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Remote Python Jobs in Colorado (NOW HIRING)

ML Engineer

Denver, CO · On-site +1

Remote (Preferred U.S. Time Zones) Employment Type: Full-Time Company: Performacentric About ... Build scalable AI applications using Python and FastAPI. * Design and maintain RESTful APIs for AI ...

Senior Data Analyst

Denver, CO · On-site +1

$90K - $120K/yr

100% Remote Full-time Senior Analyst At NuView Analytics - we help companies accelerate the time to ... R or Python experience a plus * Tableau, Power BI, or Looker all stars * Looking for a self-starter ...

100% Remote Full-time Senior Analyst At NuView Analytics - we help companies accelerate the time to ... R or Python experience a plus * Tableau, Power BI, or Looker all stars * Looking for a self-starter ...

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Remote Python information

See Colorado salary details

$13

$61

$90

How much do remote python jobs pay per hour?

As of Jun 20, 2026, the average hourly pay for remote python in Colorado is $61.64, according to ZipRecruiter salary data. Most workers in this role earn between $50.82 and $70.00 per hour, depending on experience, location, and employer.

What are Remote Python jobs?

Remote Python jobs are positions where you work primarily with the Python programming language but do so from a location outside of a traditional office, such as your home or another remote location. These jobs can include roles like software developer, data analyst, backend engineer, or machine learning engineer, all of which use Python for building applications, analyzing data, or automating tasks. Remote Python jobs are popular due to Python's versatility and the growing demand for flexible work arrangements in the tech industry.

What are the key skills and qualifications needed to thrive as a Remote Python Developer, and why are they important?

To thrive as a Remote Python Developer, you need strong programming skills in Python, experience with software development life cycles, and a relevant degree or professional experience. Familiarity with tools like Git, Docker, cloud platforms (e.g., AWS), and frameworks such as Django or Flask is typically required, along with knowledge of remote collaboration tools like Slack and Jira. Excellent problem-solving abilities, self-motivation, and effective communication are crucial soft skills for remote team integration and project delivery. These skills ensure efficient, high-quality code development, seamless teamwork, and the ability to meet project goals independently in a remote environment.

What Are Remote Jobs That Use Python?

Remote jobs that use Python focus on coding software and applications to meet the needs or business objectives of your employer. This may involve working with a database, customizing an existing application, or otherwise modifying software based on its expected environment. You can also find a few remote roles that allow you to teach Python instead of using it. Many remote jobs that use Python also involve coding in other common languages as necessary—Python may be the bulk of the work, but the ability to switch to other modes of programming as needed is essential for success in this field. As a remote employee or independent contractor, you may use virtual office software to coordinate with others, upload software into a central database for testing, or work odd hours to meet the needs of your client.

What is the difference between Remote Python vs Remote Data Analyst?

AspectRemote PythonRemote Data Analyst
Required SkillsPython programming, scripting, libraries (e.g., Pandas, NumPy)Data analysis, SQL, Excel, visualization tools
CertificationsPython certifications, data science coursesData analysis certifications, SQL certifications
Work EnvironmentRemote, tech companies, startupsRemote, finance, marketing, consulting firms
Industry UsageSoftware development, automation, backend servicesBusiness intelligence, market research, reporting

Remote Python roles focus on coding, automation, and software development using Python, while Remote Data Analysts analyze data sets to generate insights. Both roles often work remotely and require analytical skills, but their core responsibilities and tools differ significantly.

How do Remote Python Developers typically collaborate and communicate with their teams?

Remote Python Developers often work closely with distributed teams using collaboration tools like Slack, Zoom, and GitHub. Clear communication and regular check-ins are essential for syncing on project requirements, code reviews, and troubleshooting. Developers are encouraged to document their code thoroughly and proactively update their progress to ensure smooth workflow across different time zones. This environment fosters independence and strong written communication skills, while also providing opportunities to participate in virtual standups, sprint planning, and peer programming sessions.
What are the most commonly searched types of Python jobs in Colorado? The most popular types of Python jobs in Colorado are:
What job categories do people searching Remote Python jobs in Colorado look for? The top searched job categories for Remote Python jobs in Colorado are:
What cities in Colorado are hiring for Remote Python jobs? Cities in Colorado with the most Remote Python job openings:
Infographic showing various Remote Python job openings in Colorado as of June 2026, with employment types broken down into 22% Internship, 67% Full Time, and 11% Contract. Highlights an 100% In-person job distribution, with an average salary of $128,214 per year, or $61.6 per hour.

ML Engineer

Performacentric

Denver, CO • On-site, Remote

Full-time

Posted 11 days ago


Job description

Machine Learning Engineer (Llama AI Platform)

Location: Remote (Preferred U.S. Time Zones)
Employment Type: Full-Time
Company: Performacentric

About Performacentric

Performacentric helps small and mid-market organizations improve profitability, efficiency, visibility, employee performance, customer satisfaction, and supplier performance through custom AI agents, intelligent automation, and connected business systems.

We are building a next-generation AI platform powered by open-source large language models, agentic workflows, and business process automation. We are seeking a Machine Learning Engineer to help design, deploy, and optimize AI solutions built on Llama models and modern Python-based application architectures.

Position Summary

Performacentric is seeking a Machine Learning Engineer with hands-on experience developing and deploying AI applications using Llama 3 8B, Python, and FastAPI. This role will be responsible for building production-grade AI services, optimizing model performance, developing APIs, integrating business systems, and supporting the evolution of Performacentric's AI agent platform.

The ideal candidate combines strong software engineering skills with practical machine learning experience and enjoys working in a fast-paced startup environment where they can directly influence product direction and technical architecture.

ResponsibilitiesAI Model Development & Optimization
  • Deploy, configure, and optimize Llama 3 8B models for production use.
  • Develop prompt engineering, retrieval, and agentic workflows.
  • Fine-tune and evaluate LLM performance for business use cases.
  • Implement Retrieval-Augmented Generation (RAG) architectures.
  • Optimize inference performance, latency, and infrastructure utilization.
  • Monitor model quality and continuously improve response accuracy.
Application Development
  • Build scalable AI applications using Python and FastAPI.
  • Design and maintain RESTful APIs for AI services.
  • Develop backend services supporting AI agents and copilots.
  • Integrate AI solutions with CRM, ERP, communication, and business systems.
  • Implement authentication, authorization, and API security controls.
  • Write clean, maintainable, and well-documented code.
Data & Infrastructure
  • Build and maintain vector database integrations.
  • Develop data ingestion and preprocessing pipelines.
  • Support deployment of AI workloads in cloud and self-hosted environments.
  • Collaborate on model serving, monitoring, logging, and observability.
  • Assist with infrastructure automation and CI/CD processes.
Collaboration
  • Work closely with product, engineering, and leadership teams.
  • Participate in architecture discussions and technical planning.
  • Contribute to AI solution design for client implementations.
  • Mentor junior developers and share best practices.
Required QualificationsTechnical Skills
  • 3+ years of professional software engineering experience.
  • Strong proficiency in Python.
  • Experience building APIs with FastAPI.
  • Experience deploying and working with Llama 3 8B or similar open-source LLMs.
  • Understanding of prompt engineering and LLM optimization techniques.
  • Experience consuming and developing REST APIs.
  • Strong understanding of Git-based development workflows.
  • Familiarity with Linux environments and command-line tools.
  • Experience troubleshooting and optimizing production applications.
Machine Learning Knowledge
  • Understanding of machine learning fundamentals.
  • Experience evaluating AI model performance.
  • Familiarity with embeddings, vector search, and RAG architectures.
  • Knowledge of model inference optimization techniques.
  • Experience working with structured and unstructured datasets.
Preferred Qualifications

Preference will be given to candidates with experience in one or more of the following:

  • Fine-tuning open-source LLMs.
  • ML Engineering and MLOps practices.
  • LangChain, LlamaIndex, Haystack, or similar frameworks.
  • PostgreSQL database administration and optimization.
  • Vector databases such as pgvector, Chroma, Pinecone, Weaviate, or Qdrant.
  • Docker and containerized deployments.
  • Kubernetes orchestration.
  • Azure AI infrastructure and GPU environments.
  • CI/CD pipelines and DevOps automation.
  • Multi-agent AI architectures.
  • Knowledge graph implementations.
  • Business intelligence and analytics platforms.
Success Metrics

Within the first 12 months, the successful candidate will help:

  • Deploy and optimize production AI workloads.
  • Improve AI response quality and accuracy.
  • Reduce inference latency and infrastructure costs.
  • Expand Performacentric's AI agent platform capabilities.
  • Deliver reliable AI integrations for customer environments.
  • Contribute to the development of new AI-powered products and services.
What We Offer
  • Opportunity to work on cutting-edge AI and agentic technologies.
  • Direct influence on product architecture and technical strategy.
  • Remote-first work environment.
  • Competitive compensation based on experience.
  • Professional growth opportunities in one of the fastest-growing areas of software development.
  • Ability to help shape the future of AI-powered business transformation.
How to Apply

Interested candidates should submit:

  • Resume/CV
  • Brief cover letter
  • GitHub profile (if available)
  • Portfolio of AI, machine learning, or software development projects
  • Examples of LLM, FastAPI, or AI agent implementations (preferred)

Join Performacentric and help build the next generation of AI agents that transform how businesses operate, make decisions, and grow.