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Bioinformatics Engineering Jobs in Chicago, IL (NOW HIRING)

The University of Chicago

Computational Biologist

Chicago, IL · On-site

$60K - $80K/yr

  • Medical

  • Retirement

  • PTO

Master's or doctoral degree in computational biology, bioinformatics, statistics, physics, or other ... Analytical, statistical, quantitative, and computational/programming skills. Application Documents

Tempus

Manager, Regulatory Submissions (Remote)

Chicago, IL · Remote

$110K - $150K/yr

Our Manager of Regulatory Affairs will work closely with our scientists, engineers, clinicians ... Ability to work well with quality, clinical, medical, bioinformatics, and laboratory teams across a ...

Tempus

Manager, Regulatory Submissions (Remote)

Chicago, IL · On-site +1

$110K - $150K/yr

Our Manager of Regulatory Affairs will work closely with our scientists, engineers, clinicians ... Ability to work well with quality, clinical, medical, bioinformatics, and laboratory teams across a ...

Tempus

Data Scientist II, Outcomes Research

Chicago, IL · On-site

$100K - $150K/yr

Partner with interdisciplinary groups of scientists, engineers, and product developers to translate ... Advanced degree (Master's with 2+ years experience or equivalent) in data science, bioinformatics ...

Tempus

Data Scientist II, Outcomes Research

Chicago, IL · On-site +1

$100K - $150K/yr

Partner with interdisciplinary groups of scientists, engineers, and product developers to translate ... Advanced degree (Master's with 2+ years experience or equivalent) in data science, bioinformatics ...

Tempus

Scientist II, Translational Research

Chicago, IL · On-site +1

$100K - $150K/yr

Work with Product and Engineering teams to streamline workflow of computational analyze Contribute ... Biostatistics/Statistical Genetics, Cancer Genetics,Bioinformatics, Computational Biology ...

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All JobsBioinformatics Engineering JobsBioinformatics Engineering Jobs in Chicago, IL

Bioinformatics Engineering information

See Chicago, IL salary details

$44.3K

$135K

$245.7K

How much do bioinformatics engineering jobs pay per year?

As of Aug 15, 2026, the average yearly pay for bioinformatics engineering in Chicago, IL is $135,004.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,900.00 and $161,700.00 per year, depending on experience, location, and employer.

What is the difference between Bioinformatics Engineering vs Bioinformatics Analyst?

AspectBioinformatics EngineeringBioinformatics Analyst
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related fields; programming skillsBachelor's or Master's in Bioinformatics, Biology, or related fields; data analysis skills
Work EnvironmentResearch labs, biotech companies, healthcare institutionsResearch institutions, healthcare, pharmaceutical companies
Employer & Industry UsageDevelops tools, pipelines, and software for data analysisInterprets data, generates reports, supports research projects

Bioinformatics Engineering focuses on developing software and pipelines for data processing, requiring programming expertise. In contrast, Bioinformatics Analysts primarily interpret data and generate insights, often with a stronger emphasis on biological knowledge. Both roles are vital in biotech and healthcare industries, but they differ in technical scope and daily tasks.

What is a bioinformatics engineer?

A bioinformatics engineer is a professional who develops and applies computational tools and techniques to analyze and interpret biological data, such as DNA sequences or protein structures. They combine expertise in computer science, biology, and mathematics to create software, manage databases, and solve complex biological problems. Bioinformatics engineers often work in research, pharmaceuticals, healthcare, and biotechnology industries to help advance scientific discoveries and medical innovations.

How do bioinformatics engineers typically collaborate with biologists and data scientists in a research setting?

Bioinformatics engineers frequently work in cross-disciplinary teams, partnering closely with biologists to understand experimental goals and with data scientists to analyze complex datasets. Effective communication is key, as engineers must translate biological questions into computational workflows and interpret results in a way that is meaningful to non-technical team members. This collaborative approach not only accelerates research but also helps engineers gain a deeper understanding of biological processes, which can lead to more innovative solutions and professional growth.

What are the key skills and qualifications needed to thrive as a bioinformatics engineer?

To thrive as a Bioinformatics Engineer, you need a solid background in biology, computer science, and statistics, often supported by a degree in bioinformatics or a related field. Familiarity with programming languages like Python or R, experience with bioinformatics tools (e.g., BLAST, GATK), and proficiency with databases and cloud computing platforms are typically required. Strong problem-solving, analytical thinking, and collaboration skills set standout professionals apart in this interdisciplinary field. These competencies are crucial for effectively analyzing complex biological data and driving innovation in life sciences research.

What do bioinformatics engineers do?

Bioinformatics engineers develop and implement computational tools and algorithms to analyze biological data, such as genetic sequences and molecular structures. They often work with programming languages like Python or R, utilize databases, and collaborate with biologists to interpret data for research and medical applications.

What are popular job titles related to Bioinformatics Engineering jobs in Chicago, IL?

For Bioinformatics Engineering jobs in Chicago, IL, the most frequently searched job titles are:

What job categories do people searching Bioinformatics Engineering jobs in Chicago, IL look for?

The top searched job categories for Bioinformatics Engineering jobs in Chicago, IL are:

What cities near Chicago, IL are hiring for Bioinformatics Engineering jobs?

Cities near Chicago, IL with the most Bioinformatics Engineering job openings:

Bioinformatics Engineering jobs near you
Infographic showing various Bioinformatics Engineering job openings in Chicago, IL as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $135,004 per year, or $64.9 per hour.

Computational Biologist

The University of Chicago

Chicago, IL • On-site

$60K - $80K/yr

Full-time

Medical, Retirement, PTO

Re-posted 15 days ago

University Of Chicago rating

8.1

Company rating: 8.1 out of 10

Based on 47 frontline employees who took The Breakroom Quiz

162nd of 618 rated colleges and universities

Job description

Department
BSD MED - Genetic Medicine - Im Research Staff
About the Department
The Section of Genetic Medicine shape the future of personalized medicine with successful research programs focused on the quantitative genetic and genomic science. The Section provides extremely valuable collaborations with investigators in the Department of Medicine who are seeking to develop new and more powerful ways to identify genetic risk factors for common, complex disorders with almost immediate clinical application.
The Section of Genetic Medicine conducts impactful investigations focused on quantitative genetics, systems biology and genomics, bioinformatics and computational biology as well as through extensive collaborations of the faculty throughout the Department of Medicine, Biological Sciences Division and the University of Chicago.
Job Summary
We are seeking a lifelong learner interested in developing statistical and computational tools to sift through large amounts of data to make discoveries that can improve human health. The Computational Biologist will contribute to the development and application of statistical and computational tools across NIH-funded projects, integrating large-scale GWAS with metabolomics data to uncover mechanisms underlying complex diseases and developing polygenic risk scores that transfer genetic signals across human populations and model organisms to study addiction-related traits, COPD, type 2 diabetes, and other common diseases.
Responsibilities
  • Analyze large-scale genomic datasets including RNA-seq, whole genome sequence, and single-cell data.
  • Develop and apply statistical and computational methods to extract biological insights from high-dimensional data.
  • Develop and train deep learning models to improve upon traditional statistical methods in genomics.
  • Collaborate with disease and genomics experts to address pressing biomedical research questions.
  • Write and contribute to scientific publications and present findings at lab and consortium meetings.
  • Help train and mentor students in the lab.
  • Applies research principles and relevant subject matter knowledge relevant to administer a research project. With a moderate level of direction, manages lab and/or research-related duties and tasks. Helps develop, design and conduct research projects according to plan.
  • Takes responsibility for the following laboratory duties: recognizing abnormal results and varying conditions or procedures to correct problems; setting up and performing experiments. Analyze the meaning, significance, causes, and effects of the subject.
  • Performs other related work as needed.

Minimum Qualifications
Education:
Minimum requirements include a college or university degree in related field.
Work Experience:
Minimum requirements include knowledge and skills developed through 2-5 years of work experience in a related job discipline.
Certifications:
---
Preferred Qualifications
Education:
  • Master's or doctoral degree in computational biology, bioinformatics, statistics, physics, or other quantitative disciplines with an interest in applying skills to biomedical research.

Experience:
  • Experience with deep learning in genomics and large language models.
  • Experience with large datasets, distributed computing, and databases.
  • Reproducible research tools and workflows (GitHub, Snakemake, Nextflow).
  • Proficiency in R and/or Python.

Preferred Competencies
  • Strong Analytical skills.
  • Problem-solving skills.
  • Organizational skills.
  • Verbal and written communication skills.
  • Ability to work independently and as part of a team
  • Willingness to explore and adopt new ideas and technologies.
  • Analytical, statistical, quantitative, and computational/programming skills.

Application Documents
  • Resume (required)
  • Cover Letter (required)

When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Job Family
Research
Role Impact
Individual Contributor
Scheduled Weekly Hours
40
Drug Test Required
No
Health Screen Required
No
Motor Vehicle Record Inquiry Required
No
Pay Rate Type
Salary
FLSA Status
Exempt
Pay Range
$60,000.00 - $80,000.00
The included pay rate or range represents the University's good faith estimate of the possible compensation offer for this role at the time of posting.
Benefits Eligible
Yes
The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.
Posting Statement
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.

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