain and curate structured databases and study ...

Duke University

Clinical Data Manager

Durham, NC · On-site

  • Medical

  • Dental

  • Retirement

  • PTO

Completion of the DOCR North Carolina state approved Clinical Research Apprenticeship program may ... using R, python, and other programming tools; maintain and curate structured databases and study ...

IQVIA

Senior Epidemiological Programmer RWE

Durham, NC

$88K - $220K/yr

Demonstrated proficiency in advanced statistical programming using SAS and/or R, macros, SQL ... clinical research services, commercial insights and healthcare intelligence to the life sciences ...

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All JobsClinical R Programmer JobsClinical R Programmer Jobs in Durham, NC

Clinical R Programmer information

See Durham, NC salary details

$23

$62

$99

How much do clinical r programmer jobs pay per hour?

As of Aug 18, 2026, the average hourly pay for clinical r programmer in Durham, NC is $62.59, according to ZipRecruiter salary data. Most workers in this role earn between $51.78 and $70.87 per hour, depending on experience, location, and employer.

What is a Clinical R programmer?

Clinical R Programmers are professionals who use the R programming language to manage, analyze, and visualize clinical trial data in the pharmaceutical, biotech, or healthcare industries. They play a key role in preparing statistical reports, generating tables, listings, and figures (TLFs), and ensuring data integrity for regulatory submissions. Clinical R Programmers collaborate with statisticians, data managers, and clinical teams to ensure the accuracy and compliance of clinical trial results with industry standards and regulatory requirements.

What skills and qualifications are needed to be a Clinical R programmer?

To thrive as a Clinical R Programmer, you need a solid background in statistics, R programming, and clinical trial data analysis, often supported by a degree in statistics, biostatistics, or a related field. Expertise in SAS, CDISC standards (SDTM/ADaM), and familiarity with clinical data management systems are commonly required. Attention to detail, problem-solving skills, and effective communication enable you to interpret data accurately and collaborate with cross-functional teams. These skills are vital for ensuring reliable statistical outputs that support regulatory submissions and data-driven decisions in clinical research.

What are common challenges faced by Clinical R programmers when working with clinical trial data?

Clinical R Programmers often encounter challenges such as handling large and complex datasets, ensuring strict compliance with regulatory standards (like CDISC SDTM and ADaM), and maintaining data integrity throughout the analysis process. Collaboration can be demanding, as programmers must frequently coordinate with biostatisticians, data managers, and clinical teams to interpret data requirements and resolve discrepancies. Staying updated with evolving industry guidelines and managing tight project timelines are also common aspects of the role.

What is the difference between Clinical R Programmer vs Clinical SAS Programmer?

AspectClinical R ProgrammerClinical SAS Programmer
Required CredentialsTypically requires a degree in statistics, biostatistics, or related field; proficiency in R programmingUsually requires a degree in statistics, biostatistics, or related field; proficiency in SAS programming
Work EnvironmentOften works in research-focused settings, academia, or biotech companies using open-source toolsCommonly employed in pharmaceutical companies, CROs, and clinical trial data analysis using SAS
Industry UsageGrowing in popularity for data analysis and visualization in clinical researchStandard in clinical trial data management and regulatory submissions

While both roles involve programming for clinical data analysis, Clinical R Programmers focus on using R for statistical analysis and visualization, whereas Clinical SAS Programmers primarily use SAS for data management and reporting. The choice depends on the company's preferred tools and project requirements.

What are popular job titles related to Clinical R Programmer jobs in Durham, NC?

For Clinical R Programmer jobs in Durham, NC, the most frequently searched job titles are:

What job categories do people searching Clinical R Programmer jobs in Durham, NC look for?

The top searched job categories for Clinical R Programmer jobs in Durham, NC are:

What cities near Durham, NC are hiring for Clinical R Programmer jobs?

Cities near Durham, NC with the most Clinical R Programmer job openings:

Clinical R Programmer jobs near you
Infographic showing various Clinical R Programmer job openings in Durham, NC as of August 2026, with employment types broken down into 2% As Needed, 73% Full Time, 19% Part Time, and 6% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $130,191 per year, or $62.6 per hour.

Statistical Programmer / Clinical Data Architect

Volto USA

Raleigh, NC • On-site

Contractor

Re-posted 16 days ago

Job description

Job Description: Local to Raleigh, NC  Only!
Role Overview
We are seeking a highly experienced Senior Statistical Programmer / Clinical Data Architect with 15+ years of expertise in clinical data programming, CDISC standards, and cloud-based analytics platforms. The ideal candidate will lead end-to-end clinical data workflows, regulatory submissions, and modern data platform transformations in GxP-regulated environments.
This role requires strong domain expertise in SDTM, ADaM, regulatory submissions, and SAS/Python/R programming, combined with experience in cloud platforms (AWS/Azure) and clinical data modernization initiatives.
________________________________________
Key Responsibilities
Clinical Data Programming & Regulatory Submissions
•       Design, develop, and validate SDTM and ADaM datasets in compliance with CDISC standards
•       Lead generation of define.xml, aCRF/eCRF annotations, and submission-ready deliverables
•       Develop and optimize automated submission pipelines for FDA and global regulatory authorities
•       Ensure compliance with GxP, 21 CFR Part 11, HIPAA, and ICH E6 guidelines
Data Engineering & Automation
•       Architect and implement end-to-end clinical data pipelines using SAS, Python, and R
•       Develop reusable SAS macro libraries and automation frameworks
•       Build scalable data pipelines including modern formats (JSON/XPT alternatives)
•       Drive migration from legacy systems to modern data architectures
Cloud & Platform Engineering
•       Lead implementation and optimization of SAS Viya platforms on AWS/Azure
•       Manage cloud infrastructure components (EKS, EC2, EFS, FSx, Databricks, etc.)
•       Implement FinOps practices for cost governance and optimization
•       Evaluate and onboard next-gen analytics platforms (e.g., Databricks)
Leadership & Stakeholder Management
•       Lead cross-functional teams across US, UK, and offshore locations
•       Collaborate with clinical, statistical, regulatory, and IT stakeholders
•       Drive Agile delivery and sprint planning for data and platform initiatives
•       Manage vendor relationships, tool selection, and licensing strategies
Compliance & Governance
•       Ensure adherence to regulatory and audit requirements (FDA, OCC, SOX, Basel III as applicable)
•       Maintain audit-ready documentation and validation processes
•       Implement data governance, traceability, and reproducibility standards
________________________________________
Required Qualifications
•       Bachelor’s or Master’s degree in Computer Science, Statistics, Life Sciences, or related field
•       15+ years of experience in statistical programming and clinical data management
•       Strong expertise in:
o       SAS (Base, Macro, SQL, ODS, STAT, Graph)
o       CDISC standards (SDTM, ADaM, define.xml)
o       Regulatory submissions (FDA, global agencies)
•       Hands-on experience with:
o       Python (Pandas) and/or R (admiral, Shiny)
o       Cloud platforms (AWS/Azure)
•       Strong understanding of GxP and clinical compliance frameworks
________________________________________
Preferred Qualifications
•       Experience with SAS Viya architecture and administration
•       Familiarity with Databricks, DBT, or modern data engineering tools
•       Knowledge of CI/CD tools (Jenkins, Git)
•       Experience in financial/regulatory environments (Basel III, CCAR, OCC) is a plus
•       AWS or cloud certifications
________________________________________
Key Skills
•       Clinical Data Standards: SDTM, ADaM, CDISC
•       Programming: SAS, Python, R, SQL
•       Cloud: AWS, Azure
•       Tools: Pinnacle 21, Git, Jenkins, Power BI, Grafana
•       Methodologies: Agile, DevOps, Data Governance