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Associate Downstream Processing Scientist Jobs in Indiana

Pacelabs

Formulation Associate Scientist

Indianapolis, IN · On-site

$23 - $25/hr

This Associate Scientist will work under the guidance of senior scientists to execute formulation ... Support process development activities for a variety of dosage forms, including sterile injectable ...

Pace

Formulation Associate Scientist

Indianapolis, IN · On-site

$23 - $25/hr

This Associate Scientist will work under the guidance of senior scientists to execute formulation ... Support process development activities for a variety of dosage forms, including sterile injectable ...

Brotherhood Mutual

Associate Data Scientist

Fort Wayne, IN · On-site

$58K - $58K/yr

Associate Data Scientist FLSA Status: Exempt Job Family: Research & Development Department ... Execute the production of statistical models, tools, and processes. * Write programs to cleanse and ...

Brotherhood Mutual

Associate Data Scientist

Fort Wayne, IN · On-site

$58K - $58K/yr

Associate Data Scientist FLSA Status: Exempt Job Family: Research & Development Department ... Execute the production of statistical models, tools, and processes. * Write programs to cleanse and ...

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All JobsAssociate Downstream Processing Scientist JobsAssociate Downstream Processing Scientist Jobs in Indiana

Associate Downstream Processing Scientist information

What is the difference between Associate Downstream Processing Scientist vs Associate Upstream Processing Scientist?

AspectAssociate Downstream Processing ScientistAssociate Upstream Processing Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Skills & CertificationsProtein purification, chromatography, GMP complianceCell culture, bioreactor operation, aseptic techniques
Work EnvironmentLaboratories, manufacturing facilitiesBioreactors, cell culture labs
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical research and production

Both roles are essential in biopharmaceutical production, with the Associate Downstream Processing Scientist focusing on purification processes, while the Associate Upstream Processing Scientist handles cell growth and fermentation. They often collaborate within the same production pipeline, but their skill sets and daily tasks differ based on their specific focus areas.

What are the most commonly searched types of Downstream Processing Scientist jobs in Indiana?

The most popular types of Downstream Processing Scientist jobs in Indiana are:

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Associate Downstream Processing Scientist jobs near you
Infographic showing various Associate Downstream Processing Scientist job openings in Indiana as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 25% Part Time, 1% Temporary, and 1% Contract. Highlights an 96% Physical, 2% Hybrid, and 2% Remote job distribution.

Mixed Modality (Peptide Downstream) Scientist - Process Translation and Execution

Scorpion Therapeutics

Indianapolis, IN • On-site

$66 - $172/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 8 days ago

Job description

Responsibilities:
  • Evaluate and facilitate transfer of peptide downstream manufacturing processes from development labs to pilot plant operations (kilo-scale and isolator environments) for early-phase cGMP API (grams–kilograms) clinical supply.
  • Perform peptide purification/isolation; assess purification methods.
  • Use peptide downstream procedures: reverse-phase chromatography, TFF, lyophilization, precipitation & drying.
  • Evaluate safety of incoming procedures with safety and process engineering.
  • Order/stage chemicals; obtain reference materials and set up analytical methods.
  • Reprocess/analyze analytical data; summarize/present chemistry and challenges.
  • Execute plant familiarization steps; perform use-tests and document Definitive Lab Trials to confirm plant readiness.
  • Maintain detailed lab notebooks for technical packages and replication.
  • Author/review tech transfer plan, SOPs, batch records, campaign summary and deviation reports.
  • Apply process improvement; support troubleshooting, deviations/quality events/non-conformances; perform RCA and CAPAs.
Qualifications (Required):
  • B.S./M.S. in chemistry, chemical engineering, or related.
  • 3+ years peptide purification and/or manufacturing experience (synthetic peptide API/drug substance); reverse-phase chromatography preferred.
  • Authorized to work in the U.S. full-time; no visa sponsorship.
Preferred:
  • Peptide downstream knowledge; purification/purification scale-up experience; chromatography/TFF proficiency; downstream conjugation/cyclization.
  • Comfort with preparative columns/TFF; attention to detail; batch record/scale-up experience.
  • HPLC/UPLC, LC-MS, GC, NMR; mass balance.
  • Cross-functional communication; QA/safety collaboration.
Location/Info:
  • Initially Indianapolis/Carmel; permanent Lebanon, IN; travel <5%; manufacturing/lab environment.
Compensation/Benefits (as stated):
  • Anticipated wage: $66,000–$171,600; possible company bonus; comprehensive benefits (401(k), pension, vacation, medical/dental/vision, flexible benefits, life insurance, time off/leave, well-being).
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