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Bioinformatics Engineering Jobs in Raleigh, NC (NOW HIRING)

Postdoctoral

Chapel Hill, NC

$41K - $56K/yr

The ideal candidate will have significant expertise in bioinformatics and cheminformatics, working knowledge of multivariate statistical and data mining techniques, and strong programming skills.

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Data Engineer

Durham, NC · On-site

$57 - $63/hr

Bachelor's degree in Computer Science, Data Engineering, Data Science, Bioinformatics, Statistics, Environmental Science, or a related field. * Minimum of three (3) years of professional experience ...

Master's degree in Computer Science, Statistics, Biostatistics, Bioinformatics, Computational Biology, or a related quantitative field. * Strong programming skills. * Experience with machine learning ...

Master's degree in Computer Science, Statistics, Biostatistics, Bioinformatics, Computational Biology, or a related quantitative field. * Strong programming skills. * Experience with machine learning ...

Temporary Technology Support Technician

Raleigh, NC · On-site

$32K - $41K/yr

... bioinformatic analyses, oversee XML and Python program development, deploy AI solutions to ... The position will require the technician to provide training and programming support to students ...

Associate Data Scientist

Durham, NC · Hybrid

$57K - $57K/yr

... Bioinformatics, Information Systems or Information Technology. * 6 months or more experience (academic, internship, or professional) programming in Python, R, or SQL * 6 months or more experience ...

New

Associate Data Scientist

Durham, NC · On-site

$57K - $57K/yr

... Bioinformatics, Information Systems or Information Technology. * 6 months or more experience (academic, internship, or professional) programming in Python, R, or SQL * 6 months or more experience ...

The Department of Biostatistics & Bioinformatics (B&B) at the Duke University School of Medicine ... Strong programming in R and/or Python; best practices in reproducible research * Excellent ...

The Department of Biostatistics & Bioinformatics (B&B) at the Duke University School of Medicine ... Strong programming in R and/or Python; best practices in reproducible research * Excellent ...

... Engineering, and Pathology. The Ostrom lab is focused on understanding genetic and other factors ... D. in computational biology, bioinformatics, computer science, statistics, genetic epidemiology, or ...

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Showing results 1-20

Bioinformatics Engineering information

See Raleigh, NC salary details

$41.8K

$127.4K

$231.8K

How much do bioinformatics engineering jobs pay per year?

As of Jun 28, 2026, the average yearly pay for bioinformatics engineering in Raleigh, NC is $127,394.00, according to ZipRecruiter salary data. Most workers in this role earn between $93,300.00 and $152,600.00 per year, depending on experience, location, and employer.

What is the difference between Bioinformatics Engineering vs Bioinformatics Analyst?

AspectBioinformatics EngineeringBioinformatics Analyst
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related fields; programming skillsBachelor's or Master's in Bioinformatics, Biology, or related fields; data analysis skills
Work EnvironmentResearch labs, biotech companies, healthcare institutionsResearch institutions, healthcare, pharmaceutical companies
Employer & Industry UsageDevelops tools, pipelines, and software for data analysisInterprets data, generates reports, supports research projects

Bioinformatics Engineering focuses on developing software and pipelines for data processing, requiring programming expertise. In contrast, Bioinformatics Analysts primarily interpret data and generate insights, often with a stronger emphasis on biological knowledge. Both roles are vital in biotech and healthcare industries, but they differ in technical scope and daily tasks.

What is a bioinformatics engineer?

A bioinformatics engineer is a professional who develops and applies computational tools and techniques to analyze and interpret biological data, such as DNA sequences or protein structures. They combine expertise in computer science, biology, and mathematics to create software, manage databases, and solve complex biological problems. Bioinformatics engineers often work in research, pharmaceuticals, healthcare, and biotechnology industries to help advance scientific discoveries and medical innovations.

What engineers make $500,000?

Senior bioinformatics engineers with extensive experience, advanced skills in programming, data analysis, and familiarity with tools like Python, R, and cloud platforms can reach salaries of $500,000 or more, especially in high-demand industries or leadership roles. Achieving this level often requires a combination of technical expertise, industry experience, and sometimes managerial responsibilities.

How do bioinformatics engineers typically collaborate with biologists and data scientists in a research setting?

Bioinformatics engineers frequently work in cross-disciplinary teams, partnering closely with biologists to understand experimental goals and with data scientists to analyze complex datasets. Effective communication is key, as engineers must translate biological questions into computational workflows and interpret results in a way that is meaningful to non-technical team members. This collaborative approach not only accelerates research but also helps engineers gain a deeper understanding of biological processes, which can lead to more innovative solutions and professional growth.

How much does a bioinformatics engineer make?

The average salary for a bioinformatics engineer typically ranges from $70,000 to $120,000 annually, depending on experience, education, and location. Professionals with advanced skills in programming, data analysis, and familiarity with tools like Python, R, and Linux tend to earn higher salaries.

What are the key skills and qualifications needed to thrive as a Bioinformatics Engineer, and why are they important?

To thrive as a Bioinformatics Engineer, you need a solid background in biology, computer science, and statistics, often supported by a degree in bioinformatics or a related field. Familiarity with programming languages like Python or R, experience with bioinformatics tools (e.g., BLAST, GATK), and proficiency with databases and cloud computing platforms are typically required. Strong problem-solving, analytical thinking, and collaboration skills set standout professionals apart in this interdisciplinary field. These competencies are crucial for effectively analyzing complex biological data and driving innovation in life sciences research.

What do bioinformatics engineers do?

Bioinformatics engineers develop and implement computational tools and algorithms to analyze biological data, such as genetic sequences and molecular structures. They often work with programming languages like Python or R, utilize databases, and collaborate with biologists to interpret data for research and medical applications.

What engineers make $300,000 a year?

Senior bioinformatics engineers with extensive experience, advanced skills in programming, data analysis, and familiarity with tools like Python, R, and cloud platforms can earn $300,000 or more annually, especially in high-demand biotech or pharmaceutical industries. Achieving this level often requires advanced degrees, certifications, and leadership responsibilities.
What cities near Raleigh, NC are hiring for Bioinformatics Engineering jobs? Cities near Raleigh, NC with the most Bioinformatics Engineering job openings:
Principal Software Engineer - Variant Knowledge Platform

Principal Software Engineer - Variant Knowledge Platform

Labcorp

Durham, NC • On-site

$130K - $174K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 3 days ago


Labcorp rating

6.6

Company rating: 6.6 out of 10

Based on 1,105 frontline employees who took The Breakroom Quiz

78th of 103 rated laboratories


Job description

Labcorp is a leader in diagnostics, drug development and healthcare innovation. Across every role, we harness data and AI to work smarter, move faster and create breakthrough solutions that improve health outcomes for people. With our global scale and deep expertise, you'll do meaningful work, grow your career and make a real impact. Together, we're improving health and improving lives.
Labcorp is a global leader in diagnostic testing and drug development solutions, helping healthcare providers, researchers, and patients make informed decisions that advance care. Join us in our mission to improve health and improve lives.
Work Schedule
This is a full-time, exempt (salaried) position assigned to a First Shift schedule, with standard business hours of Monday through Friday, 8:00 a.m. to 5:00 p.m. in your time zone. Business needs may occasionally require flexibility in work hours, including earlier, later, or additional hours, with reasonable notice provided when possible.
Responsibilities
  • Own the technical design for large, ambiguous, open-ended problems that span the Variant Knowledge Platform and the broader interpretation stack, where there is no clear off-the-shelf solution.
  • Define and evolve the data models for variant identity, classification, and annotation, holding a high bar for correctness and consistency. Identity or schema drift in this domain can corrupt classifications platform-wide.
  • Design production-grade, versioned REST API contracts, secured via the platform's identity provider (Okta), that internal consumers and enterprise clients integrate against, including versioning, deprecation, and governance strategies.
  • Lead the evolution of the systems that turn raw bioinformatic data into trustworthy variant- and sample-level information, and the pipelines that source, maintain, and serve variant annotations, toward real-time, multi-tenant operation.
  • Drive the architecture for automating evidence placement and classification, and for scaling the storage and retrieval of sample- and variant-level data as volume and client count grow.
  • Define org-wide system architectures and rally engineers and stakeholders around them through clear rational, written design documents, and Architecture Decision Records (ADRs).
  • Lead cross-team technical programs as a named principal-level lead, coordinating design, sequencing, and delivery across platform, boundary/tenancy, and curation teams, and represent the platform in the Architecture Review Forum.
  • Set the strategy for system operability: testing, observability (including multi-tenant observability), health monitoring, reliability, and on-call practices under a "you build it, you run it" model.
  • Lead large-scale data migration and backfill efforts, such as consolidating legacy interpretation data into VKB, with the rigor, staging, and validation gates such work demands.
  • Shape the platform's role in enabling future test content and assay development through its data and services.
  • Mentor and level up engineers across multiple teams through technical guidance, design review, and role-modeling, multiplying the org's overall engineering capability.
  • Partner with cross-functional stakeholders across product, curation science, and clinical to identify business opportunities enabled by the platform and align technical strategy to them.
  • Communicate technical vision and trade-offs clearly to audiences ranging from individual engineers to executives, securing buy-in for direction-setting decisions.

Minimum Qualifications
  • Bachelor's Degree.
  • Five or more years of experience in REST API and contract design, including versioning and depreciation strategy and secure service-to-service authentication (e.g., Okta-based identity).
  • Two or more years of experience designing and operating cloud-based services on AWS.
  • Five or more years of experience in a primary backend programming language used for data-intensive services (e.g., Python).

Preferred Qualifications
  • One or more years of experience in genomics or bioinformatics, such as variant interpretation, clinical genetics, HGVS/variant nomenclature, gene/transcript annotation, or evidence-based classification.
  • Two or more years of experience with event-driven and asynchronous messaging architectures (e.g., AWS SQS) and building clean REST gateways in front of them.
  • One or more years of experience working in a regulated or clinical environment, including version pinning and validation needs driven by regulatory requirements.

Additional Qualifications
  • Experience building multi-tenant, platform-as-a-product systems serving multiple internal and external consumers.
  • Experience delivering multi-tenant observability and cross-cutting reliability for shared platform services.
  • Experience executing large one-time data migrations and backfills with provenance and validation guarantees.
  • Experience designing, building, and operating large-scale, distributed backend systems and data platforms in production.
  • Experience defining and driving operational excellence across testing strategy, observability, health monitoring, and production reliability.
  • Strong data modeling skills for systems where data consistency and correctness are critical, including schema evolution and migration at scale.
  • Experience of org-wide technical leadership: setting architecture across teams, authoring ADRs or equivalent design records, and building alignment across engineering and cross-functional partners on ambiguous, high-impact initiatives.
  • Excellent written and verbal communication, including the ability to tailor technical messaging from engineers to executive audiences.
  • Familiarity with analytics data ecosystems (e.g., Snowflake) and the trade-offs between batch or lagged and real-time data paths.

Labcorp Genetics is seeking a Principal Software Engineer to help shape and build the Variant Knowledge Platform, the team and systems responsible for variant identity, classification, and annotation. The platform provides the authoritative source of variant truth that powers clinical interpretation, curation, and analytics across the organization.
In this role you will own ambiguous, org-spanning technical problems end to end, define the architectures and API contracts that platform consumers build on, drive cross-team initiatives, and raise the engineering bar for teams well beyond your own. Because variant identity and classification data flow directly into clinical reports and downstream analytics, the systems you design must be correct, versioned, and durable.
Application Window closes 8/7/2026
Pay Range: $180,000 - $205,000 annually
All job offers will be based on a candidate's skills and prior relevant experience, applicable degrees / certifications, as well as internal equity and market data. The position is also eligible for an annual bonus under the Labcorp Bonus Plan. Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.
Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan. Employees who are regularly scheduled to work a 7 on 7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information, please click here.
Labcorp is proud to be an Equal Opportunity Employer:
Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.
We encourage all to apply
If you are an individual with a disability who needs assistance using our online tools to search and apply for jobs, or needs an accommodation, please visit our accessibility site or contact us at Labcorp Accessibility. For more information about how we collect and store your personal data, please see our Privacy Statement.

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