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Amazon Python Jobs in Indiana (NOW HIRING)

AI Engineer

Indianapolis, IN · On-site

$110 - $140/hr

We're building an internal agent platform on Amazon AgentCore that automates analyst workflows ... Build agent harnesses in Python using LangChain and LangGraph, including tool‑calling, structured ...

New

$100 - $130/hr

We're building an internal agent platform on Amazon AgentCore that automates analyst workflows ... Build agent harnesses in Python using LangChain and LangGraph, including tool‑calling, structured ...

New

Software Engineer, Senior

Carmel, IN · On-site

$122K - $161K/yr

... or Python * Experience developing and consuming RESTful APIs. * Experience working with relational and non-relational databases, like Microsoft SQL, PostgreSQL, Amazon DynamoDB, or MongoDB

Software Engineer, Senior

Carmel, IN

$122K - $161K/yr

... or Python * Experience developing and consuming RESTful APIs. * Experience working with relational and non-relational databases, like Microsoft SQL, PostgreSQL, Amazon DynamoDB, or MongoDB

We're building an internal agent platform on Amazon AgentCore that automates analyst workflows ... Build agent harnesses in Python using LangChain and LangGraph, including tool-calling, structured ...

Manage and support cloud-based data and analytics platforms, including Databricks, Amazon RDS ... Strong production support, troubleshooting, and scripting skills using Python, Bash, or similar ...

AWS Devops Cloud Engineer

Indianapolis, IN · Hybrid

$50.50 - $69/hr

Manage and support cloud-based data and analytics platforms, including Databricks, Amazon RDS ... Strong production support, troubleshooting, and scripting skills using Python, Bash, or similar ...

AWS Devops Cloud Engineer

Indianapolis, IN · On-site

$50.50 - $69/hr

Manage and support cloud-based data and analytics platforms, including Databricks, Amazon RDS ... Strong production support, troubleshooting, and scripting skills using Python, Bash, or similar ...

PCRA - IT Tech Lead/GPP Architect

Indianapolis, IN · On-site

$52.75 - $72.50/hr

... Python, and Spring Boot. • Extensive experience with AWS cloud services including Lambda, ECS/EKS, API Gateway, Amazon S3, DynamoDB, Amazon RDS, and related services. • Experience designing and ...

Mid-Level Full-Stack SaaS Engineer

Indianapolis, IN · On-site

$90 - $150/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Design, develop, test, and maintain full-stack web applications using Python, Django, React, and ... OpenID Connect, SAML, Amazon Cognito, Auth0, Microsoft Entra ID, or similar technologies.

Senior Cloud Engineer with Security Clearance

Crane, IN · On-site

$55.75 - $74.50/hr

Experience with enterprise cloud service providers such as Amazon Web Services (AWS), Google Cloud ... Experience with various scripting languages. (python, bash, powershell, etc.) * Hands-on experience ...

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Showing results 1-20

Amazon Python information

What is an Amazon Python?

An Amazon Python job typically involves using the Python programming language to develop, automate, and optimize software solutions within Amazon's ecosystem. These roles can range from software development and machine learning to data engineering and automation. Employees in these positions work with large-scale data, cloud computing (AWS), and various Python frameworks to enhance efficiency and scalability. Strong problem-solving skills, experience with AWS services, and proficiency in Python are usually required.

What does an Amazon Python do?

As an Amazon Python Developer, your daily responsibilities often include designing, developing, and maintaining backend services or automations using Python, ensuring code quality through testing and reviews, and deploying solutions on AWS infrastructure. You’ll frequently collaborate with product managers, data engineers, and other software developers to deliver new features and resolve issues. Continuous learning and adaptation to new tools and best practices are encouraged, allowing you to contribute to large-scale, high-impact projects. This collaborative and fast-paced environment offers a great opportunity to refine your technical skills and grow within Amazon’s engineering teams.

What are the key skills and qualifications needed to thrive in the Amazon Python position, and why are they important?

To thrive as an Amazon Python Developer, you need advanced proficiency in Python programming, experience with cloud technologies (preferably AWS), and a solid understanding of software development principles. Familiarity with frameworks such as Flask or Django, version control systems like Git, and relevant AWS certifications (e.g., AWS Certified Developer – Associate) are highly valued. Strong problem-solving abilities, attention to detail, and effective communication skills make candidates stand out. These competencies are essential to design scalable applications, collaborate with cross-functional teams, and ensure solutions align with Amazon's technical standards.

Does Amazon use Python?

Amazon employs Python extensively across its services and infrastructure, especially in areas like data analysis, automation, and machine learning. Many Amazon job roles, including those for software engineers, require proficiency in Python and related tools. Python's versatility makes it a valuable skill for Amazon technical positions.

Which Python job is in demand?

Python development roles such as data scientist, backend developer, and automation engineer are currently in high demand across various industries. Skills in frameworks like Django or Flask, along with knowledge of cloud platforms and data analysis, enhance job prospects in these positions.

What are popular job titles related to Amazon Python jobs in Indiana?

For Amazon Python jobs in Indiana, the most frequently searched job titles are:

Infographic showing various Amazon Python job openings in Indiana as of August 2026, with employment types broken down into 1% Internship, 84% Full Time, 9% Part Time, and 6% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution.

AI/ML Engineer Generative AI, Agentic AI & AWS

Apexon

Indianapolis, IN • On-site

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 8 days ago


Job description

Apexon is a digital-first technology services firm specializing in accelerating business transformation and delivering human-centric digital experiences. We have been meeting customers wherever they are in the digital lifecycle and helping them outperform their competition through speed and innovation. Apexon brings together distinct core competencies in AI, analytics, app development, cloud, commerce, CX, data, DevOps, IoT, mobile, quality engineering and UX, and our deep expertise in BFSI, healthcare, and life sciences to help businesses capitalize on the unlimited opportunities digital offers. Our reputation is built on a comprehensive suite of engineering services, a dedication to solving clients toughest technology problems, and a commitment to continuous improvement. Backed by Goldman Sachs Asset Management and Everstone Capital, Apexon now has a global presence of 15 offices (and 10 delivery centers) across four continents.

We enable #HumanFirstDIGITAL

Role Summary

We are looking for a hands-on AI/ML Engineer with strong experience in Python, Generative AI, Agentic AI, Machine Learning, and AWS to build and productionize enterprise AI solutions. The ideal candidate will have experience developing LLM/RAG applications, agentic workflows, ML pipelines, APIs, and cloud-native AI services.

Key Responsibilities

  • Design, develop, test, deploy, and support end-to-end AI/ML solutions using Python and AWS.
  • Build production-grade Python APIs, services, workers, data pipelines, and AI/LLM integrations using FastAPI, Pydantic, boto3, SQLAlchemy, pandas, NumPy, and scikit-learn.
  • Develop RAG pipelines including document ingestion, parsing, chunking, metadata, embeddings, vector/hybrid search, reranking, retrieval, grounding, citations, and access-aware filtering.
  • Build Agentic AI workflows with tools, state, memory, structured outputs, human-in-the-loop approvals, retries, error handling, and observability.
  • Work with LangChain/LangGraph, CrewAI, AWS Strands Agents, or equivalent agent frameworks.
  • Develop GenAI solutions using Amazon Bedrock, foundation models, Knowledge Bases, Agents/AgentCore, and Guardrails.
  • Implement classical ML solutions using scikit-learn, PyTorch/TensorFlow, including training, evaluation, inference, monitoring, and model lifecycle management.
  • Develop AI/ML evaluation frameworks covering golden datasets, prompt testing, retrieval evaluation, LLM evaluation, regression testing, and human review.
  • Implement secure, scalable AWS solutions using SageMaker, Lambda, Step Functions, S3, OpenSearch, API Gateway, ECS/Fargate, EKS, EventBridge, SQS/SNS, RDS/Aurora, DynamoDB, and Glue.
  • Implement IAM, KMS, Secrets Manager, VPC, encryption, CloudWatch, CloudTrail, logging, monitoring, and security controls.
  • Support CI/CD, MLOps, Infrastructure as Code, and automated deployment using Terraform, AWS CDK/CloudFormation, GitHub Actions, CodeBuild/CodePipeline, and ECR.
  • Develop unit, integration, contract, security, performance, and end-to-end tests using pytest.
  • Optimize AI applications for latency, throughput, token consumption, cost, reliability, and scalability.
  • Collaborate with architects, data engineers, QA, DevOps, security, and HCLS teams and mentor other engineers.

Required Skills

Must Have:

  • Python
  • FastAPI / REST APIs
  • Generative AI / LLMs
  • Prompt & Context Engineering
  • RAG
  • Embeddings / Vector & Hybrid Search
  • Agentic AI / AI Agents
  • LangChain / LangGraph / CrewAI / AWS Strands
  • Amazon Bedrock
  • Bedrock Knowledge Bases / Agents / Guardrails
  • Amazon SageMaker
  • AWS Lambda / Step Functions / S3 / OpenSearch / API Gateway
  • SQL
  • Pytest / Automated Testing
  • Docker / Kubernetes
  • Terraform / AWS CDK / CloudFormation
  • CI/CD & MLOps
  • IAM / KMS / Secrets Manager / CloudWatch
  • Machine Learning fundamentals
  • LLM/AI evaluation and observability

Preferred:

  • Healthcare & Life Sciences experience
  • HIPAA / PHI / PII security experience
  • AWS AgentCore
  • PyTorch / TensorFlow
  • PostgreSQL / DynamoDB
  • Event-driven architecture
  • Responsible AI / AI security
  • Human-in-the-loop AI systems

Ideal Candidate

A strong candidate should be hands-on and production-focused, with proven experience taking GenAI/ML solutions from design through coding, testing, AWS deployment, monitoring, and production support.

Our Commitment to Diversity & Inclusion:

Did you know that Apexon has been Certified by Great Place To Work , the global authority on workplace culture, in each of the three regions in which it operates: USA (for the fourth time in 2023), India (seven consecutive certifications as of 2023), and the UK.Apexon is committed to being an equal opportunity employer and promoting diversity in the workplace. We take affirmative action to ensure equal employment opportunity for all qualified individuals. Apexon strictly prohibits discrimination and harassment of any kind and provides equal employment opportunities to employees and applicants without regard to gender, race, color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. You can read about our Job Applicant Privacy policy here Job Applicant Privacy Policy (apexon.com)

Our Commitment to Environment:

Actively contribute to Apexon's commitment to environmental responsibility by following sustainable practices and supporting ESG initiatives.

Our Perks and Benefits:

Our benefits and rewards program has been thoughtfully designed to recognize your skills and contributions, elevate your learning/upskilling experience and provide care and support for you and your loved ones. As an Apexon Associate, you get continuous skill-based development, opportunities for career advancement, and access to comprehensive health and well-being benefits and assistance.

We also offer:

o Health Insurance with Dental & Vision

o 401K Plan

o Life Insurance, STD & LTD

o Paid Vacations & Holidays

o Paid Parental Leave

o FSA Dependent & Limited Purpose care