ZipRecruiter

Log In

1

Analytical Development Jobs in Massachusetts (NOW HIRING)

Alkermes

Supervisor, Analytical Development

Waltham, MA

$131K - $142K/yr

The Analytical Development Supervisor provides technical and operational leadership for small molecule analytical activities within a growing, dynamic Pharmaceutical Development organization. This ...

Alkermes

Supervisor, Analytical Development

Waltham, MA ยท On-site

$131K - $142K/yr

The Analytical Development Supervisor provides technical and operational leadership for small molecule analytical activities within a growing, dynamic Pharmaceutical Development organization. This ...

Biogen

Scientist II, Analytical Development

Cambridge, MA ยท On-site

$117K - $157K/yr

We are seeking a Scientist II to join our Analytical Development team as a Liquid Chromatography (LC) Subject Matter Expert (SME) and Analytical Project Lead. This role is pivotal,leveragingdeep ...

next page

Showing results 1-20

All JobsAnalytical Development JobsAnalytical Development Jobs in Massachusetts

Analytical Development information

See Massachusetts salary details

$41K

$81.9K

$121.8K

How much do analytical development jobs pay per year?

As of Aug 29, 2026, the average yearly pay for analytical development in Massachusetts is $81,894.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,900.00 and $101,600.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in Analytical Development?

To thrive in Analytical Development, you need a solid background in chemistry, biochemistry, or a related field, often supported by a relevant degree and experience in analytical methodologies. Familiarity with laboratory instruments such as HPLC, GC, and mass spectrometry, as well as knowledge of regulatory guidelines like ICH and GMP, is essential. Strong problem-solving skills, attention to detail, and effective communication set standout professionals apart in this role. These skills ensure the accurate development, validation, and transfer of analytical methods critical for product quality and regulatory compliance.

What are some common challenges faced in an Analytical Development role, and how can job seekers prepare for them?

Professionals in Analytical Development often encounter challenges such as developing robust methods for complex samples, meeting tight project deadlines, and ensuring regulatory compliance. To prepare, job seekers should build strong problem-solving skills, gain familiarity with a range of analytical techniques (such as HPLC, GC, and spectroscopy), and stay current with industry regulations like ICH guidelines. Collaborating effectively with cross-functional teams, such as Quality Control and Research & Development, is also essential for success in this role.

What is the difference between Analytical Development vs Quality Control Analyst?

AspectAnalytical DevelopmentQuality Control Analyst
Primary FocusDeveloping and optimizing analytical methods for new productsPerforming routine testing to ensure product quality
Work EnvironmentLaboratories involved in method development and validationQuality control labs conducting batch testing and release
Required CredentialsBachelor's or higher in Chemistry, Biochemistry, or related fields; experience in method developmentBachelor's in Chemistry, Biology, or related fields; experience in testing procedures

Analytical Development professionals focus on creating and refining analytical methods for new products, while Quality Control Analysts perform routine testing to verify product quality. Both roles require similar educational backgrounds and work in laboratory settings, but their responsibilities differ in scope and purpose.

What is analytical development?

Analytical development is a field within pharmaceutical and biotech industries focused on creating and validating methods to analyze the quality, purity, and stability of drug substances and products. It involves developing techniques such as chromatography and spectroscopy, often requiring knowledge of regulatory standards and laboratory skills. Professionals in this area support drug development by ensuring analytical methods are reliable and compliant with industry regulations.

What is the job description of analytical development?

Analytical development involves designing, optimizing, and validating analytical methods to measure the quality and stability of pharmaceutical or chemical products. Professionals in this field use techniques such as chromatography, spectroscopy, and other laboratory tools, often working in regulated environments that require compliance with industry standards and documentation practices.

What are the most commonly searched types of Analytical Development jobs in Massachusetts?

The most popular types of Analytical Development jobs in Massachusetts are:

What are popular job titles related to Analytical Development jobs in Massachusetts?

For Analytical Development jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Analytical Development jobs in Massachusetts look for?

The top searched job categories for Analytical Development jobs in Massachusetts are:

What cities in Massachusetts are hiring for Analytical Development jobs?

Cities in Massachusetts with the most Analytical Development job openings:

Analytical Development jobs near you
Infographic showing various Analytical Development job openings in Massachusetts as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 11% Part Time, and 2% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $81,894 per year, or $39.4 per hour.

Director, Analytical Development

Lexington, MA โ€ข On-site, Remote

Keros Therapeutics
Biotechnology Research and Developmentย โ€ขย 1 - 10 employees
Learn more about Keros Therapeuticsexternal

Full-time

Re-posted 8 days ago

Job description

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-รŸ) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-ฮฒ signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-ฮฒ superfamily and provide disease-modifying benefit to patients.
Job Summary
Keros Therapeutics is seeking an expert in Analytical Science and Protein Characterization to join our team as Director of Analytical Development. The incumbent will lead the analytical strategy, method development, and characterization for our novel protein pipeline. The ideal candidate will have a deep understanding of protein characterization hands-on experience in the laboratory, excellent organizational skills and attention to detail, a demonstrated ability for self-motivated and independent project execution, and a strong desire to learn. This position requires deep expertise in modern analytical chemistry and a strong ability to translate complex data into actionable scientific decisions. The ideal candidate will combine technical depth with proven leadership experience, sound scientific judgment, and the ability to build productive partnerships across internal teams and external collaborators.
Primary Responsibilities
  • Lead analytical development strategy for early to late-stage biologics programs, including Pre-Clinical, Phase I and Phase II/III
  • Develop the strategic implementation of increasing levels of structural, physical, and advanced protein characterization in phase appropriate manner
  • Serve as the subject-matter expert in protein characterization and stability for phase-appropriate development of the pipeline
  • Partner with Manufacturing, Process Development, and Quality teams to define and implement phase-appropriate analytical methods, specifications, and control strategies to support DS and DP
  • Advise and oversee CDMOs' analytical method development, transfer, and validation
  • Collaborate with CDMOs and CROs to develop and optimize a range of analytical assays for the release and characterization on a series of fusion protein and mAb biologics at each stage from preclinical to commercial launch
  • Provide oversight of CDMOs and external testing laboratories, ensuring timelines, data quality, and compliance
  • Ensure analytical methods and specifications are scientifically justified, phase appropriate, and compliant with applicable compendial standards and regulatory guidelines
  • Support comparability, stability, and characterization strategies for process changes and scale-up
  • Provide and develop laboratory based analytical support to upstream and downstream process development to drive new and improved processes for DS production
  • Provide leadership and mentorship to a team of scientists and analysts
  • Support cross-functional team coordinating efforts of the Technical Operations, Quality, and Regulatory to advance programs
  • Drive analytical support for regulatory submissions, including IND amendments, BLA/MAA filings, and responses to health authority questions
  • Author Analytical CMC sections of IND filings, internal SOPs, experimental procedures, training and safety documents

Core Competencies (Required Skills)
  • Experience with biologics analytical support in late-stage activities (Phase 3 and commercialization)
  • Strong background in protein characterization, analytical method development, qualification/validation, and physicochemical characterization of fusion proteins and protein therapeutics
  • Deep understanding of analytical methods and data interpretation to evaluate protein structure, post translational modifications, and characterization
  • Experience supporting transitions from discovery through IND-enabling or early clinical development is strongly valued

Education Requirements and Qualifications
  • MS with 10+ years or PhD with 7+ years in molecular/cellular/structural biology, biochemistry, or a related field
  • Proficiency with biochemical and biophysical methods:
    • CE (CSDS, CIEF and CGE DNA), qPCR, potency, MFI/HIAC, DSF, DLS, DSC, and LCMS/MS peptide mapping & subunit analysis
    • Chromatography: IA, SEC, RP, HIC and IEX
    • Glycosylation: monosaccharide, sialic acid characterization and N-linked Glycan analysis
    • Spectroscopy: UV/Vis, luminescence
  • Experience in biochemistry techniques such as protein expression, gel electrophoresis, protein quantification assays, ELISA, cell-based assays, and enzyme kinetics
  • Understanding of molecular biology, recombinant protein expression and construct design for affinity purification methods; familiarity with standard expression hosts such as mammalian, is a plus
  • Experience in purifying proteins through recombinant processes is a plus
  • Excellent collaboration skills and ability to work cross functionally to achieve objectives
  • Strong work ethic, motivation, and scientific curiosity

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.
Potential base pay range
$200,000-$226,000 USD
Our Diversity, Equity & Inclusion Mission Statement:Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.
Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
Recruitment & Staffing Agencies:Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.

Apply