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Associate Director Translational Science information

What does an associate director translational science do?

An Associate Director of Translational Science leads and manages research projects that bridge basic scientific discoveries and clinical applications in areas such as drug development or disease treatment. They collaborate with multidisciplinary teams to design and implement studies, analyze data, and ensure that findings can move efficiently from the laboratory to patient care. This role often involves overseeing regulatory compliance, managing budgets, and mentoring junior scientists. The Associate Director plays a key role in advancing innovative therapies and supporting the organization's strategic research goals.

What are the key skills and qualifications needed to thrive as an associate director translational science?

To thrive as an Associate Director Translational Science, you need a strong background in biomedical sciences, drug development, and project management, typically supported by a PhD or advanced degree in a relevant field. Familiarity with bioinformatics tools, laboratory information management systems (LIMS), and regulatory compliance standards is often required. Strong leadership, cross-functional communication, and problem-solving skills help drive collaboration between research and clinical teams. These competencies are crucial for effectively translating scientific discoveries into clinical applications and advancing therapeutic programs.

What are some common challenges faced by an associate director translational science when bridging preclinical and clinical research teams?

One of the main challenges is ensuring clear and effective communication between diverse teams, such as laboratory scientists and clinical trial coordinators, who may have different technical backgrounds and priorities. As an Associate Director, you'll often need to translate complex scientific findings into actionable clinical strategies, ensuring that research is aligned with regulatory requirements and patient needs. Balancing innovation with compliance, managing cross-functional projects, and keeping timelines on track are also central to the role. Successful candidates are those who can foster collaboration, adapt to evolving project goals, and anticipate potential obstacles in drug development pipelines.

What is the difference between Associate Director Translational Science vs Associate Director Clinical Research?

AspectAssociate Director Translational ScienceAssociate Director Clinical Research
Primary FocusBridging laboratory research to clinical applications, developing translational strategiesManaging clinical trial operations, ensuring regulatory compliance
Required CredentialsPhD or equivalent in life sciences, experience in translational researchMaster's or PhD in life sciences, clinical research experience
Work EnvironmentResearch labs, collaborative with scientists and cliniciansClinical trial sites, CROs, pharmaceutical companies
Industry UsageBiotech, pharma, research institutionsPharmaceutical companies, CROs, biotech firms

The Associate Director Translational Science focuses on transforming laboratory findings into clinical applications, while the Associate Director Clinical Research oversees the execution of clinical trials. Both roles require advanced degrees and industry experience but differ in their core responsibilities and work settings.

What are the career paths in associate director translational science?

Career paths for an Associate Director in Translational Science often lead to senior leadership roles such as Director, Vice President, or Head of Translational Research, with opportunities to specialize in areas like biomarker development, clinical strategy, or regulatory affairs. Progression typically involves gaining experience in project management, scientific expertise, and cross-functional collaboration, often supported by advanced degrees and industry certifications. Advancement depends on demonstrated leadership, successful project execution, and industry experience within pharmaceutical or biotech environments.

What cities in Connecticut are hiring for Associate Director Translational Science jobs?

Cities in Connecticut with the most Associate Director Translational Science job openings:

Infographic showing various Associate Director Translational Science job openings in Connecticut as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 25% Part Time, 1% Temporary, and 1% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution.

Associate Director, Translational Research and Non-Clinical Lead - Translational Sciences

Branford, CT • On-site

EvolveImmune Therapeutics, Inc.
Biotechnology Research and Development • 1 - 10 employees
Learn more about EvolveImmune Therapeutics, Inc.external

Other

PTO

Re-posted 8 days ago

Key responsibilities

  • Develop and implement strategies for translational and non-clinical safety and pharmacology assessments to support clinical positioning and IND-enablement of development candidates

  • Oversee the generation of data from patient-derived tissue samples, organoids, and in vitro assays such as MABEL and safety assays

  • Manage CRO partnerships, study design, monitoring, and data reporting to ensure successful execution of non-clinical studies

Job description

Associate Director, Translational Research and Non-Clinical Lead – Translational Sciences

Associate Director, Translational Research and Non-Clinical Lead Translational Sciences
Location: Branford, CT – Onsite

Join a company where your science will directly shape the future of cancer immunotherapy.

Who We Are

EvolveImmune Therapeutics is a privately-held, next-generation immuno-oncology company pioneering a new class of T cell engager therapies to transform cancer patient outcomes compared to current immunotherapies. Our first-in-category biotherapeutic EVOLVE platform utilizes integrated T cell costimulation to directly target tumor cells to deliver durable anti-tumor adaptive immune responses. Our lead asset, EVOLVE104, entered clinical trials in late 2025. Additional collaboration pipeline programs (with Abbvie) and wholly owned programs are progressing toward candidate nomination. EvolveImmune’s team consists of ~50 FTEs in R&D, business development, human resources and operations with immediate plans for additional growth. Our newly expanded, state-of-the-art 20,000+ square foot laboratory and office space located in the New Haven, CT biotechnology corridor is convenient to the amenities of the Connecticut shoreline, the city of New Haven and easy travel options throughout the Boston/New York City corridor.

We’re hiring anAssociate Director, Translational Research and Non-Clinical Lead to join our collaborative Translational Sciences team to lead the translational research and non-clinical development for our rapidly advancing EVOLVE project portfolio. The successful candidate will develop and implement the strategy for translational and non-clinical safety/pharmacology assessments to support the clinical positioning and IND-enablement of our development candidates. The successful candidate will work with patient-derived tissue samples and organoids to generate insights into the differentiation and mode of action of our emerging assets. The candidate will oversee junior laboratory scientists supporting translational research as well as generation of data for non-clinical in vitro assays such MABEL and in vitro safety assays. Experience with bioinformatics is a plus. Strong collaboration and communication skills, leadership in supervising and mentoring junior scientists, and a track record of scientific and project achievements in biopharma, are required.

We value curiosity, collaboration, and diverse perspectives—if you’re excited by our mission but unsure if you meet every requirement, we encourage you to apply.

What You’ll Work On
  • Establish organoids/primary cell systems to evaluate drug responses in complex human tissues
  • Evaluate target expression including development of IHC assay
  • Define and execute the non-clinical safety, pharmacology and toxicology strategy for each program including overseeing dose modeling, establishing exposure response and determining efficacious and FiH doses
  • Lead efforts to plan and execute in-house and external IND enabling studies with adherence to GLP (Good Laboratory Practice) and other regulatory guidelines where appropriate
  • Manages CRO partnerships, study design, monitoring, and data reporting
  • Partner with the Immunobiology, Biotherapeutics teams to facilitate the progression of programs from discovery to clinical development
  • Partner with Regulatory, CMC and Clinical Development teams to support IND
  • Prepare documentation for regulatory submissions, including INDs
  • Mentor our scientific team and support individual career development for team members
  • Contribute to our company’s communication strategy to drive the visibility and recognition of our scientific strategy and company milestones in presentations to our Board of Directors, investors, collaboration partners, and through presentations at external scientific conferences
  • Work with project management to develop timelines and budgets, and ensure deliverables are achieved in a timely fashion
  • Ensure compliance with all health and safety protocols
What You Bring
  • PhD in Immunology or related field with at least 5 years of relevant industry experience
  • Experience in working with primary human tissues/model, oncology biologic drug safety, pharmacology and toxicology assessments and successful submissions of regulatory documents (INTERACT/pre-IND) and non-clinical study packages to FDA
  • Proven ability to manage complex projects to achieve milestones in a timely manner, including managing internal work, collaborations with external consultants and CROs
  • Strong verbal and written communication and presentation skills
  • Track record of success as defined by publication, patent and/or drug development record
What You’ll Gain
  • A hands-on, high-impact role shaping the design of next-generation immunotherapies
  • Opportunity to see your work move rapidly from concept to clinic
  • A visible position within the Translational Science team, contributing directly to platform and pipeline innovationA chance to collaborate across disciplines and influence key program decisions
  • Professional growth through exposure to diverse scientific challenges and cross-functional projects
  • Mentorship opportunities and the ability to help shape a growing discovery organization
  • A mission-driven, fast-paced biotech environment that values bold thinking and scientific excellence
  • A supportive, open culture built on collaboration, trust, and shared purpose
Why You’ll Love Working Here
  • Direct impact: Your ideas and experiments will influence platform design and help shape clinical programs
  • Cutting-edge science: Work on a truly novel immunotherapy approach in a scientifically rigorous, fast-moving environment
  • Personal growth: Take on visible high‑impact projects in a startup culture where contributions are recognized and development is supported
  • Collaborative culture: Join a tight‑knit, mission‑driven team that values open communication, learning, and teamwork
  • Top‑tier facilities: Enjoy working in our brand‑new, purpose‑built lab space just outside New Haven, CT
  • Mission with meaning: Be part of a company working to give more patients real hope in the fight against cancer
Additional Info
  • This is a full‑time, onsite position based in Branford, CT
  • EvolveImmune requires COVID-19 vaccination; medical and religious accommodations will be considered
  • We offer competitive salary, benefits, equity, and paid time off
  • We are an equal opportunity employer and value diverse perspectives in all aspects of our work
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