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Best Paying Rn Jobs in Columbia, SC (NOW HIRING)

PruittHealth

Registered Nurse

Columbia, SC · On-site

If you're searching for a high-paying RN Home Health job with flexible scheduling and strong clinical support, this is the place for you. Why Home Health RNs Love Working With Us * Topofmarket RN pay ...

PruittHealth

Registered Nurse

Columbia, SC · On-site

If you're searching for a high-paying RN Home Health job with flexible scheduling and strong clinical support, this is the place for you. Why Home Health RNs Love Working With Us * Top-of-market RN ...

PruittHealth

Registered Nurse

Columbia, SC · On-site

If you're searching for a high-paying RN Home Health job with flexible scheduling and strong clinical support, this is the place for you. Why Home Health RNs Love Working With Us * Top‑of‑market ...

Anders Group

Travel ER RN

Columbia, SC · On-site

Anders Group is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel OR RN

Camden, SC · On-site

Anders Group is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel OR RN

Camden, SC · On-site

Anders Group is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Discipline: RN * Start Date: 09/28/2026 * Duration: 13 weeks * 36 hours per week * Shift: 12 hours ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Discipline: RN * Start Date: 09/21/2026 * Duration: 13 weeks * 48 hours per week * Shift: 12 hours ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel MS/Telemetry RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Anders Group is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

New

Anders Group

Travel OR RN

Camden, SC · On-site

Anders Group is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Anders Group is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel Cardiac Stepdown RN

Columbia, SC · On-site

Anders Group is seeking a travel nurse RN Cardiac Stepdown for a travel nursing job in Columbia ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel Stepdown Cardiac RN

Columbia, SC · On-site

Anders Group is seeking a travel nurse RN Cardiac Stepdown for a travel nursing job in Columbia ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Discipline: RN * Start Date: 09/21/2026 * Duration: 13 weeks * 48 hours per week * Shift: 12 hours ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Discipline: RN * Start Date: 09/28/2026 * Duration: 13 weeks * 36 hours per week * Shift: 12 hours ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel Cath Lab RN

Columbia, SC · On-site

Anders Group is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

Anders Group

Travel LTAC Med Surg Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Anders Group is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

New

Anders Group

Travel LTAC Med Surg Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Anders Group is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

New

Anders Group

Travel LTAC Med Surg Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

Anders Group is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

New

Anders Group

Travel CCU RN

Columbia, SC · On-site

Anders Group is seeking a travel nurse RN Long Term Acute Care CCU - Coronary Care for a travel ... the best-paying travel opportunities nationwide. What You Can Expect From your very first ...

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Showing results 1-20

All JobsBest Paying Rn JobsBest Paying Rn Jobs in Columbia, SC

Best Paying Rn information

See Columbia, SC salary details

$18

$41

$68

How much do best paying rn jobs pay per hour?

As of Sep 5, 2026, the average hourly pay for best paying rn in Columbia, SC is $41.15, according to ZipRecruiter salary data. Most workers in this role earn between $31.15 and $48.03 per hour, depending on experience, location, and employer.

What are the best paying RN jobs?

The best paying RN (Registered Nurse) jobs are typically found in specialized fields such as nurse anesthetists, nurse practitioners, critical care, emergency room, and surgical nursing. RNs working in high-demand locations, such as California or major metropolitan areas, often earn higher salaries. Additionally, nurses working in management, administration, or with advanced degrees tend to command higher pay. Factors like experience, certifications, and shift differentials (such as night shifts) can also significantly impact earning potential.

What skills and qualifications are needed to thrive as a high-earning Registered Nurse?

To excel as a high-paying Registered Nurse, you need advanced clinical expertise, strong patient care abilities, and typically a Bachelor of Science in Nursing (BSN) or higher, along with RN licensure and specialty certifications. Familiarity with specialized medical equipment, electronic health records (EHRs), and advanced life support systems is often required for top-paying roles. Leadership, critical thinking, and excellent interpersonal skills distinguish candidates in competitive, high-stakes environments. These qualifications enable RNs to deliver expert care in specialized fields, assume greater responsibility, and contribute to improved patient outcomes and organizational success.

What types of healthcare settings offer the highest earning potential for Registered Nurses?

Registered Nurses seeking top pay often find the highest earning potential in specialized settings such as intensive care units, operating rooms, and emergency departments, as well as in travel nursing, outpatient surgical centers, and private sector roles. Hospitals in metropolitan areas, especially those facing nursing shortages, may also offer higher wages, sign-on bonuses, or differential pay for night and weekend shifts. Additionally, RNs with advanced certifications or those who pursue management or nurse practitioner roles often see increased compensation. Exploring these paths can help maximize both salary and career growth opportunities.

What is the difference between Best Paying Rn vs Registered Nurse?

AspectBest Paying RnRegistered Nurse
Average SalaryHigher, often in specialized fields or locationsStandard, varies by experience and location
CertificationsRequires RN license; additional certifications may boost payRN license; certifications can enhance salary
Work EnvironmentHospitals, specialized clinics, travel nursingHospitals, clinics, long-term care facilities
Job DemandHigh in specialized areas like ICU, OR, or travel nursingConsistent demand across healthcare settings

The Best Paying Rn typically earns more due to specialization, location, or additional certifications. While both roles require an RN license, those in specialized fields or travel nursing tend to have higher salaries compared to general Registered Nurses. Choosing a specialization or working in high-demand areas can significantly impact earning potential.

What cities near Columbia, SC are hiring for Best Paying Rn jobs?

Cities near Columbia, SC with the most Best Paying Rn job openings:

Best Paying Rn jobs near you
Infographic showing various Best Paying Rn job openings in Columbia, SC as of August 2026, with employment types broken down into 1% As Needed, 74% Full Time, 19% Part Time, and 6% Contract. Highlights an 90% Physical, 2% Hybrid, and 8% Remote job distribution, with an average salary of $85,598 per year, or $41.2 per hour.

Registered Nurse

PruittHealth

Columbia, SC • On-site

Full-time

Medical, Retirement

Re-posted 12 days ago

PruittHealth rating

6.0

Company rating: 6.0 out of 10

Based on 135 frontline employees who took The Breakroom Quiz

125th of 247 rated social care providers

Job description

Registered Nurse (RN) - Home Health

Full Time- 3 openings

Locations 1- Lexington

                   1- Kershaw/Fairfield

                    1- Richland County

PruittHealth @ Home is hiring compassionate Home Health Registered Nurses (RNs) who want a career that offers worklife balance, autonomy, and meaningful oneonone patient care.

If you're searching for a high-paying RN Home Health job with flexible scheduling and strong clinical support, this is the place for you.

Why Home Health RNs Love Working With Us

  • Topofmarket RN pay mileage reimbursement
  • Flexible schedules - manage your own day
  • Paid training Preceptorship Program
  • Health benefits 401(k)
  • Annual merit increases
  • Supportive leadership & strong clinical resources
  • Career growth in one of the fastestgrowing RN specialties

What You'll Do

As a Home Health RN Case Manager, you will:

  • Provide skilled nursing visits in the patient's home
  • Complete assessments, start-of-care visits, and care plans
  • Collaborate with the interdisciplinary care team
  • Supervise LPNs and Home Health Aides
  • Document care using an iPad with AI assist (OASIS experience a plus)
  • Educate patients and families to promote independence
  • Ensure continuity, quality, and safety of patient care

What We Require

  • Active, unrestricted Registered Nurse (RN) license
  • Valid driver's license & reliable transportation
  • CPR certification
  • 1 year of RN experience (home health or acute care preferred)

Preferred Experience

  • Experience with aging or adult patient populations
  • Highly organized with strong time-management skills; able to multitask, prioritize a busy caseload, and work confidently with technology and electronic documentation systems

Ready to Make a Real Impact?

Join a team where family, compassion, and highquality care come first.
Apply today to grow your RN Home Health career with PruittHealth @ Home.

Family Makes Us Stronger. Our family, your family, one family. Committed to loving, giving, and caring. United in making a difference.

We are eager to connect with you! Apply Now to get started at PruittHealth!

As an Equal Employment Opportunity employer, all qualified applicants will receive consideration without regard to race, color, religion, sex, national origin, disability, or veteran status.

For Florida Job Postings Only:

For more information regarding Florida's Care Provider Background Screening Clearinghouse Education and Awareness, please visit https://info.flclearinghouse.com

What PruittHealth employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About PruittHealth

Sourced by ZipRecruiter

PruittHealth will help you conquer your career goals. At PruittHealth, we are searching for nurses who are committed to serving our residents with care and compassion, and in return, we are committed to supporting your nursing career through annual merit increases, career growth programs, preceptorship, and more.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Norcross, GA, US

Year founded

1969

Social media

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