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Ai Software Jobs in Minnesota (NOW HIRING)

Senior AI/ML Engineer (Hybrid)

Rochester, MN · On-site

$102K - $140K/yr

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer ... You will develop, integrate, and standardize software components and create, maintain, and follow ...

Proficiency with AI software development toolsWork location: Work location: This role follows an on-site working model, requiring the employee to work at least four days a week at the 3M Center in ...

Proficiency with AI software development toolsWork location: Work location: This role follows an on-site working model, requiring the employee to work at least four days a week at the 3M Center in ...

Software/AI Engineer

Virginia, MN · On-site

$100 - $140/hr

Quality Support, Inc. openings for Software/AI Engineers with 10+ years of related experience in submarine electronic subsystem requirements, development and testing. Preferred Virginia Class ...

Senior Software Engineer

Saint Paul, MN · On-site

$123K - $162K/yr

Proficiency with AI software development toolsWork location: Work location: This role follows an on-site working model, requiring the employee to work at least four days a week at the 3M Center in ...

Senior Software Engineer

Saint Paul, MN · On-site

$123K - $162K/yr

Proficiency with AI software development toolsWork location: Work location: This role follows an on-site working model, requiring the employee to work at least four days a week at the 3M Center in ...

Lead Software Engineer, AI Are you passionate about building AI-driven software that transforms how professionals work? Join our fast-moving, forward-thinking group that is creating AI-driven ...

Lead Software Engineer, AI Are you passionate about building AI-driven software that transforms how professionals work? Join our fast-moving, forward-thinking group that is creating AI-driven ...

Showing results 21-40

Ai Software information

See Minnesota salary details

$41.9K

$106K

$161K

How much do ai software jobs pay per year?

As of Sep 4, 2026, the average yearly pay for ai software in Minnesota is $106,040.00, according to ZipRecruiter salary data. Most workers in this role earn between $84,800.00 and $125,200.00 per year, depending on experience, location, and employer.

What is the difference between Ai Software vs Data Scientist?

AspectAi SoftwareData Scientist
Required CredentialsTypically certifications in AI tools, programming languages (Python, R), and machine learningDegree in Data Science, Computer Science, or related fields; often includes certifications in analytics or machine learning
Work EnvironmentDeveloping, testing, and deploying AI models in software development teamsAnalyzing data, building models, and deriving insights in research or business settings
Employer & Industry UsageTech companies, AI startups, software firmsFinance, healthcare, tech, consulting firms

Ai Software involves creating and implementing AI tools and applications, often requiring programming and software development skills. Data Scientists focus on analyzing data, building predictive models, and providing insights. While both roles work with data and machine learning, Ai Software emphasizes software development and deployment, whereas Data Scientists concentrate on data analysis and interpretation.

What is the easiest AI Software job to get?

Entry-level AI software roles such as AI support technician or junior developer are generally the easiest to obtain, often requiring basic programming skills in languages like Python and familiarity with AI frameworks. These positions typically have lower experience requirements and may offer on-the-job training or certifications to help new entrants get started.

What jobs can I get working with AI?

Jobs working with AI include roles such as AI software engineer, machine learning engineer, data scientist, AI researcher, and AI product manager. These positions typically require skills in programming, data analysis, and understanding of AI algorithms, often using tools like Python, TensorFlow, or PyTorch.
Infographic showing various Ai Software job openings in Minnesota as of August 2026, with employment types broken down into 22% Internship, 70% Full Time, 4% Part Time, and 4% Summer. Highlights an 69% In-person, 22% Hybrid, and 9% Remote job distribution, with an average salary of $106,040 per year, or $51 per hour.

Senior AI/ML Engineer (Hybrid)

Mayo Clinic

Rochester, MN • On-site

$102K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 18 days ago


Key responsibilities

  • Develop, integrate, and standardize AI/ML software components for clinical applications.

  • Collaborate with multidisciplinary teams to understand clinical workflows and translate requirements into AI solutions.

  • Design, test, and maintain tools and CI/CD pipelines to facilitate automated AI software development and deployment.


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 705 frontline employees who took The Breakroom Quiz

135th of 898 rated healthcare providers


Job description

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency.
 

As a Senior AI/ML Engineer, you may work on the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines. 
This role is instrumental in providing consultative services to departments and divisions, offering insights into complex business problems. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications.

   Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance             patient care and clinic operations.
   Collaborating with a multidisciplinary team, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs,                   workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI                   solutions.
   Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to lead the design,                   development, and deployment of end-to-end AI solutions for healthcare applications.
   Establishing evaluation methodologies and performance metrics to assess AI solutions' effectiveness, usability, and impact in real-world healthcare settings.
   Explaining data analysis results to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications. 
   Overseeing the engineering of systems crucial for developing and deploying AI solutions.
   Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD             pipelines.
   Contributing to implementing the best practices and standards for AI development and deployment methodologies, tools, and platforms.
   Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. 
   Providing consultative services on areas of expertise to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
   Providing training and education to healthcare staff on AI tools and technologies.
   Contributing to developing new AI methods and technologies that can advance the state-of-the-art in healthcare AI. 

This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

  A master's degree in engineering, computer science, mathematics, health science, or a related field with 4 years of experience, a bachelor's degree with 6 years of             experience. 
  Extensive experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries,                       showcasing an understanding of healthcare technology.
  Demonstrated leadership in managing complex projects, with a proven ability to navigate intricate project requirements and deliver successful outcomes.
  Proficiency in fostering collaboration across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders.
  Demonstrated expertise in cloud infrastructure environment and software development tools.
  Experience working with large, complex, and heterogeneous data sets, preferably in healthcare. 
  Skilled in AI/ML techniques and frameworks.
  Familiarity with best practices in data engineering, data science, AI Engineering, and the MLOps communities.
  Demonstrated initiative in administration, education, software development, and technical reporting. 
  A commitment to mentoring and training less-experienced team members, coupled with strong interpersonal, communication, and time management skills.


Preferred Qualifications: 
  A Ph.D. or other doctorate is preferred. 
  Strong expertise in AI/ML techniques and frameworks, such as deep learning, natural language processing, and Generative AI, with proficiency in tools like Python,           TensorFlow, PyTorch, sci-kit-learn, Keras, etc.
  Knowledge of the healthcare domain, including clinical workflows, electronic health records, medical terminologies, regulatory requirements, and industry standards.
  Familiarity with systems or quality engineering best practices, regulatory standards, and compliance frameworks, with the ability to adapt these effectively to different     project scenarios.
  Demonstrated experience leading technical/quantitative teams in a regulated environment.
  Demonstrated experience creating risk management files and verification/validation strategies for digital health technology products within the healthcare industry.
  Strong expertise in user-centered design, human factors engineering, usability testing methodologies, and evaluation across AI product development. Ability to                 conduct expert reviews using established usability practices and methods. Presents findings in easy-to-understand terms for the business or clinical practice.


What Mayo Clinic employees say

Pay

Benefits

Hours and flexibility

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919