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Associate Scientist Cell Line Development Jobs in Santa Clara, CA

ATUM

Technical Field Applications Scientist

Newark, CA · On-site

$120K - $150K/yr

ATUM is a leader in cell line development, gene synthesis, and protein engineering. We are seeking a highly motivated, Technical Field Applications Scientist (FAS) to join our team. Job Summary: The ...

Immunedge Inc

Head of CMC

Redwood City, CA · On-site

$277K - $416K/yr

... science. We are building a culture based on kindness, collaboration, and a deep passion for ... Scope covers CMC strategy, cell line and process development, analytical development and ...

System One

Associate Scientist

Fremont, CA · On-site

$22 - $25/hr

Associate Scientist - Mammalian Cell Culture Location: Fremont, CA Pay Rate: $22-25/hour Hours : M-F 8AM-5PM Type: 6 Month Contract potential for hire Overview Biopharmaceutical Division of a Global ...

ImmunEdge, Inc

Head of CMC

Redwood City, CA · On-site

$277K - $416K/yr

... science. We are building a culture based on kindness, collaboration, and a deep passion for ... Scope covers CMC strategy, cell line and process development, analytical development and ...

ImmunEdge, Inc

Head of CMC

Redwood City, CA · On-site

$300 - $380/hr

... science. We are building a culture based on kindness, collaboration, and a deep passion for ... Scope covers CMC strategy, cell line and process development, analytical development and ...

Orion Group

Associate Scientist I

San Mateo, CA · On-site

$36 - $40/hr

The Associate Scientist I will be a member of the CMC Biologics Cell Culture Development group, responsible for providing support for the development of novel biologics and bioprocess innovation ...

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All JobsAssociate Scientist Cell Line Development JobsAssociate Scientist Cell Line Development Jobs in Santa Clara, CA

Associate Scientist Cell Line Development information

See Santa Clara, CA salary details

$22

$42

$67

How much do associate scientist cell line development jobs pay per hour?

As of Aug 23, 2026, the average hourly pay for associate scientist cell line development in Santa Clara, CA is $42.19, according to ZipRecruiter salary data. Most workers in this role earn between $32.74 and $47.98 per hour, depending on experience, location, and employer.

What does an associate scientist in cell line development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What are the key skills and qualifications needed to thrive as an associate scientist in cell line development?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.

What are some common challenges faced by associate scientists in cell line development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What cities near Santa Clara, CA are hiring for Associate Scientist Cell Line Development jobs?

Cities near Santa Clara, CA with the most Associate Scientist Cell Line Development job openings:

Associate Scientist Cell Line Development jobs near you

Associate Scientist/Scientist Cell-Based Assays & In Vivo Oncology (Temporary to direct)

Aragen Life Sciences

Morgan Hill, CA • On-site

$80K - $110K/yr

Full-time, Temporary

Posted 17 days ago

Job description

About Us
Aragen Bioscience is a leading contract research organization focused on accelerating product development. Aragen's offerings include pre-clinical efficacy studies and cell-based assays as well as antibody discovery, recombinant protein production, and purification and stable cell line development. We offer clients high quality service and superior R&D partnerships.
Job Title
Associate Scientist - Cell-Based Assays & In Vivo Oncology (temporary to direct)
We are seeking an Associate Scientist/Scientist with strong hands-on proficiency in cell-based assay development and execution, together with demonstrated experience managing in vivo tumor models. The successful candidate will work under the direction of a director.
Essential Functions
The successful candidate will be responsible for the design, execution, and troubleshooting of cell-based assays and for the day-to-day management of in vivo tumor efficacy studies supporting preclinical oncology programs. The candidate will be an innovative, independent and motivated professional. Cell-based assay responsibilities include development, qualification, and routine execution of viability, proliferation, cytotoxicity, ADCC/CDC, reporter, and target-engagement assays; maintenance of primary and immortalized cell cultures and cell banks; ELISA/MSD, Western blot/JESS, flow cytometry, and quantitative PCR; and inventory and tracking of samples generated by preclinical projects.
In vivo responsibilities include tumor cell preparation, management of xenograft and syngeneic tumor models (including tumor measurement and body-weight monitoring, dosing by multiple routes [IP, IV, PO, SC], randomization and study scheduling, terminal procedures, and tissue and blood collection for downstream analysis). The candidate will maintain accurate study records, support IACUC protocol preparation and amendments, and work in full compliance with applicable animal welfare regulations. The candidate will have experience with troubleshooting assays and should be capable of data analysis, data presentation, managing multiple projects and interested in learning new areas of research. In vitro and cell-based assay responsibilities will constitute ~80% of effort, and in vivo pharmacology 20%.
Requirements
Basic Qualifications, Skills, & Abilities
  • MS or PhD in Biology, Cell Biology, Immunology, Pharmacology, or a related life science discipline
  • 3+ years' hands-on experience developing and running cell-based assays within a drug discovery organization or CRO (PhD) or 7+ years (MS)
  • Deep knowledge of cell and molecular biology techniques, including sterile technique, and assay troubleshooting and optimization
  • Demonstrated experience managing in vivo tumor models, including xenograft and/or syngeneic mouse studies, with proficiency in tumor implantation, caliper measurement, dosing (IP, IV, PO, SC), and terminal procedures
  • Working knowledge of IACUC protocol preparation and applicable animal welfare regulations
  • Strong data analysis and presentation skills, including dose-response and tumor-growth-inhibition analysis in GraphPad Prism or equivalent, with accurate record keeping
  • Working in an environment of teamwork and collaboration
  • Excellent communication and interpersonal skills and proven success working in matrix environments

Aragen Bioscience provides a stimulating work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. We are located in Morgan Hill, California, at the south end of the Silicon Valley. Great reverse Commute! We offer excellent salaries and benefits. Aragen is an equal opportunity employer
Salary Description
80,000 to 110,000 Depending on experience

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