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Bioinformatics Job Jobs in Connecticut (NOW HIRING)

Strong Scientific understanding and experience in Bioinformatics * Experience in Pharmaceutical research a plus * The successful candidate will have experience with more than one of the following ...

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Bioinformatics Job information

What are some common challenges faced by professionals in bioinformatics roles, and how can they be addressed?

Bioinformatics professionals often encounter challenges such as managing large and complex datasets, keeping up with rapidly evolving technologies, and collaborating effectively with interdisciplinary teams. To address these challenges, it's important to develop strong data management and analytical skills, stay updated through continuous learning, and communicate clearly with both biologists and computer scientists. Leveraging version control tools, computational resources, and participating in collaborative projects can also help streamline workflows and enhance productivity.

What are the key skills and qualifications needed to thrive as a bioinformatics professional?

To thrive in a Bioinformatics job, you need a strong background in biology, statistics, and computer science, often supported by a degree in bioinformatics or a related field. Familiarity with programming languages (such as Python, R, or Perl), bioinformatics databases, and tools like BLAST or Next-Generation Sequencing platforms is essential. Strong analytical thinking, attention to detail, and effective communication skills set outstanding professionals apart in this role. These skills are crucial for accurately interpreting complex data, collaborating with interdisciplinary teams, and advancing research outcomes.

What is a bioinformatics job?

Bioinformatics jobs involve the application of computer science, mathematics, and biology to analyze and interpret complex biological data, such as genetic sequences. Professionals in this field develop algorithms, create databases, and use statistical tools to solve problems in genomics, drug discovery, and other life sciences. These roles are typically found in research institutions, biotechnology companies, pharmaceutical firms, and academic settings. The field is growing rapidly due to advances in technology and the increasing importance of big data in biology.
Infographic showing various Bioinformatics Job job openings in Connecticut as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 21% Part Time, 3% Temporary, and 6% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution.

Software Engineer II - Bioinformatics R&D - Remote

SEMA4

Stamford, CT • On-site, Remote

Full-time

Re-posted 2 days ago


Job description

Sema4 is a patient-centered health intelligence company dedicated to advancing healthcare through data-driven insights. Sema4 is transforming healthcare by applying AI and machine learning to multidimensional, longitudinal clinical and genomic data to build dynamic models of human health and defining optimal, individualized health trajectories. Centrellis®, our innovative health intelligence platform, is enabling us to generate a more complete understanding of disease and wellness and to provide science-driven solutions to the most pressing medical needs. Sema4 believes that patients should be treated as partners, and that data should be shared for the benefit of all.
Sema4 is seeking a talented, self-motivated Software Engineer II - Bioinformatics R&D to contribute to cutting-edge translational bioinformatics and clinical product development. As a member of the R&D Bioinformatics department, you will act as a critical member of the Sema4 clinical and research ecosystem focused on innovation, reliability, and quality analysis of high-throughput data at an unprecedented scale. You will use advanced cloud computing technologies to do big data analytics. You will be part of an interdisciplinary team that develops computational methods and pipelines to interpret large-scale human genome and transcriptome sequencing data to understand mutations and mutation processes in cancer and reproductive health and to translate that understanding to clinical utility. You will develop systems for integrating novel informatics and genomics tools and methodologies into clinical products and practices.
RESPONSIBILITIES
  • Carry out software design, coding, testing, debugging, and documentation
  • Automate existing analysis workflows, migrate existing workflows to cloud platforms, and develop new workflows and pipelines for clinical and research projects
  • Develop, implement, and follow best practices in software development, code versioning, software testing, and deployment
  • Collaborate closely with scientists, clinicians, and product managers to design, engineer, and implement analytics pipeline solutions in the Amazon AWS cloud environment
  • Deliver high-quality, well-tested software to the production bioinformatics team for use in clinical products
  • Contribute to bioinformatics research analysis
  • Communicate effectively with collaborators (computational and bioinformatics scientists on R&D and production teams, IT/HPC, clinical lab directors, knowledgebase and curation teams, wet lab staff) to understand and satisfy product and research analysis needs
  • Train and provide support for bioinformatics scientists and other team members in internally developed best practices for software development, testing, and software development lifecycle (SDLC) policies

QUALIFICATIONS
  • M.S. in Computer Science, Computer Engineering, Bioinformatics, Computational Biology, or related fields. B.S. plus equivalent experience will be considered
  • 2+ years of post-graduate software development experience
  • Working in a team, self-motivation, ability to manage multiple tasks simultaneously, ability to solve problems independently
  • Possess strong understanding of computer science fundamentals, algorithms, and software engineering best practices
  • Strong coding proficiency in Python and R programming languages or similar. Experience with multiple coding languages such as Java/Scala is preferred.
  • Programming experience in Unix/Linux environment
  • Experience with Docker or similar software container platform
  • Hands-on experience working with NGS and bioinformatics tools will be a plus, especially GATK and WDL and common NGS data formats (VCF, BAM)
  • Experience working with cloud computing infrastructures will be a plus, especially on Amazon AWS and DNAnexus
  • Developing codebases using distributed version control tools (especially Git) and software issue tracking systems (especially Jira)
  • Excellent communication and interpersonal skills needed for working in an interdisciplinary team of scientists, engineers, and clinicians
  • Well-versed in the art of effective technical communication, especially graphical communication, about systems design and high-complexity datasets