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Bioscience Research Jobs in California (NOW HIRING)

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$11

$37

$76

How much do bioscience research jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for bioscience research in California is $37.78, according to ZipRecruiter salary data. Most workers in this role earn between $21.42 and $48.73 per hour, depending on experience, location, and employer.

What is bioscience research?

Bioscience research is the scientific study of living organisms, such as plants, animals, and microorganisms, to understand their structure, function, and interactions. This field covers a wide range of disciplines including biology, biotechnology, genetics, and molecular biology. Researchers in bioscience work to make discoveries that can lead to new medicines, improved agricultural practices, environmental conservation, and advancements in healthcare. Their work often involves laboratory experiments, data analysis, and collaboration with other scientists.

What are some typical challenges faced by professionals in bioscience research, and how can they be addressed?

Professionals in bioscience research often encounter challenges such as designing reproducible experiments, securing funding, and managing large data sets. Collaborating effectively with multidisciplinary teams and staying updated on the latest scientific techniques are also essential. Addressing these challenges typically involves ongoing training, strong project management skills, and proactive communication with colleagues and stakeholders. Building a supportive network within the research community can also help navigate obstacles and foster career growth.

What are the key skills and qualifications needed to thrive in bioscience research, and why are they important?

To thrive in Bioscience Research, you need a solid background in biology or related sciences, analytical thinking, and typically at least a bachelor's or master's degree in a bioscience field. Familiarity with laboratory techniques, data analysis software (such as R or Python), and potentially certifications in laboratory safety are commonly expected. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help researchers excel in collaborative and dynamic environments. These competencies ensure accurate experimentation, reliable data, and productive collaborations, which are essential for advancing scientific discovery.

What is the difference between Bioscience Research vs Laboratory Technician?

AspectBioscience ResearchLaboratory Technician
Required CredentialsBachelor's or higher in biology, biochemistry, or related fields; often requires research experienceAssociate's or bachelor's degree in laboratory sciences; certification may be preferred
Work EnvironmentResearch labs, academic institutions, biotech companiesClinical, industrial, or academic labs; more hands-on testing and sample processing
Employer & Industry UsageUniversities, research institutes, biotech firmsHospitals, diagnostic labs, manufacturing plants

While both roles work within laboratory settings, Bioscience Research focuses on designing and conducting experiments to advance scientific knowledge, often requiring higher education and research skills. Laboratory Technicians perform routine testing and sample analysis, supporting research or clinical operations with more technical, hands-on tasks.

What careers are in bioscience research?

Careers in bioscience research include roles such as research scientist, laboratory technician, biochemist, molecular biologist, and research associate. These positions often require skills in laboratory techniques, data analysis, and knowledge of biological systems, with work typically conducted in labs or research institutions.

What jobs can you do with bioscience research?

Bioscience research skills can lead to roles such as research scientist, laboratory technician, biotechnologist, or clinical research associate. These jobs often require knowledge of laboratory techniques, data analysis, and familiarity with scientific tools and protocols, and may involve working in academic, government, or industry settings.
Bioscience Research jobs near you
Infographic showing various Bioscience Research job openings in California as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, and 3% Contract. Highlights an 78% Physical, 4% Hybrid, and 18% Remote job distribution, with an average salary of $78,585 per year, or $37.8 per hour.

Sr Manager Protein Sciences

South San Francisco, CA • On-site

Twist Bioscience
Biotechnology Research and Development • 1 - 5K employees
Learn more about Twist Bioscienceexternal

$136K - $188K/yr

Full-time

Posted 11 days ago

Key responsibilities

  • Develop small- and medium-scale antibody production workflows, including various formats, culture systems, and purification methods

  • Improve all aspects of the end-to-end antibody development workflow, including construct design, cell line development, cell culture, purification, and analytics

  • Build and manage a team of scientists and research assistants, and independently design, execute, and analyze experiments

Twist Bioscience rating

7.7

Company rating: 7.7 out of 10

Based on 7 frontline employees who took The Breakroom Quiz

Job description

Sr. Manager - Protein Sciences R&D (South San Francisco, CA)Summary

Twist is searching for an RnD scientist/manager with experience in cell biology and protein expression and purification, with an emphasis on antibodies, to lead and enhance our protein sciences capabilities. 

We're looking for a curious, technically deep, and driven scientist who can operate as both a hands-on bench scientist and a builder of people and process. You will start as an individual contributor, personally executing and improving core workflows, while simultaneously defining the technical roadmap, hiring, and building a team around you. As the team grows, you will continue to spend meaningful time at the bench and on experimental design. We are looking for people who have deep technical knowledge and a strong drive to get things done. 

Job title and compensation will be determined based on several factors, including, but not limited to, the candidate's years of experience, skills, knowledge, and abilities.

Key Responsibilities:
  • Develop small- and medium-scale antibody production workflows, including various formats (single-chain, IgG, multi-specific), culture systems, and purification methods
  • Improve all aspects of the end-to-end antibody development workflow: construct design, cell line development, cell culture, purification, and analytics
  • Build from the ground up and manage a team of scientists and RAs that will aid you in your work 
  • Independently design and execute experiments, and analyze experimental data
  • Move projects forward efficiently / manage time and resources effectively / prioritize tasks in accordance with the company's goals
  • Document and communicate results clearly and succinctly
  • Be helpful/collaborative/proactive
  • Stay up to date with new developments, companies, and technologies
  • Be the ultimate subject matter expert, and understand all aspects of your work as profoundly as possible, including details that are adjacent to your projects
What You'll Bring to the Team:
  • Deep hands-on experience designing, expressing, and optimizing monoclonal antibodies, with demonstrated understanding of Fc structure-function relationships (effector function, stability, manufacturability).
  • Proven experience with bispecific antibody architectures, including but not limited to:
    • Knob-in-hole, CrossMab, common light chain, or similar
    • Chain pairing control and mispairing mitigation
  • Experience generating and optimizing stable mammalian cell lines (CHO preferred):
    • Vector design, promoter/selection strategies
    • Clone screening, productivity optimization, and stability assessment
  • Strong understanding of transient vs stable expression tradeoffs and when to deploy each during platform development.
  • Experience improving expression yields and product quality through sequence, vector, and host engineering.
  • Demonstrated ability to build, improve, and standardize antibody generation workflows, not just execute existing SOPs.
  • Experience developing high-throughput or semi-automated workflows for expression, purification, and screening.
  • Strong understanding of platform robustness, reproducibility, and cost drivers.
  • Hands-on experience with antibody characterization methods, such as:
    • SEC, CE-SDS
    • Binding kinetics (BLI or SPR)
    • Basic biophysical profiling (DSF, DLS)
  • Strong mechanistic understanding of antibody biology, structure, and expression bottlenecks
  • Experience designing platforms that support multiple antibody modalities (mAbs, bispecifics, Fc-engineered variants)
  • A track record of successful and creative method development
 Qualifications:
  • PhD in Cell Biology, Biochemistry, or a closely related field
  • 5+ years of experience in protein sciences 
  • 5 years of management experience
  • Hands-on experience working with antibody expression and purification
  • Experience with liquid-handling systems and automation is a plus
  • Familiarity with Python or equivalent programming languages is a plus
About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as "writing" DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

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