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Protein Purification Jobs in Raleigh, NC (NOW HIRING)

Managing protein engineering (cloning, expression, and purification) and conducting functional assays to validate structural findings. * Cellular & In Vivo Integration: Utilizing light microscopy for ...

Managing protein engineering (cloning, expression, and purification) and conducting functional assays to validate structural findings. * Cellular & In Vivo Integration: Utilizing light microscopy for ...

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Protein Purification information

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$16

$32

$50

How much do protein purification jobs pay per hour?

As of Jun 14, 2026, the average hourly pay for protein purification in Raleigh, NC is $32.14, according to ZipRecruiter salary data. Most workers in this role earn between $21.01 and $39.71 per hour, depending on experience, location, and employer.

What does a typical day look like for someone working in Protein Purification?

A typical day in Protein Purification involves preparing and setting up purification systems, monitoring processes such as chromatography runs, analyzing sample purity, and maintaining detailed records of results. You’ll often collaborate with research scientists, quality control teams, and other lab staff to meet project deadlines and troubleshoot purification challenges. The work environment is usually a laboratory setting, where safety protocols and attention to detail are paramount. Successful professionals in this field balance hands-on technical tasks with regular communication to ensure the smooth progression of research or manufacturing projects.

What are the key skills and qualifications needed to thrive in the Protein Purification position, and why are they important?

Excelling in Protein Purification requires a solid background in biochemistry or a related life science, with hands-on experience in laboratory techniques such as chromatography, electrophoresis, and buffer preparation. Familiarity with tools like FPLC/HPLC systems, automated fraction collectors, and relevant quality control software is crucial. Attention to detail, problem-solving skills, and strong teamwork abilities distinguish top performers in this role. These skills are essential for ensuring the accuracy, purity, and reproducibility of protein samples in research or industrial environments.

What is a Protein Purification job?

A Protein Purification job involves isolating and refining proteins from biological samples for research, pharmaceutical, or industrial applications. This process includes techniques such as chromatography, centrifugation, and filtration to achieve high purity and functionality. Professionals in this role work in laboratories, biotech firms, or pharmaceutical companies, ensuring quality control and optimizing purification protocols. Strong analytical skills and knowledge of biochemistry are essential for success in this field.

What job categories do people searching Protein Purification jobs in Raleigh, NC look for? The top searched job categories for Protein Purification jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Protein Purification jobs? Cities near Raleigh, NC with the most Protein Purification job openings:
Infographic showing various Protein Purification job openings in Raleigh, NC as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $66,846 per year, or $32.1 per hour.
Postdoctoral Research Associate Dr. Counago Lab

Postdoctoral Research Associate Dr. Counago Lab

UNC-Chapel Hill

Chapel Hill, NC

Full-time

Medical, Vision, PTO

Posted 25 days ago


University Of North Carolina At Chapel Hill rating

7.5

Company rating: 7.5 out of 10

Based on 48 frontline employees who took The Breakroom Quiz

262nd of 537 rated colleges and universities


Job description

Posting Details
Department SOP-SGC Ctr for Chem Biology - 452102 Posting Open Date 06/24/2025 Application Deadline Open Until Filled Yes Position Type Postdoctoral Scholar Position Title Postdoctoral Research Associate Dr. Counago Lab Vacancy ID PDS004580 Full-time/Part-time Full-Time Temporary Hours per week 40 FTE 1 Work Location Chapel Hill, NC Position Location North Carolina, US Hiring Range Dependent on experience and qualifications. Proposed Start Date 08/01/2025 Estimated Duration of Appointment 12 Months
Position Information
Be a Tar Heel!
A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development.
Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country.
UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.
Primary Purpose of Organizational Unit
The UNC Eshelman School of Pharmacy (www.pharmacy.unc.edu) is one of six health science schools (Pharmacy, Nursing, Dentistry, Social Work, Public Health, Medicine) at the University of North Carolina at Chapel Hill and is one of the oldest health science academic programs at Chapel Hill. The School teaches approximately 600 PharmD students and 145 graduate students. The School has built a reputation for its continued pursuit of excellence, rigorous education and training programs, cutting-edge multidisciplinary research, progressive pharmacy practices, efficient business operations, and its outstanding faculty, staff, and students. The School was named the number one School of Pharmacy in the U.S. by the U.S. News and World Report. The School has experienced unprecedented growth and success and continues to strategically position itself for sustained impact, as articulated in the School's Strategic Plan (https://pharmacy.unc.edu/about/oe/strategic-plan/).
Our Vision is to be the global leader in pharmacy and pharmaceutical sciences. Our Mission is to prepare leaders and innovators to solve the world's most pressing health care challenges. We are Advancing Medicine for Life through innovation and collaboration in pharmacy practice, education, research, and public service.
Position Summary
The Structural Genomics Consortium (SGC) at UNC-Chapel Hill is seeking a highly motivated researcher to join our team as part of the NIH-funded Emory-Sage-SGC-Jax TREAT-AD Center. This multi-institutional initiative is focused on accelerating the discovery of new therapeutic targets and strategies for Alzheimer's disease by generating and disseminating high-quality research tools and data.
As a member of the Center's Structural Biology Core, this position will contribute to the development of Target Enabling Packages (TEPs) comprehensive toolkits that include purified proteins, structural data, and biochemical assays to support the broader research community in exploring novel drug targets.
Key Responsibilities:
- Protein Expression and Purification:
Design and execute recombinant protein production workflows in both prokaryotic and eukaryotic expression systems.
- Biochemical and Biophysical Characterization:
Develop and perform assays to identify and characterize protein-ligand interactions, including binding affinity, selectivity, and mechanism-of-action studies.
- Structural Biology:
Determine protein structures using X-ray crystallography and cryo-electron microscopy (cryo-EM) to support target validation and ligand discovery.
- Data Management and Reporting:
Maintain accurate and detailed records of experimental procedures, results, and analyses. Communicate findings regularly with the project team and contribute to collaborative research efforts within the TREAT-AD network.
This role offers a unique opportunity to work at the intersection of chemical biology, neuroscience, and structural biology, contributing to a national effort to uncover new therapeutic avenues for Alzheimer's disease.
Minimum Education and Experience Requirements
PhD in Biological Sciences or Chemicial Biology or related field.
Required Qualifications, Competencies, and Experience
Demonstrated proficiency in molecular biology, including high-throughput cloning and recombinant protein production using both bacterial and eukaryotic expression systems, such as baculovirus-infected insect cells.
Must be skilled in the use of protein purification equipment, including high-speed centrifuges and fast protein liquid chromatography (FPLC) systems.
Expertise in developing and executing biochemical assays is essential, with hands-on experience in techniques such as fluorescence polarization, time-resolved FRET (TR-FRET), FRET, and BRET.
Proficiency in biophysical assay platforms, including isothermal titration calorimetry (ITC) and surface plasmon resonance (SPR), is also required for characterizing protein-ligand interactions.
Contribute to the design, execution, and analysis of DEL-based ligand discovery campaigns, supporting the identification of novel chemical matter for challenging protein targets
Preferred Qualifications, Competencies, and Experience
Experience with DNA-encoded library (DEL) screening is highly desirable.
Special Physical/Mental Requirements Special Instructions
Apply online at https://unc.peopleadmin.com/postings/303083 with a cover letter, CV/resume and a list of at least three (3) professional references with their full contact information.
For information on UNC Postdoctoral Benefits and Services click here
Quick Link https://unc.peopleadmin.com/postings/303083
Posting Contact Information
Department Contact Name and Title Mac Balatico, HR Business Partner Department Contact Telephone or Email mac.t.balatico@unc.edu Postdoctoral Affairs Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the University's Office of Postdoctoral Affairs at (919) 962-9982 or send an email to opahr@unc.edu.
Please note: The Office of Postdoctoral Affairs will not be able to provide specific updates regarding position or application status.
Equal Opportunity Employer Statement
The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.

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About University of North Carolina at Chapel Hill

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The University of North Carolina at Chapel Hill (UNC-Chapel Hill), located in Chapel Hill, NC, US, is renowned for being one of the leading research institutes in the world. Operating within the education industry, this public research university offers a broad range of undergraduate, graduate, and professional programs across various disciplines. UNC-Chapel Hill was chartered in 1789 and has maintained its legacy of academic excellence and innovative research for more than two centuries. The institution operates under the core values of excellence, innovation, engagement, accessibility, diversity, and inclusivity. Their mission is to serve the people of North Carolina and the United States by teaching a diverse community of students to become the next generation of leaders.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Chapel Hill, NC, US

Year founded

1789