ZipRecruiter

Log In

1

Bio Scientist Jobs (NOW HIRING)

next page

Showing results 1-20

All JobsScience JobsBiology JobsScientist JobsBio Scientist Jobs

Bio Scientist information

What cities are hiring for Bio Scientist jobs?

Cities with the most Bio Scientist job openings:

What states have the most Bio Scientist jobs?

States with the most job openings for Bio Scientist jobs include:

What are popular job titles related to Bio Scientist jobs?

For Bio Scientist jobs, the most frequently searched job titles are:

Infographic showing various Bio Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 84% Full Time, 10% Part Time, and 4% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution.

E11 Bio - Scientist/Senior Scientist, Molecular Engineering & Sample Optimization

Alameda, CA • On-site

Convergent Research
See more jobs at Convergent Researchexternal

$125 - $150/hr

Other

Retirement

Posted 27 days ago

Job description

E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our technology roadmap.

Responsibilities

  • Develop and deploy an assay to systematically evaluate and improve the fixation quality and preservation of brain tissue

  • Establish and integrate quantitative metrics of molecular readout e.g. protein retention, antigenicity, and labeling quality across tissue preparation conditions

  • Work closely with in vivo research technicians to design experiments, evaluate results, and optimize SOPs

  • Drive the development of data-analysis pipelines to routinely generate key performance indicators of sample tissue quality

  • Generate an in-house pipeline for binder design/discovery, validation, and optimization of epitope-binder pairs in hydrogels to improve the readout of epitope barcode bits and relevant native synaptic proteins

  • Develop novel highly multiplexed protein readout strategies for protein barcodes and molecular annotation of synapses and cell types

Outcomes In the first 6 Months

  • Defined key indicators for perfusion quality and deploy an assay to routinely capture these.

  • Incorporated protein retention, antigenicity, and specificity as per-stage metrics across the sample generation pipeline.

  • Deployed early perfusion or fixed tissue readout metrics that predict the final expanded tissue quality, including both overall preservation and specific markers of cellular health

  • Recorded a measurable > 20%improvement in expanded ultrastructural image contrast compared to current baseline perfusion & gelation protocol

  • First new epitope-binder designs in production

  • Developed assay for binder compatibility in expanded tissue, and validated this assay against existing pairs

  • Identified and validated a cocktail of binders for identifying most synapses via e.g. synaptic vesicle binding

In 12 Months:

  • Evaluated the first set of designed epitope-binder pairs and synaptic protein-binder pairs and qualified in expanded tissue, 5+ binders exceeding commercial SOTA performance.

  • With collaborators, improved the multiplexed readout strategy to allow for routine incorporation into the imaging pipeline and a demonstrated increase in key barcode metrics (e.g. imaging speed or entropy increases)

  • Identified and validated multiple cocktails of binders for stratifying excitatory and inhibitory synapses

$100,000 - $191,000 a year

Scientist base salary range: $100K - 165K

Senior Scientist base salary range: $127K - 191K

This position is eligible for a team performance based bonus up to 20% of base salary and a 401k match up to 6% of base salary.

Total potential compensation range: $126K - 240K

E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.

#J-18808-Ljbffr

Apply