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Analytical Method Validation Jobs in Massachusetts

Living Proof Inc

Analytical Chemist

Boston, MA · On-site

$100K - $120K/yr

Responsibilities include analytical method development and validation, investigating complex analytical problems, supporting quality activities, and contributing to product claims substantiation. The ...

Living Proof, Inc.

Analytical Chemist

Boston, MA · On-site

$100K - $120K/yr

Responsibilities include analytical method development and validation, investigating complex analytical problems, supporting quality activities, and contributing to product claims substantiation. The ...

Eateam

chemist

Lawrence, MA

Write protocols and execute analytical method validations. Develop and execute testing protocols. Support exploratory testing to define test equipment, test fixtures and test methods development.

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Showing results 21-40

All JobsAnalytical Method Validation JobsAnalytical Method Validation Jobs in Massachusetts

Analytical Method Validation information

See Massachusetts salary details

$24

$56

$85

How much do analytical method validation jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for analytical method validation in Massachusetts is $56.79, according to ZipRecruiter salary data. Most workers in this role earn between $43.08 and $69.04 per hour, depending on experience, location, and employer.

What is an analytical method validation?

An Analytical Method Validation job involves developing, assessing, and documenting laboratory methods to ensure they produce reliable and accurate results. Professionals in this role validate methods according to regulatory guidelines (such as ICH, USP, or FDA) by evaluating parameters like accuracy, precision, specificity, and robustness. They work in industries like pharmaceuticals, biotechnology, and chemicals to ensure compliance with quality standards. The role also requires troubleshooting analytical issues and maintaining validation records to support regulatory audits.

What does a typical day look like for someone working in analytical method validation?

A typical day in Analytical Method Validation involves developing and executing protocols to verify that laboratory methods are reliable, accurate, and consistent with industry regulations. You'll spend time in the lab conducting experiments, analyzing sample data, documenting results, and preparing detailed validation reports for regulatory submission. Collaborating with quality assurance, regulatory teams, and other scientists is common to address findings and ensure alignment with project goals. This role combines hands-on technical work with critical data review and cross-disciplinary teamwork, offering a dynamic and intellectually engaging work environment.

What are the key skills and qualifications needed to thrive in analytical method validation, and why are they important?

To thrive in Analytical Method Validation, you need a strong background in analytical chemistry or related sciences, precision in laboratory work, and experience with method development and validation protocols, often supported by a relevant degree. Familiarity with instrumentation such as HPLC, GC, and mass spectrometry, as well as knowledge of regulatory standards like ICH, FDA, or USP, and proficiency in laboratory information management systems (LIMS) are key. Attention to detail, critical thinking, and effective communication are important soft skills for troubleshooting and collaborating with cross-functional teams. These skills ensure robust, compliant analytical methods that underpin product quality and regulatory approval.

What are popular job titles related to Analytical Method Validation jobs in Massachusetts?

For Analytical Method Validation jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Analytical Method Validation jobs in Massachusetts look for?

The top searched job categories for Analytical Method Validation jobs in Massachusetts are:

Analytical Method Validation jobs near you
Infographic showing various Analytical Method Validation job openings in Massachusetts as of August 2026, with employment types broken down into 1% Internship, 91% Full Time, 5% Part Time, and 3% Contract. Highlights an 84% Physical, 6% Hybrid, and 10% Remote job distribution, with an average salary of $118,116 per year, or $56.8 per hour.

Senior Manager, Analytical Development & QC

Relay Therapeutics

Cambridge, MA • On-site

$121K - $172K/yr

Full-time

Posted 23 days ago

Job description

Job Description:

Your Role:

  • You will lead and drive strategy for analytical method development and phase-appropriate method validation/transfer activities supporting full characterization of small molecule NCEs, from early development through late-stage/commercial readiness.
  • Own the analytical strategy for drug substance programs at CDMOs, directing method development, validation, and troubleshooting to enable characterization, release, and stability testing of Relay clinical candidates.
  • Lead the evaluation and introduction of modern analytical technologies, setting direction for how new techniques are incorporated into method development workflows across programs.
  • Provide senior-level review and approval of method transfer/validation protocols, data sets, and reports, ensuring scientific rigor and regulatory readiness.
  • Hold accountability for QC testing oversight across analytical testing labs and DS manufacturing sites, including vendor performance and quality of deliverables.
  • Review and approve method qualification protocols and reports at external laboratories, serving as the final scientific authority on method suitability.
  • Direct the review and QC of raw data from third parties supporting batch release and stability; lead data trending efforts, proactively flag risks to the team, and drive resolution of issues.
  • Manage a portfolio of concurrent projects, prioritizing resources and timelines across programs in a fast-paced, evolving environment.
  • Serve as a cross-functional leader, partnering with CMC, Quality Assurance, and Regulatory Affairs to shape regulatory and development strategy, and representing Analytical Development in cross-functional and external-facing forums.

Your Background:

  • Ph.D. in Analytical Chemistry, Biotechnology, or a related discipline with 8+ years of relevant industry experience (or MS with 10+ years, or BS with 12+ years) in small molecule pharmaceutical analytical development.
  • Demonstrated expertise leading analytical method development, validation, troubleshooting, and quality control programs, including experience directing work performed at external CMOs/CROs.
  • Deep, hands-on analytical knowledge and technical authority in small molecule analytical methods for drug substance and solid-state characterization.
  • Strong working expertise across analytical instrumentation including HPLC, GC, KF titration, XRPD, ICP-MS, UV, and solid-state characterization techniques, with the judgment to guide method selection and troubleshooting strategy.
  • A confident, articulate communicator and cross-functional influencer, capable of representing Analytical Development with contract laboratories, manufacturing partners, and internal leadership.
  • Proven ability to lead through ambiguity and shifting priorities in a fast-paced environment, balancing multiple high-visibility programs against firm timelines.
  • Previous experience filing or working on IND and/or CTA filings is a plus.
  • Strong command of regulatory and analytical guidelines, including cGMPs, ICH, FDA, USP, and other global regulatory requirements, with experience applying this knowledge to shape submission strategy.

Estimated Salary Range: [$121,000 - $172,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location.

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