Genscript is seeking a motivated and detail-oriented HTP Analytical QC Associate Scientist to join our dynamic US Protein Department in Piscataway, New Jersey.
The estimated salary range is $60,000 - $75,000, depending on experience.Â
Reporting to: Supervisor of HTP Platform
Employment Type: Full-time
Role Description:
We are seeking a detail-oriented and proactive Associate Scientist to join our High-Throughput Protein Analytical QC Laboratory. This role is responsible for performing analytical characterization and quality control testing of recombinant proteins generated from high-throughput production workflows.
The successful candidate will play a critical role in ensuring protein identity, purity, and overall quality through robust analytical methodologies. This position operates in a data-driven and quality-focused environment where accuracy, reproducibility, and data integrity are essential. The ideal candidate will have hands-on experience with protein analytical techniques and familiarity with laboratory data management systems such as ELN, LIMS, or equivalent platforms.
Key Responsibilities:
- Perform routine and non-routine analytical and QC testing to evaluate protein identity, purity, and quality attributes.
- Execute a range of protein characterization assays, including:
- HPLC / UPLC (e.g., SEC, RP, IEX)
- Capillary Electrophoresis (CE, iCE/cIEF)
- SDS-PAGE
- Western blot
- LC-MS
- Endotoxin assays
- Prepare samples, reagents, buffers, and standards in accordance with established protocols and assay requirements.
- Perform sample preparation workflows, including use of automated liquid handling systems where applicable.
- Analyze, interpret, and document experimental data in ELN, LIMS, or equivalent systems, ensuring compliance with data integrity standards (e.g., ALCOA+ principles).
- Support method troubleshooting and optimization, ensuring assay robustness, reproducibility, and consistency across runs.
- Maintain laboratory instruments and ensure proper calibration and performance, supporting compliance with quality and safety standards.
- Collaborate with cross-functional teams (e.g., protein production, process development) to support project timelines and deliverables.
- Contribute to continuous improvement initiatives, including method refinement, workflow efficiency, and data quality enhancement.
Qualifications:
- BS or MS in Biochemistry, Analytical Chemistry, Biotechnology, or a related field with 2+ years of relevant experience in protein analytical characterization or QC.
- Hands-on experience with protein analytical techniques such as HPLC/UPLC, CE, SDS-PAGE, Western blot, LC-MS, or endotoxin assays.
- Familiarity with protein characterization workflows, including purity, aggregation, and identity analysis.
- Experience with laboratory data systems (ELN, LIMS, or similar) and strong documentation practices.
- Strong attention to detail and commitment to data integrity, accuracy, and reproducibility.
- Experience in a CRO/CDMO or regulated QC environment is preferred.
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