POSITION SUMMARY: Dr. Randall Bateman’s lab investigates the causes, and future diagnosis and treatments of Alzheimer’s disease utilizing a wide variety of assays and techniques from basic applications, such as quantitative measurement of stable-isotope labeled peptides to clinical translational studies in diagnostic and therapeutic biomarkers for Alzheimer’s disease. The Bateman Lab is looking for an experienced laboratory manager who can work diligently in a team environment.
This position performs, oversees and coordinates research projects, oversees the entire laboratory to promote smooth operations, regulatory compliance and interaction with other laboratories, and supervises and directs daily activities for lab projects, processes, grants, and contracts. The position requires an individual highly skilled in project planning, administration, and management, and process and procedure development and improvement. This position requires exceptional critical thinking, analytic, writing, and communication skills.
PRIMARY DUTIES AND RESPONSIBILITIES (Essential Functions)
Research project development, implementation, and management: Assist principal investigator with the design of effective and efficient research protocols. Develop and manage project timelines and align across all projects, identify milestones, identify and prioritize project tasks and activities, assign and manage resources, and ensure project timelines are met. Manage project budgets to meet the aims of the study: manage research accounts, allocation of funds, track and approve expenditures, personnel sourcing, confirm receipt of supplies, equipment, and services for payment. Assist with execution of collaboration contracts. Evaluate research results, prepare progress reports to report findings, and discuss project outcomes with other researchers involved. 25 %
Lab processes, operations management, and supervision of lab staff: Evaluate and optimize lab processes and operations including resolution of issues: mass spectrometer usage, lab equipment usage, assay performance and development, supply and resource management. Solve practical problems relating to difficulties with equipment. Personnel management and supervision: Oversee recruitment, selection, hiring, training, evaluating, promoting, disciplinary action, and termination of lab staff and students. Oversee the development and maintenance of lab protocols and Standard Operating Procedures (SOPs). Oversee sample collection, organization, storage, and usage. Manage the Recharge Center for running of mass spectrometry samples including calculation of charged rates, machine usage and time tracking, and invoicing users. 25 %
Grant preparation, pre and post-award management: Oversight of grant preparation and submission including collaborating with other investigators within and external to the university to develop research studies, developing plan and timelines for submission, and identifying and assigning grant preparation tasks. Oversight of grant post-award management to ensure project goals are met. Responsibilities include tracking project progress, budget management, resource management, development and submission of progress reports to funding agencies, assisting with manuscript preparation and submission, and project closeout. 10 %
Financial management and future project planning: Manage overall lab finances and budgets to meet the aims of the all studies: identify opportunities for potential shared costs across projects; track personnel budgets to appropriately manage hiring, promotions, and salary increases; track lab expenditures to forecast future funding needs. 20 %
Data analysis and manuscript preparation: Assist with analysis of research findings including chart, report and figure generation and quality control processing for data analysis. Verify the correctness of the data submitted and makes recommendations based on these analyses. Write manuscripts ensuring inclusion of appropriate co-authors, and proper acknowledgement of related grants. Ensure upload to NIHMS system and a generation of a PMCID number. 10 %
Lab data and sample sharing: Responsible for coordinating the receipt and dissemination of samples or data with other institutions and investigators—including international collaborations Develop, implement, and manage a lab data sharing plan and process including data request review and approval, execution of material transfer and data sharing agreements with requestors, tracking data transfer and follow-up on data analysis, and ensuring communication of data analysis results (publications, presentations, etc.) per study requirements. 10 %
MINIMUM EDUCATION/EXPERIENCE: Master’s degree with 5 years of experience in research lab operations or equivalent combination of education and experience equaling 12 years required.
PREFERRED EDUCATION/EXPERIENCE: PhD or equivalent; background or experience in the following areas: biological science, analytical chemistry. Experience with immunoprecipitation and mass spectrometer analysis.
CRITICAL SKILLS AND EXPERTISE:
· Experience in managing aims and goals of large, complex efforts, organizing and executing a variety of projects; should be a results- driven, team leader
· Highly skilled in project planning, administration and management with expertise in Gantt charts, resource management
· Experience with process and procedure development and optimization; proven ability to evaluate, troubleshoot and improve a variety of processes
· Excellent analytical, reasoning and problem solving skills, a critical thinker. Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner.
· Knowledge and application of the scientific method
· Excellent scientific writing and oral communication skills; able to work independently and as part of a team.
Experience in research design, analysis, and execution including protocol development, especially in aging and dementia
· Excellent communication and interpersonal skills; must have the ability to effectively communicate with all levels of personnel
Expert organizational skills; detail-oriented
· Computer literacy including the ability to use a variety of software packages to analyze data and familiarity with citation management software
· Experience with database management of a large data set, analysis and generation of charts and reports
DECISION MAKING AND IMPACT: Position will be responsible for making key scientific and project planning decisions and recommendations.
FINANCIAL/OPERATIONAL IMPACT: Position will be responsible for making key financial and operational decisions and recommendations.
Internal – Contact with multiple departments within the university
External – Contact with external researchers, pharmaceutical partners, and vendors
Given – Supervision of lab staff
Received – Guidance and direction provided by Dr. Randall J. Bateman
JOB LOCATION - Bateman Lab, located on the Washington University Medical School Campus in St. Louis Missouri.
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
The DIAN-TU’s primary goal is to implement effective, safe and efficient clinical trials that have the highest likelihood of success in advancing overall treatments as well as scientific understanding of inherited Alzheimer’s disease. In addition, research within the DIAN-TU is likely to advance broader understanding of all types Alzheimer’s disease with regards to causes, early detection/diagnosis, the effects of multiple classes of drugs and the impact of treating Alzheimer’s disease early.
Washington University School of Medicine
Why Work Here?The Dominantly Inherited Alzheimer Network is an international research partnership involving institutions in the United States, Australia, Europe, Asia and South America focused on dominantly inherited Alzheimer’s disease. The clinical trials are designed and coordinated by the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), based at Washington University School of Medicine in St. Louis The DIAN-TU’s primary goal is to implement effective, safe and efficient clinical trials that have the highest likelihood of success in advancing overall treatments as well as scientific understanding of inherited Alzheimer’s disease. In addition, research within the DIAN-TU is likely to advance broader understanding of all types Alzheimer’s disease with regards to causes, early detection/diagnosis, the effects of multiple classes of drugs and the impact of treating Alzheimer’s disease early.
Washington University School of Medicine is consistently ranked among the best places to work in St. Louis.
Saint Louis, MO