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The Center for International Blood and Marrow Transplant Research (CIBMTR) and the Division of Hematology and Oncology at the Medical College of Wisconsin (MCW) invite applications for a faculty position as a Senior Scientific Director in the CIBMTR and the Principal Investigator (PI) role in the Stem Cell therapeutic Outcome Database (SCTOD) contract with HRSA. Candidates eligible to be appointed to the rank of Associate Professor or Professor will be considered.

The successful candidate will be expected to devote a minimum of 60-70% of his or her effort to CIBMTR (a percentage of which will be dedicated to the SCTOD role) and may have effort devoted to clinical service in the division of Hematology/Oncology in the adult transplantation and cell therapy unit. In this strategic leadership position, the successful candidate will be fulfilling leadership and PI responsibilities of the SCTOD contract, leading all aspects of this critical CIBMTR function. They will develop a deep understanding of CIBMTR data across the full data pipeline and be involved in innovation and enhancement of data, systems and infrastructure. They will work closely with internal leaders and functional teams; and will develop and strengthen the collaborative relationships with network treatment centers and international partners.

Operate as the lead on the SCTOD contract with HRSA, participating alongside others in the team in all aspects of successfully completing all contract deliverables, including, but not limited to:

Provide scientific leadership to Data Operations staff to ensure and promote data quality, accuracy and appropriateness of data collected to meet the purposes of the SCTOD, and more broadly CIBMTR’s mission

Collaborate with statistical and data operations teams to understand, enhance and perform the annual Center Specific Analysis (CSA) and understand all functions supporting this

Develop a full understanding of data security, and other contract obligations associated with the SCTOD contract

Work closely with the HRSA Project Officer and other team members as well as leads of other awards under the CW Bill Young program

Work closely with MCW, and other appropriate legal and contracting partners to negotiate and fulfill the SCTOD requirements

Collaborate with treatment center directors to ensure US network engagement in, contribution to and innovation around the CSA.

Participate in the strategic mission of data innovation, covering all aspects of the data lifecycle, to enhance the impact and effectiveness of the CIBMTR registry in achieving its mission, broadly supporting the quality and security of CIBMTR data

Lead partnerships with US treatment centers to maximize the strengths of registry data collection and use, while reducing burden

Represent CIBMTR to international registries, influencing the development of globally harmonized clinical definitions, standardized data collection, promoting benchmarking and collaborative research

Collaborate with clinical informatics, disease-specific directors, and CIBMTR leadership to achieve CIBMTR mission

Contribute to CIBMTR and MCW’s strategic goals, funding growth, high impact publications and development of strategic partnerships

The successful candidate may also have a clinical role in the Division of Hematology and Oncology in our internationally recognized cellular therapy clinical program. The clinical responsibilities may include inpatient care for patients undergoing advanced cellular therapies and/or a limited outpatient clinic with a focus on allogeneic transplant MCW’s cellular therapy program serves most of the state of Wisconsin as well as northern Illinois and parts of Michigan. We perform roughly 400 cellular therapy procedures yearly, including autologous and allogeneic transplant, chimeric-antigen T-cell receptor therapy and novel cellular protocols, including cutting edge and first-in-human clinical trials. The physician will be part of a multidisciplinary team and critically involved in the day-to-day management of complex patients. The team includes skilled advanced practice providers, transplant coordinators, nursing staff, pharmacists, and other specialists.

The Division of Hematology and Oncology is a core center member of the Blood and Marrow Transplant Clinical Trials Network (BMT CTN), a lead academic center for the National Clinical Trials Network (NCTN) and an active member of ECOG-ACRIN.

Board certified/board eligible in hematology and/or oncology by the American Board of Internal Medicine

Ability to obtain an unrestricted Wisconsin medical license

Prior experience and training in HCT

Successful candidates will have a strong portfolio of research productivity as evidenced by success a national reputation and high impact publications.

Experience working with the CIBMTR and formal training in research methodology is preferred but not required.

Candidates should have a demonstrated commitment to patient care, clinical excellence and academic collaboration and a strong interest in teaching and clinical research.

CIBMTR is a research collaboration between the NMDP and MCW. CIBMTR collaborates with the global scientific community to advance HCT and cellular therapy research worldwide to increase survival and enrich quality of life for patients. CIBMTR facilitates critical observational and interventional research through scientific and statistical expertise, a large network of transplant centers, a unique and extensive clinical outcomes database and a large repository of donor and recipient biospecimens. Its longitudinal database currently has information for more than 700,000 patients and receives data for an additional 20-25,000 new patients annually. CIBMTR collaborates with the pharmaceutical and biotech industry through a corporate membership and research service fulfillment portfolio. Currently greater than 80 projects are ongoing in collaboration with more than 40 industry teams. Services provided include scientific expertise, data management and statistical support aligned with use of its real-world data registry supporting impactful industry sponsored projects, including the post-approval safety studies (PASS) for CAR-T, gene therapy and other novel interventions.

Scientific oversight of CIBMTR activities is provided by over 15 MD/PhD Scientific Directors who are faculty in the Departments of either Pediatrics, Medicine or Data Science Institute at MCW, as well as 7 MD/PhD-equivalent Scientific Directors on the NMDP CIBMTR campus. Statistical support is provided by 30 MS statisticians over both campuses and 7 additional faculty PhD statisticians at MCW. An additional ~300 staff provide support for all aspects of CIBMTR’s data collection and research activities. Scientific Directors work closely with Operational Directors to provide direction and subject matter expertise. They also work closely with the scientific community, industry, patients, caregivers and other stakeholders to further the mission of the CIBMTR.

MCW is widely respected as an academic center of excellence for the education and training of physicians and scientists, development of graduate and undergraduate medical education programs, basic and translational research, and distinction in multidisciplinary clinical programs. It is ranked as one of the nation’s top 50 academic research institutions. Froedtert Health is a $2B regional health system that delivers world class care in an environment of innovation and discovery. Froedtert Hospital, a 500-bed tertiary care and teaching hospital, has recently been named as one of the top four performing academic medical centers in the nation, winning a Bernard A. Birnbaum, MD, Quality Leadership Award.

MCW provides excellent compensation and a competitive benefits package. We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

The Medical College of Wisconsin (MCW) is the state’s only private medical school and health sciences graduate school. MCW consists of a School of Medicine with campuses in Milwaukee, Green Bay and Central Wisconsin, a School of Graduate Studies, and a School of Pharmacy. MCW is a major national research center ranking in the top third of U.S. medical schools in NIH funding and is the second largest research institution in Wisconsin. Academic medicine is at the core of everything we do at MCW, bringing together scientists, clinicians, students and community members to solve the most complex challenges in health and society. MCW is a diverse group of thought leaders collaborating to pioneer pathways to a healthier world. Every study we conduct and every patient we see leads to new learning and a continuous cycle of life-changing knowledge and innovation.

Approximately 1,780 MCW physicians and approximately 905 advanced practice providers care for more than 484,000 patients of all ages annually at Froedtert Hospital, Zablocki VA Medical Center, Children’s Wisconsin, and many other hospitals and clinics throughout eastern Wisconsin, representing more than 5.1 million patient visits annually.

The beautiful, safe and modern campus of the Milwaukee Regional Medical Center (MRMC) houses Froedtert Hospital, Children’s Wisconsin, Curative Care Network, Versiti Blood Research Institute and the Milwaukee County Behavioral Health Division. These member entities share a common mission of excellence in patient care, medical education, biomedical research and community service.

Commitment to MCW Values

All of our endeavors at MCW, from our internal operations to our interactions with our partners, are driven by our shared organizational values: acting inCaringways – engaging inCollaborativeefforts – approaching our world withCuriosity– advancingInclusivepractices – demonstratingIntegrityin all we do – treating everyone withRespect. We are committed to fostering an inclusive environment that values diversity in backgrounds, experiences and perspectives through merit-based processes, and in alignment with all applicable laws. We believe that embracing human differences is critical to realize our vision of a healthier world, and we recognize that a healthy and thriving community starts from within. Our values define who we are, what we stand for and how we conduct ourselves at MCW. If you believe in embracing individuality and working together according to these principles to improve health for all, then MCW is the place for you.

Milwaukee,the largest city in Wisconsin, is located on Lake Michigan’s western shore. A metropolitan area with more than 1.6 million people, Milwaukee is an affordable, comfortable place to live, work, and play, big enough to be exciting and uncongested enough to get around easily. Milwaukee’s many neighborhoods have incredible charm, accommodating a variety of lifestyles, from high-rise apartments to small farms. Nestled along a magnificent bluff overlooking Lake Michigan, Milwaukee’s downtown is home to botanical gardens, lakefront museums, a theater district, the world champion Milwaukee Bucks, the Milwaukee Brewers, bustling nightlife, and award-winning restaurants. The lake and its harbors are skirted by scenic parklands and provide first-class opportunities for recreation, including hiking, cycling, boating, and more. A recent study ranked Milwaukee as the 15th most walkable of the 50 largest US cities. Milwaukee has all the advantages of a large, vibrant city but without the stress or cost.

The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering an inclusive community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to programs, activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

Dr Bronwen Shaw, Chief Scientific Director CIBMTR MCW beshaw@mcw.edu