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Analytical Instrumentation Jobs in California (NOW HIRING)

Astrix Inc

Analytical Chemist

Oakland, CA · On-site

$50 - $60/hr

This position requires an individual with deep hands-on experience in a variety of analytical instrumentation and techniques, and a strong understanding of the regulatory and technical landscapes in ...

Kellton Tech

Instrumentation Technician

Vacaville, CA · On-site

$30 - $51/hr

Analytical Instrumentation Technician Location: Vacaville, CA (Onsite) Pay Range: $30-51/hr. on W2 Schedule: Monday - Friday, 8:00 AM - 5:00 PM (Overtime as required) Position Summary: The Analytical ...

Tentamus California

Analytical Chemist

Irvine, CA · On-site

$65K - $85K/yr

Perform analytical chemistry testing using various instrumentation such as: GCFID, HPLC, ICPMS, GCMSMS * Assist, oversee, and mentor Lab Techs to help them advance in their chemistry career.

Actalent

Sr Analytical Scientist

Hercules, CA

$55 - $64.90/hr

Demonstrated ability to operate, maintain, and troubleshoot LC/MS and HRMS instrumentation. * Strong problem‑solving skills with a track record of resolving complex analytical issues. * Excellent ...

Tentamus California

Analytical Chemist

Irvine, CA · On-site

$65K - $85K/yr

Perform analytical chemistry testing using various instrumentation such as: GCFID, HPLC, ICPMS, GCMSMS * Assist, oversee, and mentor Lab Techs to help them advance in their chemistry career.

Actalent

Analytical Chemist

Hercules, CA

$30 - $35/hr

Hands-on familiarity with analytical instrumentation (HPLC, GC, UV, etc.) * Basic understanding of GMP/GLP environments preferred Strong attention to detail and ability to follow defined procedures ...

Actalent

Analytical Chmist

Hercules, CA · On-site

$30 - $35/hr

Hands-on familiarity with analytical instrumentation such as HPLC, GC, and UV-based systems. * Foundational knowledge of analytical chemistry principles. * Basic understanding of GMP and GLP ...

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Analytical Instrumentation information

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$13

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$35

How much do analytical instrumentation jobs pay per hour?

As of Jun 16, 2026, the average hourly pay for analytical instrumentation in California is $20.13, according to ZipRecruiter salary data. Most workers in this role earn between $16.59 and $20.14 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in analytical instrumentation roles, and how can they be managed?

Professionals in analytical instrumentation often encounter challenges such as troubleshooting complex equipment malfunctions, staying updated with rapidly evolving technologies, and ensuring precise calibration for accurate results. Managing these challenges typically involves ongoing training, collaboration with technical support teams, and following strict maintenance protocols. Engaging in regular professional development and networking with peers can also help stay ahead of industry advancements and best practices.

Is instrumentation in high demand?

Instrumentation professionals, including those in analytical instrumentation, are in high demand across industries such as manufacturing, pharmaceuticals, and environmental testing. Skills in calibration, troubleshooting, and familiarity with tools like chromatography and spectrometry increase employability in this field.

What jobs in the US pay 300,000 a year?

In the field of analytical instrumentation, senior roles such as Lead Instrumentation Engineer, Director of Instrumentation, or specialized consultants can reach or exceed a $300,000 annual salary, especially with extensive experience, advanced certifications, and management responsibilities. These positions often require advanced technical skills, project management, and industry expertise, typically found in large corporations or specialized consulting firms.

What jobs pay $500,000 a year in the US?

In the field of analytical instrumentation, senior roles such as director of instrumentation, chief scientific officer, or specialized consultants in high-demand industries can reach or exceed $500,000 annually, especially with extensive experience, advanced certifications, and leadership responsibilities. These positions often involve managing complex projects, developing new technologies, or overseeing large teams in research, manufacturing, or biotech environments.

What is the difference between Analytical Instrumentation vs Laboratory Technician?

AspectAnalytical InstrumentationLaboratory Technician
Required CredentialsTypically requires a degree in chemistry, chemical engineering, or related fields; certifications in instrumentation are commonUsually requires a high school diploma or associate degree; some certifications may be beneficial
Work EnvironmentSpecialized labs with focus on instrument calibration, maintenance, and data analysisGeneral laboratory settings performing tests, sample preparation, and data recording
Employer & Industry UsageUsed in industries like pharmaceuticals, environmental testing, and manufacturing for precise measurementsCommon in healthcare, research, and quality control labs for routine testing

Analytical Instrumentation specialists focus on operating, maintaining, and calibrating complex analytical instruments, often requiring specialized certifications and advanced degrees. Laboratory Technicians perform routine lab tasks, supporting testing and data collection. While both roles work in laboratory environments, Analytical Instrumentation roles demand more technical expertise with instrumentation systems.

What is analytical instrumentation?

Analytical instrumentation refers to the use of specialized devices and tools to measure, analyze, and quantify chemical, physical, or biological properties of samples. Professionals in this field operate instruments such as spectrometers, chromatographs, and microscopes, often requiring technical skills and knowledge of calibration and data interpretation.

What are the key skills and qualifications needed to thrive in Analytical Instrumentation, and why are they important?

Success in Analytical Instrumentation requires a solid background in chemistry, physics, or engineering, often supported by a relevant degree and experience with laboratory techniques. Familiarity with instrumentation such as HPLC, GC, spectroscopy systems, and software for data analysis is essential, and certifications like ASCP or specific instrument training can be advantageous. Strong analytical thinking, attention to detail, and effective problem-solving skills help professionals excel in troubleshooting and optimizing instrument performance. These competencies are crucial for ensuring accurate data generation, reliable analysis, and maintaining high laboratory standards.
What are popular job titles related to Analytical Instrumentation jobs in California? For Analytical Instrumentation jobs in California, the most frequently searched job titles are:
What job categories do people searching Analytical Instrumentation jobs in California look for? The top searched job categories for Analytical Instrumentation jobs in California are:
Analytical Instrumentation jobs near you
Infographic showing various Analytical Instrumentation job openings in California as of June 2026, with employment types broken down into 99% Full Time, and 1% Part Time. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $41,872 per year, or $20.1 per hour.

Analytical Instrumentation Metrologist -- LC‑MS/HPLC Systems

Danaher Manufacturing

Torrance, CA • On-site

$100K - $115K/yr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 5 days ago

Job description

Shape what’s next in analytical science

Imagine arriving at our Torrance site and stepping into a lab where discovery meets precision. As an on-site member of Phenomenex’s Manufacturing Science & Technology team, you’ll be the go-to expert who keeps our mass spectrometry and chromatography platforms performing flawlessly—so scientists around the world can trust every data point.

Phenomenex, part of Danaher, builds tools that help safeguard human health—ensuring the quality of everyday essentials from food and water to medications. You’ll thrive in a culture of belonging and continuous improvement powered by the Danaher Business System.

A day in the life
  • Start by reviewing maintenance schedules and qualification plans for LC‑MS, GC‑MS, QTOF, triple quad, and HPLC/UPLC instruments.
  • Calibrate, perform preventive maintenance, and complete installation/qualification support to uphold data integrity in GMP/GLP environments.
  • Diagnose mechanical, electrical, software, and analytical performance issues—minimizing downtime through rapid, root-cause troubleshooting.
  • Partner with scientists and engineers as the instrumentation SME, advising on best practices and reliability risks.
  • Document activities in our systems and support continuous improvement initiatives that elevate instrument uptime and compliance.
What you’ll own
  • Installation, calibration, repair, and qualification support for Mass Spectrometry (LC‑MS, GC‑MS, QTOF, triple quad) and HPLC/UPLC systems.
  • Troubleshooting across fluidics, vacuum systems, detectors, and associated software.
  • Subject matter expertise for assigned analytical instrumentation.
Reporting and location

You will report to the Metrology Manager. This is an on-site role based in Torrance within the Manufacturing Science & Technology function.

Qualifications
  • Bachelor’s degree in Engineering, Chemistry, Analytical Sciences, or a related field preferred; equivalent experience considered.
  • 3+ years hands-on servicing of Mass Spectrometry and HPLC systems within regulated pharma/biotech/diagnostics/CRO labs.
  • Strong working knowledge of LC‑MS/MS, HPLC/UPLC principles, fluidics, vacuum systems, detectors, and instrumentation software.
  • Proven experience operating under GMP and/or GLP.

Bonus points for:

  • Automating processes to drive more efficient analyses.
  • Using a CMMS for maintenance planning, documentation, and recordkeeping.
Compensation & benefits

Base salary range: $100,000 – $115,000 (range may be updated). This role is also eligible for bonus/incentive pay.

We offer a comprehensive benefits package (medical/dental/vision, paid time off, 401(k)). Explore our programs at Danaher Benefits Info.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.

You should be proficient in
  • Equipment Troubleshooting
  • Troubleshooting Skills