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Cell Based Potency Assay Jobs in Delaware (NOW HIRING)

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Microbiology Co-op

Wilmington, DE

Knowledge of or experience with biological models (mammalian cell culture, C. elegans or other). * Knowledge of or experience with bioassays, culture-based or microbial assays, immunoassays, or ...

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Senior Research Scientist

Wilmington, DE

$95K - $121K/yr

Perform transfection of plasmids into mammalian cells, cell line maintenance, generation of ... Collaborate effectively with protein engineers, structural biologists, assay scientists ...

ICON

Senior Research Scientist

Wilmington, DE · On-site

$95K - $121K/yr

Perform transfection of plasmids into mammalian cells, cell line maintenance, generation of ... Collaborate effectively with protein engineers, structural biologists, assay scientists ...

Roquette

Associate Scientist

Wilmington, DE · On-site

$86K - $95K/yr

Using plant-based resources, we collaborate with our customers and partners to imagine and offer ... e.g., cell counting, metabolite analysis, absorbance/fluorescence/luminescence assays, flow ...

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All JobsCell Based Potency Assay JobsCell Based Potency Assay Jobs in Delaware

Cell Based Potency Assay information

What are cell based potency assays?

Cell based potency assays are laboratory tests that use living cells to measure the biological activity of a drug, vaccine, or biologic product. These assays help determine how effective a compound is in producing a desired cellular response, making them crucial for drug development and quality control. By closely mimicking the drug’s mechanism of action in the body, they provide more relevant information about efficacy and safety compared to non-cellular assays.

What are some common challenges faced when developing and validating cell based potency assays in a laboratory setting?

Developing and validating cell-based potency assays can be challenging due to the inherent biological variability of living cells, which can impact assay reproducibility and consistency. Additionally, optimizing assay conditions—such as cell passage number, incubation times, and reagent quality—requires careful attention to detail. Collaboration across multidisciplinary teams, including scientists, quality control, and regulatory affairs, is often necessary to ensure the assay meets rigorous industry and compliance standards. Successful candidates should be comfortable troubleshooting technical issues and adapting protocols to achieve reliable results.

What are the key skills and qualifications needed to thrive as a cell based potency assay scientist, and why are they important?

To excel as a Cell Based Potency Assay Scientist, you need a solid background in cellular biology, assay development, and quantitative analysis, usually supported by a degree in life sciences or a related field. Familiarity with laboratory instruments like flow cytometers, plate readers, and proficiency in data analysis software such as GraphPad Prism are typically required, along with knowledge of GMP/GLP standards. Attention to detail, strong problem-solving abilities, and effective communication skills are essential soft skills in this role. These competencies ensure accurate assay results, regulatory compliance, and clear collaboration with cross-functional teams in biopharmaceutical development.

What is the difference between Cell Based Potency Assay vs Cell Culture Technician?

AspectCell Based Potency AssayCell Culture Technician
Primary ResponsibilitiesAssessing the biological activity of products using cell-based methodsMaintaining and preparing cell cultures for various experiments
Required SkillsKnowledge of assay development, data analysis, cell biology techniquesCell culture techniques, aseptic handling, media preparation
Work EnvironmentLaboratories focused on assay validation and quality controlCell culture labs, manufacturing, or research facilities
Common CertificationsBiotech or laboratory certifications, cell biology trainingCell culture training, laboratory safety certifications

While both roles involve working with cells, the Cell Based Potency Assay specialist focuses on developing and performing assays to measure product activity, whereas the Cell Culture Technician primarily prepares and maintains cell cultures. The assay role requires analytical skills and assay-specific knowledge, while the technician role emphasizes cell handling and maintenance skills.

What are popular job titles related to Cell Based Potency Assay jobs in Delaware?

For Cell Based Potency Assay jobs in Delaware, the most frequently searched job titles are:

What job categories do people searching Cell Based Potency Assay jobs in Delaware look for?

The top searched job categories for Cell Based Potency Assay jobs in Delaware are:

What cities in Delaware are hiring for Cell Based Potency Assay jobs?

Cities in Delaware with the most Cell Based Potency Assay job openings:

Cell Based Potency Assay jobs near you
Infographic showing various Cell Based Potency Assay job openings in Delaware as of September 2026, with employment types broken down into 86% Full Time, and 14% Temporary. Highlights an 100% In-person job distribution.

Research Scientist - Contractor

Wilmington, DE • On-site

Prelude Therapeutics Incorporated
Biotechnology Research and Development • 11 - 50 employees
Learn more about Prelude Therapeutics Incorporatedexternal

Full-time

Re-posted 3 days ago

Job description

Description

Prelude Therapeutics is seeking highly motivated and skilled candidates for a laboratory-based Research Scientist position in their Wilmington, DE location. Prelude is an early-stage biotechnology company founded by proven scientists in cancer drug development. At Prelude Therapeutics, the Research Scientist will play a key role in our mission to design and develop a pipeline of novel therapies for cancer patients, with a focus on small molecule drugs, targeted protein degraders, and conjugates including Degrader-Antibody Conjugates (DACs) and Antibody-Drug Conjugates (ADCs). We are a team of science-driven and passionate scientists committed to innovative and efficient drug discovery activities within a collaborative and dynamic working environment. The successful candidate will be a highly motivated and interactive individual with a background in cell/molecular biology, demonstrating versatility and a willingness to adapt and contribute across various stages of the drug discovery process. Prelude offers a vibrant and collegial work environment and excellent career growth opportunities. Prelude is ideally located within 25 minutes from the Philadelphia International Airport at an emerging research campus at Chestnut Run Innovation & Science Park.

Responsibilities:

  • Evaluate the potency and selectivity of new molecules in various functional and phenotypic cell-based assays.
  • Characterize new molecules through mechanism of action studies.
  • Develop, validate, and optimize assay systems to support the detection of cellular and tissue pharmacodynamic markers.
  • Conduct specific assays related to degraders, DACs, and ADCs, such as antibody internalization, target degradation, and payload release assays.
  • Maintain accurate records of experiments, analyze and interpret results, present summaries, and generate reports of the studies.
  • Contribute to project planning and strategy, ensuring timely progress and troubleshooting of experimental challenges.

Qualifications

Education

  • PhD with 0-3 years of relevant post-doctoral or industry research experience, or MS with 3-6 years of relevant research experience.

Specific Skills (preferred)

  • Hands-on experience with cell/tissue culture, cell viability assays, immunoblotting, quantitative RT-PCR and flow cytometry.
  • Experience with the Incucyte platform for live-cell imaging and analysis.
  • Hands-on experience working with therapeutic      antibodies is preferred, particularly in the context of targeted protein      degraders, Degrader-Antibody Conjugates (DACs), and/or Antibody-Drug Conjugates (ADCs).
  • Proficiency in  data analysis and presentation software.
     

Personal Characteristics

  • Highly self-motivated, with excellent verbal and written communication skills.
  • Ability to work efficiently both independently and in a team/matrix environment.
  • Organized and  detail-oriented, with strong problem-solving skills.

Additional Information

  • This is an on-site position at our Wilmington, DE site. Personal transportation is      necessary to access site.
  • This position  requires 90% wet lab work, focusing on hands-on experimental tasks.

Job Type: Contract - 1 yr

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