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Associate Director / Director, Clinical Sciences

Turning Point Therapeutics, Inc.
San Diego, CA
  • Expired: April 13, 2022. Applications are no longer accepted.

About Turning Point Therapeutics: Turning Point is a growing clinical-stage precision oncology company with a pipeline of internally discovered investigational drugs designed to address key limitations of existing cancer therapies. The company is driven to develop therapies that mark a turning point for patients in their cancer treatment. We are applying novel small molecule design approaches integrating tumor biology and structure-based drug design to develop a new generation of proprietary targeted agents that we believe will have the potential to address important unmet medical needs for patients. Our vision, mission, and culture underpin everything we do.

Turning Point's vision is to be the leader in precision oncology. Our mission is to bring differentiated therapies to patients with cancer as rapidly as possible. Turning Point's culture unifies our team and is rooted in four core values: * Human Centric.

Our work revolves around the patients we aim to serve, as well as the team members we innovate alongside. We relentlessly pursue new therapies, all with the intent to improve the lives of people with cancer. * Speed Where it Matters. We make decisions thoughtfully and quickly without sacrificing quality or integrity.

Our team works with a sense of urgency to achieve its goals. We are dynamic with a purpose. * Extreme Team. We build strong relationships based on transparency and open communication.

Determined but humble, we combine hard work and fun to achieve the extraordinary. * Resilience. Adaptive and nimble, we boldly embrace and drive change to continually evolve. We are continuous learners, recognizing challenges as opportunities to creatively solve problems. The opportunity: We are seeking a highly motivated Associate Director/Director, Clinical Sciences who will report to the Executive Director, Clinical Sciences, and work closely with study physicians and study teams to support corporate strategy and clinical development deliverables for one or more assets.

This position must support the program's medical monitor/director in the design, conduct, and assessment of the clinical studies including assessment of efficacy and safety signals, as required. What you will do: * Work closely with the clinical sites, CROs, and internal clinical team (medical monitor; clinical operations team; data manager; and statistician) on the delivery of clinical data; interpretation of the data and overall data cleaning with the internal team. * Develop and maintain strong working relationships with investigators and KOL's and conduct thorough analyses of current standard of care in focused therapeutic areas to support advisory boards and development plans. * Work closely with the medical writers in the evaluation of the clinical data and drafting of clinical protocols, investigator brochures, and regulatory documents. * Conduct literature searches, draft regulated clinical documents, publication abstracts, presentations, and publications. * Support the execution of clinical trials on time by working in a multi-disciplinary team setting with members from within company, CROs and consultants. * Support corporate strategy and clinical development department deliverables for clinical trials and programs by helping with design of scientifically sound clinical protocols and ensuring decision quality clinical data is being generated on an ongoing and timely basis. * Serve as the key point person with the clinical sites, CRO and medical monitor on the execution of the clinical trials; data delivery; data cleaning activities; and data interpretation. * Partner with data management and study medical monitor/ director for CRF design, instructions, data review plan and conduct frequent clinical data listing review. * Partner with biostatistics and study medical monitor/director for statistical analysis plan review and finalization. * In conjunction with study medical monitor, create and/or review slides for internal and external meetings such as investigator meetings, SIVs, and company-wide meetings. * Participate in long-term clinical development and planning a pathway to regulatory registration for assigned therapeutic area(s). * Serve as clinical science representative on cross-function teams as assigned. * Author or contribute to production of high-quality documents or sections thereof that are scientifically sound including clinical protocols and amendments, clinical study reports, investigator brochures, documents to support health authority interactions including DSURs, publications that include abstracts as well as congress presentations. * Support development of target/pathway engagement assays for selecting therapeutically relevant doses and schedules; support development of stratification biomarkers. We'd love to hear from you if: * You have an advanced science degree such as PhD, PharmD, MS or equivalent * You have 5 or more years of clinical trial experience in clinical development within pharmaceutical industry * You have prior experience in oncology/hematology clinical development * You have excellent communication and presentation skills and ability to work effectively across multiple multidisciplinary teams * You can multi-task, prioritize and work independently * You can influence others in a fast-growing clinical development organization * You can develop successful collaborations with academic and other external partners * You exercise good judgment and have demonstrated sound decision-making skills in making critical go/no-go decisions Benefits with you in mind: Turning Point cares about each team member and their wellbeing. We take great pride in cultivating an outstanding employee experience where team members thrive and do their best work. For full-time employees, we offer competitive salaries, bonuses, and equity incentives.

Full-time employees also enjoy competitive benefit options, including medical, dental, vision, disability, and life insurance. We also offer full-time team members an HSA with a generous employer contribution, as well as healthcare and dependent care FSAs. Turning Point supports employee retirement goals with a group 401K plan that includes an excellent company match.

We know that time with family and personal time to recharge is important, and that's why we offer full-time employees paid company holidays, a winter holiday season shutdown, vacation, and sick time. Full-time employees also have generous leave programs, employee referral bonuses and onsite perks such as a subsidized lunch delivery service, gym access, and a stocked kitchen made available during office hours. We're better together: At Turning Point, we are committed to maintaining a diverse and inclusive working environment. When we say 'diverse,' we mean it in all senses of the word: not only in race, gender, ethnicity, age and orientation, but also in our interests, drivers and passion points.

We believe our individual differences and perspectives are what make us stronger as a team and unite us in our purpose. Our hybrid work environment provides flexibility for individuals and empowers teams to collaborate and build relationships in meaningful ways. We safeguard equal rights and respect for all individuals, regardless of race, color, religion, sex, national origin, age, disability, creed, genetic information, sexual orientation, gender identity or expression, ancestry, veteran status, or other applicable, legally protected characteristics.

Turning Point Therapeutics, Inc.

Address

San Diego, CA
92140 USA

Industry

Healthcare

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