The role partners closely with Discovery, Bioinformatics, Biomarker, Clinical, and other development functions to ensure mechanistic hypotheses and patient-relevant data are fully integrated into ...
The role partners closely with Discovery, Bioinformatics, Biomarker, Clinical, and other development functions to ensure mechanistic hypotheses and patient-relevant data are fully integrated into ...
... bioinformatics. • Demonstrate ability to work in a highly collaborative team environment. • Experience leading a diverse scientific team. • Experience managing a scientific group Disclaimer:
... bioinformatics. • Demonstrate ability to work in a highly collaborative team environment. • Experience leading a diverse scientific team. • Experience managing a scientific group Disclaimer:
Strong background in healthcare-related fields such as medicine, pharma, bioinformatics, or biostatistics is highly beneficial. * A PhD in a relevant field is preferred but not required if ...
Strong background in healthcare-related fields such as medicine, pharma, bioinformatics, or biostatistics is highly beneficial. * A PhD in a relevant field is preferred but not required if ...
Strong background in healthcare-related fields such as medicine, pharma, bioinformatics, or biostatistics is highly beneficial. * A PhD in a relevant field is preferred but not required if ...
Strong background in healthcare-related fields such as medicine, pharma, bioinformatics, or biostatistics is highly beneficial. * A PhD in a relevant field is preferred but not required if ...
Open Rank Professor (Tenure-Track/Tenured) in Biomedical Engineering Quantitative Systems Pharmacolo
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Tenure-Track/Tenured) in Biomedical Engineering Quantitative Systems Pharmacolo
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Tenure-Track/Tenured) in Biomedical Engineering Quantitative Systems Pharmac...
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Tenure-Track/Tenured) in Biomedical Engineering Quantitative Systems Pharmac...
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Continuing Track) Biomedical Engineering Quantitative Systems Pharmacology
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Continuing Track) Biomedical Engineering Quantitative Systems Pharmacology
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Continuing Track) Biomedical Engineering Quantitative Systems Pharmacology
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Open Rank Professor (Continuing Track) Biomedical Engineering Quantitative Systems Pharmacology
Newark, DE · On-site
... bioinformatics, and proteomics cores), Nanofabrication (cleanroom, materials characterization, and advanced microscopy), and core labs for human-based studies. Access to active outpatient clinics is ...
Bioinformatics Job information
What are some common challenges faced by professionals in bioinformatics roles, and how can they be addressed?
Bioinformatics professionals often encounter challenges such as managing large and complex datasets, keeping up with rapidly evolving technologies, and collaborating effectively with interdisciplinary teams. To address these challenges, it's important to develop strong data management and analytical skills, stay updated through continuous learning, and communicate clearly with both biologists and computer scientists. Leveraging version control tools, computational resources, and participating in collaborative projects can also help streamline workflows and enhance productivity.
What are the key skills and qualifications needed to thrive as a Bioinformatics professional, and why are they important?
To thrive in a Bioinformatics job, you need a strong background in biology, statistics, and computer science, often supported by a degree in bioinformatics or a related field. Familiarity with programming languages (such as Python, R, or Perl), bioinformatics databases, and tools like BLAST or Next-Generation Sequencing platforms is essential. Strong analytical thinking, attention to detail, and effective communication skills set outstanding professionals apart in this role. These skills are crucial for accurately interpreting complex data, collaborating with interdisciplinary teams, and advancing research outcomes.
What are bioinformatics jobs?
Bioinformatics jobs involve the application of computer science, mathematics, and biology to analyze and interpret complex biological data, such as genetic sequences. Professionals in this field develop algorithms, create databases, and use statistical tools to solve problems in genomics, drug discovery, and other life sciences. These roles are typically found in research institutions, biotechnology companies, pharmaceutical firms, and academic settings. The field is growing rapidly due to advances in technology and the increasing importance of big data in biology.
What are popular job titles related to Bioinformatics Job jobs in Delaware? For Bioinformatics Job jobs in Delaware, the most frequently searched job titles are:
What job categories do people searching Bioinformatics Job jobs in Delaware look for? The top searched job categories for Bioinformatics Job jobs in Delaware are:
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Principal Investigator, Translational Biomarker Discovery Laboratory
Wilmington, DE • On-site
Full-time
Posted 4 days ago
Job description
Overview
A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
Job Summary (Primary function)
The Associate Director, Translational Sciences is a senior, lab-embedded translational scientist who leads the design and execution of strategies that bridge preclinical discovery and early clinical development. This role is responsible for converting patient-derived, multi-omic data generated internally and through external collaborations into actionable assays, biomarkers, and translational insights that support therapeutic target discovery, preclinical de-risking, and dose prediction and optimization.
The Associate Director provides scientific and technical leadership by integrating multi-omic analyses (e.g., transcriptomic, proteomic, and cellular profiling) with advanced assay development to define mechanism-aligned biomarkers and pharmacodynamic readouts that inform target selection, exposure-response understanding, and early clinical strategy. The role partners closely with Discovery, Bioinformatics, Biomarker, Clinical, and other development functions to ensure mechanistic hypotheses and patient-relevant data are fully integrated into program decisions.
This position is intentionally designed as a scientist-first role, emphasizing hands-on laboratory engagement, technology implementation, and data interpretation. The Principal Investigator/Associate Director will primarily operate as a senior individual contributor, with the potential to oversee a small team of laboratory scientists or matrixed contributors over time, while remaining actively involved in experimental design, assay execution, and cross-functional program support.
Essential Functions of the Job (Key responsibilities)
• Lead the design, development, and implementation of state-of-the-art translational assays and platforms, including molecular, cellular, and multi-omic technologies.
• Drive biomarker discovery and validation from exploratory research through fit-for-purpose assay development for preclinical and early clinical use.
• Apply advanced technologies (e.g., transcriptomics, proteomics, spatial biology, and single-cell approaches) to address key translational and mechanistic questions.
• Integrate patient-derived multi-omic datasets to support therapeutic target discovery, prioritization, and validation across oncology and inflammation/autoimmune programs.
• Collaborate with bioinformatics and data science partners to translate complex multi-omic data into biologically and translationally actionable insights.
• Provide translational input to preclinical development programs, including mechanism-of-action confirmation, exposure-response evaluation, and dose optimization strategy.
• Contribute to early toxicology assessment and de-risking, including identification of safety-relevant biomarkers and translational readouts.
• Design and utilize in vivo, ex vivo, and human-relevant model systems, including patient-derived samples, organoids, primary cells, and PBMC-based platforms.
• Ensure scientific rigor, reproducibility, and high-quality data interpretation across all assays and experimental approaches.
• Provide technical leadership and mentorship within the Translational Biomarker Discovery Lab, including hands-on experimental guidance and oversight of external collaborations or CROs as needed.
Qualifications (Minimal acceptable level of education, work experience, and competency)
• PhD with post doc (or equivalent) in Oncology, Molecular Biology, Systems Biology, Immunology, or a related life sciences discipline
• 3-10 years of experience in translational research within pharma, biotech, or a comparable research environment
• Strong, demonstrable expertise in assay development, optimization, and implementation
• Hands on experience with advanced molecular and cellular technologies and multi omic platforms
• Proven ability to integrate biological data across multiple modalities to inform discovery and translational decisions
• Experience working with human samples and clinically relevant model systems
• Strong scientific communication skills and ability to collaborate effectively in matrixed teams
Preferred
• Experience supporting biomarker strategies for early clinical programs
• Familiarity with oncology and/or inflammatory/autoimmune disease biology
• Experience interacting with toxicology, DMB, or CQP functions
• Comfort working in a role that combines scientific independence with focused team oversight, rather than large scale management
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
We Respect Your Privacy
Learn more at: http://www.incyte.com/privacy-policy
The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here.
You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.
You can learn more about Incyte's data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable).
Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.
A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
Job Summary (Primary function)
The Associate Director, Translational Sciences is a senior, lab-embedded translational scientist who leads the design and execution of strategies that bridge preclinical discovery and early clinical development. This role is responsible for converting patient-derived, multi-omic data generated internally and through external collaborations into actionable assays, biomarkers, and translational insights that support therapeutic target discovery, preclinical de-risking, and dose prediction and optimization.
The Associate Director provides scientific and technical leadership by integrating multi-omic analyses (e.g., transcriptomic, proteomic, and cellular profiling) with advanced assay development to define mechanism-aligned biomarkers and pharmacodynamic readouts that inform target selection, exposure-response understanding, and early clinical strategy. The role partners closely with Discovery, Bioinformatics, Biomarker, Clinical, and other development functions to ensure mechanistic hypotheses and patient-relevant data are fully integrated into program decisions.
This position is intentionally designed as a scientist-first role, emphasizing hands-on laboratory engagement, technology implementation, and data interpretation. The Principal Investigator/Associate Director will primarily operate as a senior individual contributor, with the potential to oversee a small team of laboratory scientists or matrixed contributors over time, while remaining actively involved in experimental design, assay execution, and cross-functional program support.
Essential Functions of the Job (Key responsibilities)
• Lead the design, development, and implementation of state-of-the-art translational assays and platforms, including molecular, cellular, and multi-omic technologies.
• Drive biomarker discovery and validation from exploratory research through fit-for-purpose assay development for preclinical and early clinical use.
• Apply advanced technologies (e.g., transcriptomics, proteomics, spatial biology, and single-cell approaches) to address key translational and mechanistic questions.
• Integrate patient-derived multi-omic datasets to support therapeutic target discovery, prioritization, and validation across oncology and inflammation/autoimmune programs.
• Collaborate with bioinformatics and data science partners to translate complex multi-omic data into biologically and translationally actionable insights.
• Provide translational input to preclinical development programs, including mechanism-of-action confirmation, exposure-response evaluation, and dose optimization strategy.
• Contribute to early toxicology assessment and de-risking, including identification of safety-relevant biomarkers and translational readouts.
• Design and utilize in vivo, ex vivo, and human-relevant model systems, including patient-derived samples, organoids, primary cells, and PBMC-based platforms.
• Ensure scientific rigor, reproducibility, and high-quality data interpretation across all assays and experimental approaches.
• Provide technical leadership and mentorship within the Translational Biomarker Discovery Lab, including hands-on experimental guidance and oversight of external collaborations or CROs as needed.
Qualifications (Minimal acceptable level of education, work experience, and competency)
• PhD with post doc (or equivalent) in Oncology, Molecular Biology, Systems Biology, Immunology, or a related life sciences discipline
• 3-10 years of experience in translational research within pharma, biotech, or a comparable research environment
• Strong, demonstrable expertise in assay development, optimization, and implementation
• Hands on experience with advanced molecular and cellular technologies and multi omic platforms
• Proven ability to integrate biological data across multiple modalities to inform discovery and translational decisions
• Experience working with human samples and clinically relevant model systems
• Strong scientific communication skills and ability to collaborate effectively in matrixed teams
Preferred
• Experience supporting biomarker strategies for early clinical programs
• Familiarity with oncology and/or inflammatory/autoimmune disease biology
• Experience interacting with toxicology, DMB, or CQP functions
• Comfort working in a role that combines scientific independence with focused team oversight, rather than large scale management
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
We Respect Your Privacy
Learn more at: http://www.incyte.com/privacy-policy
The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here.
You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.
You can learn more about Incyte's data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable).
Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.
About Incyte
Sourced by ZipRecruiter
Industry
Pharmaceutical and medicine manufacturing
Company size
501 - 1,000 Employees
Headquarters location
Wilmington, DE, US
Year founded
1991